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| 1 | Screening and molecular characterization of Serratia marcescens VITSD2: A strain producing optimum serratiopeptidase显示文摘当前的工作被尝试孤立并且描绘生产 Serratia sp 的 serratiopeptidase。在之中 10 细菌孤立 7 个种类作为 Serratia sp 被识别。从 7 个种类,一个人显示出有势力解朊的活动并且为进一步的研究选择了。基于词法、生物化学、分子的描述,有势力孤立(RH03 ) 作为 Serratia marcescens 被识别(GenBank 就职数字:KC961637 ) 并且种类被指定为 Serratia marcescens VITSD2。serratiopeptidase 的生产在 trypticase 大豆肉汤被执行,酶部分用铵硫酸盐降水和分离被净化。特定的活动被酷蛋白水解作用试金决定并且被发现是为粗略的、猛抛并且渗析的样品的 12.00, 21.33,和 25.40 units/mg。朊酶的分子的重量被 SDS 页决定,是 50 kDa 被发现。生产 serratiopeptidase 的抗菌剂活动对 Pseudomonas aeruginosa MTCC 号码 4676 显示出中等活动(12 公里) 并且 Escherichia coli MTCC 号码 1588 (15 公里) 。 | C. Subathra DEVI Renuka ELIZABETH JOSEPH Harini SARAVANAN S. Jemimah NAINE V. Mohana SRINIVANSAN | 2013 | Frontiers in Biology2013，8，6： | 4 |
| 2 | Delayed diagnosis of alpha-1-antitrypsin deficiency following post-hepatectomy liver failure: A case report显示文摘Post-hepatectomy liver failure(PHLF) is a leading cause of morbidity and mortality following major liver resection. The development of PHLF is dependent on the volume of the remaining liver tissue and hepatocyte function. Without effective pre-operative assessment, patients with undiagnosed liver disease could be at increased risk of PHLF. We report a case of a 60-year-old male patient with PHLF secondary to undiagnosed alpha-1-antitrypsin deficiency(AATD) following major liver resection. He initially presented with acute large bowel obstruction secondary to a colorectal adenocarcinoma, which had metastasized to the liver. There was no significant past medical history apart from mild chronic obstructive pulmonary disease. After colonic surgery and liver directed neo-adjuvant chemotherapy, he underwent a laparoscopic partially extended right hepatectomy and radio-frequency ablation. Post-operatively he developed PHLF. The cause of PHLF remained unknown, prompting reanalysis of the histology, which showed evidence of AATD. He subsequently developed progressive liver dysfunction, portal hypertension, and eventually an extensive parastomal bleed, which led to his death; this was ultimately due to a combination of AATD and chemotherapy. This case highlights that formal testing for AATD in all patients with a known history of chronic obstructive pulmonary disease, heavy smoking, or strong family history could help prevent the development of PHLF in patients undergoing major liver resection. | Benjamin Norton Jemimah Denson Christopher Briggs Matthew Bowles David Stell Somaiah Aroori | 2016 | World Journal of Gastroenterology2016，22，11： | 3 |
| 3 | Low hematocrit and serum albumin concentrations underlie the overestimation of tacrolimus concentrations by microparticle enzyme immunoassay versus liquid chromatography-tandem mass spectrometry显示文摘 | Nigel W Christopher EG Jemimah EA | 2005 | Clin Chem2005，51，3： | 1 |
| 4 | In vitro antimicrobial evaluation and phytoconstituents of Moringa oleifera pod husks显示文摘 | Daljit Singh Arora Jemimah Gesare Onsare | 2014 | Industrial Crops & Products2014，，： | 1 |
| 5 | Exploring the bioactive potential of Serriatia marcescens VITAPI (Acc: 1933637) isolated from soil显示文摘背景 Serratia 是有效地生产解朊的酶的细菌的最重要的组之一并且知道拥有反煽动性的性质。当前的学习的主要焦点是从 Serratia mascescens 提取酶 serratiopeptidase 和颜料 prodigiosin。Prodigiosin 是细菌 Serratia marcescens 生产的红有颜色的颜料。因为它的大应用,它作为一个珍贵分子正在出现。Serratia marcescens 的 pigmented 紧张不比颜料得非的紧张剧毒,这已经被证明了。而且我们获得了的紧张从显示那 prodigiosin 的农场土壤,生产能用这紧张安全地被带。在礼品的方法学习, isolate VITASP 紧张被词法、生物化学、分子的研究证实。酶和颜料为抗氧化剂被分析,反煽动性、细胞毒素的性质。结果 isolate 进一步与 99% 类似作为 Serratia 被证实并且鉴别 marcescens。有 86% 的显示出的有势力基清除效果和酶被发现禁止 83% 的提取颜料,它与维生素酸标准相比重要。在里面处于控制试验性的条件的颜料的反煽动性的效果揭示了的 vitro 它在 88% 点的保护和有 90% 的酶。阿司匹林被用作参考药。现在的调查结果展出了集中依赖者抑制。颜料的细胞毒素的生物鉴定显示出是的 IC 50 值(50 ) 有与积极控制相比统计上重要的 63% cytotoxicity 的 g/mL。结论因此,它看起来是补救的必需品和申请研究。它可以结果对在解决与人的健康联系的许多问题的人类高度有益。 | Aruna Muthukumar Pallavi Pradeep Isha Thigale Mohanasrinivasan V. Jemimah Naine S. C. Subathra Devi | 2016 | Frontiers in Biology2016，11，6： | 1 |
| 6 | The study of marine corrosion of copper alloys in chlorinated condenser cooling circuits: The role of microbiological components显示文摘 | Carvalho Maria L Jemimah Doma Magdalena Sztyler | 2014 | Bioelectrochemist2014，97，： | 1 |
| 7 | Bioactive compounds from marine Streptomyces sp. VITPSA as therapeutics显示文摘背景海洋的放射菌类是显示出不同生物活动的新第二等的代谢物的有效制片人,包括抗菌剂,抗真菌, anticancer,杀虫,并且酶抑制活动。方法种类 Streptomyces sp 的词法、生理、生物化学的性质。VITPSA 被常规方法证实。抗菌剂,抗氧化剂, Streptomyces sp 的反煽动性、反糖尿病、细胞毒素的活动。VITPSA 摘录是坚定的。媒介为第二等的代谢物的生产被优化。第二等的代谢物的描述和鉴定被高效的液体层析,煤气的层析团光谱学,和 Fourier 变换进行红外线的光谱学分析。种类显示出的结果重要抗菌剂,抗氧化剂,和细胞毒素的活动,中等反煽动性的活动,和没有令人满意的反糖尿病的活动。Streptomyces sp 的乙醇醋酸盐摘录。VITPSA 在 0.5 mg/mL 对二个克积极、克否定的细菌显示出最大的抗菌剂活动。粗略的摘录的抗氧化剂潜力与 95.1% 抑制在 0.5 mg/mL 展出了强壮的减少的力量活动。细胞毒素的效果被发现是 MCF-7 房间线上的 50 g/mL 的 IC 50 。由一个因素分析的优化的试验性的设计揭示了最有利的蔗糖,酵母摘录, pH (7.25 ) ,和温度(28 饴吗?? | S. Pooja T. Aditi S. Jemimah Naine C. Subathra Devi | 2017 | Frontiers in Biology2017，12，4： | 0 |
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