维普中文期刊产品整合服务
21篇 您的检索式:作者名="Jennings SA"
    题名 作者 年代 出处 被引量
1Computational Prediction of Micro RNAs from Toxoplasma gondii Potentially Regulating the Hosts' Gene Expression显示文摘Micro RNAs(mi RNAs) were discovered two decades ago, yet there is still a great need for further studies elucidating their genesis and targeting in different phyla. Since experimental discovery and validation of mi RNAs is difficult, computational predictions are indispensable and today most computational approaches employ machine learning. Toxoplasma gondii, a parasite residing within the cells of its hosts like human, uses mi RNAs for its post-transcriptional gene regulation. It may also regulate its hosts' gene expression, which has been shown in brain cancer. Since previous studies have shown that overexpressed mi RNAs within the host are causal for disease onset, we hypothesized that T. gondii could export mi RNAs into its host cell. We computationally predicted all hairpins from the genome of T. gondii and used mouse and human models to filter possible candidates. These were then further compared to known mi RNAs in human and rodents and their expression was examined for T. gondii grown in mouse and human hosts, respectively. We found that among the millions of potential hairpins in T. gondii, only a few thousand pass filtering using a human or mouse model and that even fewer of those are expressed. Since they are expressed and differentially expressed in rodents and human, we suggest that there is a chance that T. gondii may export mi RNAs into its hosts for direct regulation.Müs?erref Duygu Saar Caner Bagc? Jens Allmer 2014Genomics, Proteomics & Bioinformatics2014,12,5:1
2Nursing student perceptions about disaster nursing显示文摘Jennings SA Ffiseh N Wing S 0,,03:1
3Cefazolin Tolerance Does Not Predict Ceftriaxone Hypersensitivity: Unique Side Chains Precipitate Anaphylaxis 显示文摘Poston SA Jennings HR Poe KL 2004Phanna~otherapy2004,24,5:1
4White-coat hypertension and autonomic nervous system dysregulation 显示文摘Neumann SA Jennings JR Muldoon MF 2005Am J Hypertens2005,18,51:1
5Cefazolin tolerance does not predict ceftriaxone hypersensitivity: unique side chains precipitate anaphylaxis 显示文摘Poston SA Jennings HR Poe KL 2004Pharmacotherapy2004,24,5:1
6The saline dilution test-a preoperative predictor of DVT 显示文摘Heather BP Jennings SA Greenhalgh RM 1980Br J Surg1980,67,1:1
7Terlipressin:vasopressin analog and novel drug for septic shock显示文摘Pesaturo AB Jennings HR Voils SA 2006Ann Pharmacother2006,40,12:1
8White-coat hypertension and autonomic nervous system dysregulation显示文摘Neumann SA Jennings JR Muldoon MF 2005Am J hypertens2005,18,:1
9Cefazolin tolerance does not predict ceftriaxone hypersensitivity:unique side chains precipitate anaphylaxis显示文摘Poston SA Jennings HR Poe KL 2004Pharmacotherapy2004,24,5:1
10Therapeutic vaccination against HSV-2:influence of vaccine formulation on immune responses and protection in mice显示文摘Mohamedi SA Heath AW Jennings R 2000Vaccine2000,18,17:1
11Guest Editorial: Entrepreneurship and the Acquisition of Dynamic Organizational Capabilities显示文摘Zahra SA Kuratko D F Jennings D F 1999Entrepreneurship Theory and Practice1999,,:1
12The Natural History of the syndrome of rimary progressive pfreezing gait 显示文摘Factor SA Jennings DL Molho ES 2002Arch Neurol2002,59,:1
13The natural history of the syndrome of primary progressive freezing gait 显示文摘Factor SA Jennings DL Molho ES 2002Archives of neurology2002,59,:1
14The natural history of the syndrome of primary progressive freezing gait显示文摘Factor SA Jennings DL Molho ES 2002Arch Neurol2002,59,:1
15Nursing students'perceptions about disaster nursing显示文摘Jennings SA Frisch N Wing S 0,,3:1
16Molecular detection of tumor cells in bronehoalveolar lavage fluid from patients with early stage lung cancer显示文摘Ahrendt SA Chow JT Xu LH Yang SC Eisenberger CF Esteller M Herman JG Wi L Decker PA Jen J Sidransky D 1999J Natl Cancer Inst1999,91,4:1
17The natural history of the primary progressive freezing gait显示文摘Factor SA Jennings DL Molho ES 0,,:1
18The natural history of the syndrome of primary progressive freezing gait显示文摘Factor SA Jennings DL Molho ES 2002Arch Neurol2002,59,11:1
19Terlipressin: vasopressin analog and novel drug for septic shock 显示文摘Pesaturo AB Jennings HR Voils SA 2006Ann Pharmacother2006,40,12:1
20Nursing studentsy perceptions about disastemursing 显示文摘Jennings SA Frisch N Wing S 2005Disaster Manag Response2005,3,3:1
返回顶部 每页显示:
共2页 首页 上一页 第1页 下一页 末页 /2 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费