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| 1 | Regulation of macrophage activation in the liver after acute injury: Role of the fibrinolytic system显示文摘The liver functions,in part,to prevent exposure of the body to potentially harmful substances ingested in the diet.While it is highly efficient at accomplishing this,it is frequently prone to liver injury due to the biotransformation of xenobiotics into toxic metabolites.To counter this injury,the liver has evolved a unique capacity to rapidly and efficiently repair itself.Successful resolution of acute liver injury relies on hepatic macrophage populations that orchestrate the reparative response.After injury,Kupffer cells,the resident macrophages of the liver,become activated and secrete proinflammatory cytokines.These cytokines recruit other immune cells,including monocyte-derived macrophages,to the liver where they contribute to the repair process.Monocyte-derived macrophages traffic into the necrotic foci where they rapidly phagocytose dead cell debris.Simultaneous with this process,these cells change phenotype from a proinflammatory macrophage to a prorestorative macrophage that produce pro-mitogenic growth factors and antiinflammatory cytokines.Ultimately this process triggers resolution of inflammation,and along with proliferation of other hepatic cells,restores the liver architecture and function.While the mechanisms regulating specific macrophage functions during repair remain to be elucidated,recent studies indicate a key role for the fibrinolytic system in coordinating macrophage function during repair.In this review,we will highlight the function and role of hepatic macrophages in repair after acute liver injury,and will discuss the role of the fibrinolytic enzyme,plasmin,in regulation of these various processes. | Katherine Roth Jenna Strickland Bryan L Copple | 2020 | World Journal of Gastroenterology2020，26，16： | 3 |
| 2 | Microstructure and Mechanical Properties of Dispersion Strengthened by Atomized Melt Deposition Process显示文摘 | Hariprasad S Sastru S L Jenna K L | 1993 | Metal Trans1993，24，4： | 1 |
| 3 | Production of electricity from proteins using a microbial fuel cell 显示文摘 | Jenna H M Bruce E L | 2006 | Water Environ Res2006，78，5： | 1 |
| 4 | Weight bearing orders after hip fracture surgery: A quality assurance project显示文摘 | Joyce A Mammel MN Jenna L | 2008 | Journal of Ortho- paedic Nursing2008，，12： | 1 |
| 5 | Photochemical coenzyme regeneration in an enzymatically active optical material显示文摘 | Jenna L Rickus Pauline L Chang Allan J Tobin | 2004 | J Phys Chem B2004，108，26： | 1 |
| 6 | Thin-film silica sol-gel coatings for neural microelectrodes 显示文摘 | Andrew L P Salah S Jenna L R | 2009 | J Neurosci Meth2009，180，： | 1 |
| 7 | Provenance establishment of coffee using solution ICP-MS and ICP-AES显示文摘 | JENNA L VALENTIN R JOHN W | 2013 | Food Chemistry2013，141，： | 1 |
| 8 | Loss of Gatal but Not Gata2 Converts Erythropoiesis to Myelopoiesis in Zebrafish Embryos显示文摘 | Jenna L Galloway Rebecca A Wingert | 2005 | Developmental Cell2005，8，1： | 1 |
| 9 | Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function显示文摘 | Wendy A N Jenna L A Danielle M R | 2010 | Respir Res2010，11，1： | 1 |
| 10 | Manual versus automated γ-H2AX foci analysis across five European laboratories: Can this assay be used for rapid biodosimetry in a large scale radiation accident?显示文摘 | Kai Rothkamm Stephen Barnard Elizabeth A. Ainsbury Jenna Al-hafidh Joan-Francesc Barquinero Carita Lindholm Jayne Moquet Marjo Per?l? Sandrine Roch-Lefèvre Harry Scherthan Hubert Thierens Anne Vral Veerle Vandersickel | 2013 | Mutation Research - Genetic Toxicology and Environmental Mutagenesis2013，，： | 1 |
| 11 | En- hanced bioproduction of carvone in a two-liquid-phase partitioning bioreactor with a highly hydrophobic bio- catalyst 显示文摘 | Jenna L E M Emily T B Helen C D | 2008 | Biotechnol Bioeng2008，101，4： | 1 |
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