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| 1 | Tamoxifen:an FDA approved drug with neuroprotective effects for spinal cord injury recovery显示文摘Spinal cord injury(SCI) is a condition without a cure,affecting sensory and/or motor functions.The physical trauma to the spinal cord initiates a cascade of molecular and cellular events that generates a non-permissive environment for cell survival and axonal regeneration.Among these complex set of events are damage of the blood-brain barrier,edema formation,inflammation,oxidative stress,demyelination,reactive gliosis and apoptosis.The multiple events activated after SCI require a multi-active drug that could target most of these events and produce a permissive environment for cell survival,regeneration,vascular reorganization and synaptic formation.Tamoxifen,a selective estrogen receptor modulator,is an FDA approved drug with several neuroprotective properties that should be considered for the treatment of this devastating condition.Various investigators using different animal models and injury parameters have demonstrated the beneficial effects of this drug to improve functional locomotor recovery after SCI.Results suggest that the mechanism of action of Tamoxifen administration is to modulate anti-oxidant,anti-inflammatory and anti-gliotic responses.A gap of knowledge exists regarding the sex differences in response to Tamoxifen and the therapeutic window available to administer this treatment.In addition,the effects of Tamoxifen in axonal outgrowth or synapse formation needs to be investigated.This review will address some of the mechanisms activated by Tamoxifen after SCI and the results recently published by investigators in the field. | Jennifer M.Colón Jorge D.Miranda | 2016 | Neural Regeneration Research2016，11，8： | 7 |
| 2 | High-performance oxygen reduction and evolution carbon catalysis: From mechanistic studies to device integration显示文摘能容易集成于存在的高效、便宜的氧减小和进化催化剂的发展设备为利用 O 2-H2 O 化学,例如再生燃料房间和金属空气电池。此处,我们报导 NH 3-activated 做 N 的层次碳(NHC ) 催化剂经由一条可伸缩的线路综合了,并且表明它的设备集成。NHC 催化剂为氧减小反应(ORR ) 和氧进化反应(OER ) 展出了好性能,当综合时,借助于电气化学的研究和评估示威了进一个再生燃料房间的氧电极。为 ORR 和 OER 观察的活动比得上最先进的磅和红外催化剂在碱的环境完成的那些。我们进一步通过密度为电气化学的活动作为活跃地点识别了碳缺点的关键角色功能的理论计算和高分辨率的 TEM 可视化。这个工作加亮 NHC 的潜力在再生燃料房间并且可能代替商业宝贵金属为断断续续的可更新的精力的划算的存储的金属空气电池。 | John W. F. To Jia Wei Desmond Ng Samira Siahrostami Ai Leen Koh Yangjin Lee Zhihua Chen Kara D. Fong Shucheng Chen Jiajun He Won-Gyu Bae Jennifer Wilcox Hu Young Jeong Kwanpyo Kim Felix Studt Jens K. Nфrskov Thomas F. Jaramillo Zhenan Bao | 2017 | Nano Research2017，10，4： | 4 |
| 3 | Using strategically applied grazing to manage invasive alien plants in novel grasslands显示文摘Introduction:Novel ecosystems that contain new combinations of invasive alien plants(IAPs)present a challenge for managers.Yet,control strategies that focus on the removal of the invasive species and/or restoring historical disturbance regimes often do not provide the best outcome for long-term control of IAPs and the promotion of more desirable plant species.Methods:This study seeks to identify the primary drivers of grassland invasion to then inform management practices toward the restoration of native ecosystems.By revisiting both published and unpublished data from experiments and case studies within mainly an Australian context for native grassland management,we show how alternative states models can help to design control strategies to manage undesirable IAPs by manipulating grazing pressure.Results:Ungulate grazing is generally considered antithetical to invasive species management because in many countries where livestock production is a relatively new disturbance to grasslands(such as in Australia and New Zealand as well as Canada and the USA),selective grazing pressure may have facilitated opportunities for IAPs to establish.We find that grazing stock can be used to manipulate species composition in favour of the desirable components in pastures,but whether grazing is rested or strategically applied depends on the management goal,sizes of populations of the IAP and more desirable species,and climatic and edaphic conditions.Conclusions:Based on our findings,we integrated these relationships to develop a testable framework for managing IAPs with strategic grazing that considers both the current state of the plant community and the desired future state—i.e.the application of the principles behind reclamation,rehabilitation,restoration or all three—over time. | Jennifer Firn Jodi N Price Ralph DB Whalley | 2013 | Ecological Processes2013，2，1： | 2 |
