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| 1 | Trends in incidence and management of cancer of the ampulla of Vater显示文摘AIM:To provide trends in incidence,management and survival of cancer of the ampulla of Vater in a welldefined French population.METHODS:Data were obtained from the populationbased digestive cancer registry of Burgundy over a34-year period.Age-standardized incidence rates were computed using the world standard population.Average annual variations in incidence rates were estimated using a poisson regression.A univariate and multivariate relative survival analysis was performed.RESULTS:Age-standardized incidence rates were0.46 and 0.30 per 100000 inhabitants for men and women,respectively.Incidence rate increased from0.26(1976-1984)to 0.58(2003-2009)for men and remained stable for women.Resection for cure was performed in 48.3%of cases.This proportion was stable over the study period.Among cases with curative resection,pancreatico-duodenectomy was performed in94.0%of cases and ampullectomy in 6.0%of cases.A total of 50.8%of cancers of the ampulla of Vater were diagnosed at an advanced stage.Their proportion remained stable throughout the study period.The overall1-and 5-year relative survival rates were 60.2%and27.7%,respectively.Relative survival did not vary over time.Treatment and stage at diagnosis were the most important determinants of survival.The 5-year relative survival rate was 41.5%after resection for cure,9.5%after palliative surgery and 6.7%after symptomatic treatment.In multivariate analysis,only stage at diagnosis significantly influenced the risk of death.CONCLUSION:Cancer of the ampulla of Vater is still uncommon,but its incidence increased for men in Burgundy.Diagnosis is often made at an advanced stage,dramatically worsening the prognosis. | Florian Rostain Samia Hamza Antoine Drouillard Jean Faivre Anne-Marie Bouvier C?me Lepage | 2014 | World Journal of Gastroenterology2014，20，29： | 5 |
| 2 | Epidemiology and Management of Liver Metastases From Colorectal Cancer显示文摘 | Sylvain Manfredi C?me Lepage Cyril Hatem Olivier Coatmeur Jean Faivre Anne-Marie Bouvier | 2006 | Annals of Surgery2006，，2： | 2 |
| 3 | Feasibility of breast preservation in the treatment Of occult primary carcinoma presenting with axillary metastases显示文摘 | Vlastors G Jean ME Mirza AN | 2001 | Ann Surg Ontol2001，8，： | 1 |
| 4 | Feasibility of breast preservation in the treatment of occult primary carcinoma presenting with axillary metastases 显示文摘 | Vlastos G Jean ME Mirza AN | 2003 | Ann Surg Oncol2003，8，5： | 1 |
| 5 | Feasibility of breast preservation in the treatment of occult primary carcinoma presenting with axillary metastasis显示文摘 | Vlastos G Jean ME Mirza AN | 2001 | Ann Surg Oncol2001，8，5： | 1 |
| 6 | Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia显示文摘 | Catherine M. Pastor Jér?me Pugin Brenda Kwak Marc Chanson Fran?ois Mach Antoine Hadengue Jean Louis Frossard | 2004 | Critical Care Medicine2004，，8： | 1 |
| 7 | CML9, an Arabidopsis calmodulin‐like protein, contributes to plant innate immunity through a flagellin‐dependent signalling pathway显示文摘 | Louis‐Jér?me Leba Cécilia Cheval Inmaculada Ortiz‐Martín Benoit Ranty Carmen R. Beuzón Jean‐Philippe Galaud Didier Aldon | 2012 | The Plant Journal2012，，6： | 1 |
| 8 | Feasibility of breast preservation in the treatment of occult primary carcinoma presenting with axillary metastases显示文摘 | Vlastos G Jean ME Mirza AN | 2001 | Ann Surg Oncol2001，8，5： | 1 |
| 9 | Feasibility of breast preservation in the treatment of occult primary carcinoma a presenting with axillary metastases显示文摘 | Vlastos G Jean ME Mirza A N | 2001 | Ann Surg Oncol2001，8，5： | 1 |
| 10 | Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia显示文摘 | Catherine M. Pastor Jér?me Pugin Brenda Kwak Marc Chanson Fran?ois Mach Antoine Hadengue Jean Louis Frossard | 2004 | Critical Care Medicine2004，，8： | 1 |
| 11 | Spinal Cord Monitoring in Scoliosis Surgery Using an Epidural Electrode. Results of a Prospective, Consecutive Series of 191 Cases显示文摘 | Franck Accadbled Patrice Henry Jér?me Sales de Gauzy Jean Philippe Cahuzac | 2006 | Spine2006，，22： | 1 |
| 12 | Feasibility of breast preservation in the treatment of occult primary carcinoma presenting with axillary metastases 显示文摘 | Vlastos G Jean ME Mirza AN | 2001 | Ann Surg Oncol2001，8，5： | 1 |
| 13 | A simple test to estimate the salinity resistance of fish with specific application to O. niloticus and S. melanotheron显示文摘 | Gilles Lemarié Jean Fran?ois Baroiller Frédéric Clota Jér?me Lazard Antoine Dosdat | 2004 | Aquaculture2004，，1： | 1 |
| 14 | Inflammatory fibrosarcoma of mesentery and retroperitoneum显示文摘 | Franz ME | 1991 | Am J Suryg P athol1991，15，： | 1 |
| 15 | Feasiblity of breast preaservation in the treatment of occult primary carcinoma presenting with axillary metastases显示文摘 | Vlastos G Jean ME Mirza AN | 2001 | Ann Surg Oncol2001，8，5： | 1 |
| 16 | Feasibility of breast preservation in the treatment of occult primary carcinoma presenting with axillary metastases 显示文摘 | Vlastos G Jean ME Mirza AN | 2001 | Ann Surg Oncol2001，8，5： | 1 |
| 17 | Salicylate induces tinnitus through activation of cochlear NMDA receptors显示文摘 | Guitton M J Jean C Jer? Me R | 2003 | Journal of Neuroscience2003，23，9： | 1 |
| 18 | A general transcrip- tion factor forms a stable complex with RNA polymerase B (11) 显示文摘 | Zheng XM Vincent M Jean ME | | Cell0，50，3： | 1 |
| 19 | Determination of the chemical mechanism of chromate conversion coating on magnesium alloys EV31A显示文摘 | Sébastien Pommiers Jér?me Frayret Arnaud Uhart Jean Bernard Ledeuil Jean-Charles Dupin Alain Castetbon Martine Potin-Gautier | 2014 | Applied Surface Science2014，，： | 1 |
| 20 | Efficient non-gated remote filament-induced breakdown spectroscopy of metallic sample 显示文摘 | LIU W XU H L ME JEAN G | 2007 | Spectrochim Acta Part B2007，62，1： | 1 |
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