| 4 | Smac is required for cytochrome C - induced apoptosis in prostate cancer LNCaP cells 显示文摘 | Carson JP Behnam M Jennifer N | 2002 | Cancer Research2002，62，： | 1 |
| 5 | Mobile Ad Hoc networking:Imperatives and challenges显示文摘 | Chlamtac I Conti M Jennifer J N Liu | 2003 | Ad Hoc Networks2003，，1： | 1 |
| 6 | Sedative and anxiolytic effects of zopiclone's enantiomers and metabolite 显示文摘 | Rene Haskew Jennifer Wacker | 2001 | European Journal of Pharmacology2001，415，： | 1 |
| 7 | Demographic trend in social work over a quarter century in an increasingly female profession 显示文摘 | Robert S Jennifer N M Gan L | 2008 | Social Work2008，53，2： | 1 |
| 8 | β-Adrenergic receptor activation during distinct patterns of stimulation critically modulates the PKA-dependence of LTP in the mouse hippocampus 显示文摘 | Jennifer N Gelinas Gustavo Tenorio Neal Lemon | 2008 | Learn Mem2008，15，5： | 1 |
| 9 | Use of supplementary cementing materials to increase the resistance to chloride ion penetration of concrete cured at elevated temperatures显示文摘 | RACHEL J D CHRIS A F JENNIFER N | 1994 | ACI Materials Journal1994，91，1： | 1 |
| 10 | Stroke sur- vivor and informal caregiver perceptions of post-stroke depressive symptoms显示文摘 | N Jennifer Klinedinst Sandra B Dunbar Patricia C Clark | 2012 | J Neurosei Nurs2012，44，2： | 1 |
| 11 | Bacterocins:safe,natural antimicrobials for food preservation显示文摘 | Jennifer C Thomas J M Ingolf F N | 2001 | International Journal of Food Microbiology2001，71，： | 1 |
| 12 | Therapist on Functional Analysis and Setting Influences Outcomes 显示文摘 | Thomason - Sassi Jessica L Iwata Brian A Fritz Jennifer N | 2013 | Journal of Applied Behavior Analysis2013，，46： | 1 |
| 13 | Scandals, Media and Good Governance in China and Kenya显示文摘 | Jonathan Hassid Jennifer N Brass | 2015 | Journal of Asian and African Studies2015，50，3： | 1 |
| 14 | Room temperature Young's modulus, shear modulus, Poisson's ratio and hardness of PbTe-PbS thermoelectric materials 显示文摘 | Jennifer E N Case E D Khabir K N | 2010 | Materials Science and Engineering: B2010，170，13： | 1 |
| 15 | Classical swine fever virus diversity and evolution显示文摘 | Paul L Georgina I Jennifer N | 1996 | J Gen Virol1996，77，： | 1 |
| 16 | Sedative and anxiolytic effects of zopiclone's enantiomers and metabolite 显示文摘 | JEFFREY N RENE H JENNIFER W | 2001 | Eur J Pharm Sci2001，415，23： | 1 |
| 17 | Short-term sprint interval training inereases insulin sensitivity in healthy adults but does not affeet the thermogenie response to β-adrenergie stimulation 显示文摘 | Jennifer C Richards Tyler K Johnson Jessica N Kuzma | 2010 | The Journal of Physiology2010，588，15： | 1 |
| 18 | Reference genome sequence of the model plant Setaria显示文摘 | Jeffrey L Bennetzen Jeremy Schmutz Hao Wang RyanPercifield Jennifer Hawkins Ana C Pontaroli Matt Estep Liang Feng Justin N Vaughn Jane Grimwood JerryJenkins Kerrie Barry Erika Lindquist Uffe Hellsten Shweta Deshpande Xuewen Wang Xiaomei Wu ThereseMitros Jimmy Triplett Xiaohan Yang Chu-Yu Ye Margarita Mauro-Her-rera Lin Wang Pinghua Li ManojSharma Rita Sharma Pamela C Ronald Olivier Panaud Elizabeth A Kellogg Thomas P Brutnell Andrew NDoust Gerald A Tuskan Daniel Rokhsar Katrien MDevos | 2012 | Nature Biotechnology2012，，30： | 1 |
| 19 | What Influences IT Ethical Behavior Intentions: Planned Behavior, Reasoned Action, Perceived Impor- tance, or Individual Characteristics? 显示文摘 | Lori N K Leonard Timothy Paul Cronan Jennifer Kreie | 2004 | Information & Management2004，，42： | 1 |
| 20 | Bacteriocins: safe, natural antimicrobials for food preservation显示文摘 | JENNIFER C THOMAS J M INGOLF F N | 2001 | lnternat J Food Micro biol2001，71，1： | 1 |
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