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| 1 | Management of early gastrointestinal neuroendocrine neoplasms显示文摘Neuroendocrine neoplasms (NENs) of the stomach, duo- denum, appendix or rectum that are small (≤ 1 cm) and well differentiated can be considered 'early' tumors, since they generally have a (very) good prognosis. In the new WHO classification of 2010, these neoplasms are called neuroendocrine tumors/ carcinoids (NETs), grade (G) 1 or 2, and distinguished from poorly differentiated neuroendocrine carcinomas (NECs), G3. NETs are increasing, with a rise in the age-adjusted incidence in the U.S.A. by about 700 % in the last 35 years. Improved early detection seems to be the main reason for these epidemiological changes. Both the better generalavailability of endoscopy, and imaging techniques, have led to a shift in the discovery of smaller-sized (≤ 10-20 mm) intestinal NETs/carcinoids and earlier tumor stages at diagnosis. Endoscopic screening is therefore effective in the early diagnosis, not only of colorectal adenocarcinomas, but also of NETs/carcinoids. Endoscopic removal, followed up with endoscopic surveillance is the treatment of choice in NETs/carcinoids of the stomach, duodenum and rectum that are ≤ 10 mm in size, have a low proliferative activity (G1), do not infiltrate the muscular layer and show no angioinvasion. In all the other intestinal NENs, optimal treatment generally needs surgery and/or medical therapy depending on type, biology and stage of the tumor, as well as the individual situation of the patient. | Hans Scherübl Robert T Jensen Guillaume Cadiot Ulrich Stlzel Günter Klppel | 2011 | World Journal of Gastrointestinal Endoscopy2011,3,7: | 13 |
| 2 | Neuroendocrine tumors of the small bowels are on the rise:Early aspects and management显示文摘Neuroendocrine tumors of the small bowel are on the rise. In the US they have increased by 300%-500% in the last 35 years. At the same time their prognosis is much improved. Today,most neuroendocrine tumors (NETs) of the duodenum are detected 'incidentally' and therefore recognized at an early stage. Duodenal NETs which are well differentiated,not larger than 10 mm and limited to the mucosa/submucosa can be endoscopically resected. The management of duodenal NETs ranging between 10 and 20 mm needs an interdisciplinary discussion. Endoscopic ultrasound is the method of choice to determine tumor size and depth of infiltration. Surgery is recommended for well-differentiated duodenal NET tumors greater than 20 mm,for localized sporadic gastrinomas (of any size) and for localized poorly differentiated NE cancers. Surgery is recommended for any ileal NET. Advanced ileal NETs with a carcinoid syndrome are treated with longacting somatostatin analogs. This treatment significantly improves (progression-free) survival in patients with metastatic NETs of the ileum. For optimal NET management,tumor biology,type,localization and stage of the neoplasm,as well as the patient's individual circumstances have to be taken into account. | Hans Scherbl Robert T Jensen Guillaume Cadiot Ulrich Stlzel Gnter Klppel | 2010 | World Journal of Gastrointestinal Endoscopy2010,2,10: | 10 |
| 3 | Neuroendocrine tumors of the stomach (gastric carcinoids) are on the rise: small tumors, small problems?显示文摘 | H. Scherübl G. Cadiot R. Jensen T. R?sch U. St?lzel G. Kl?ppel | 2010 | Endoscopy2010,,08: | 3 |
| 4 | Neuroendocrine tumors of the stomach (gastric carcinoids) are on the rise: small tumors, small problems?显示文摘 | H. Scherübl G. Cadiot R. Jensen T. R?sch U. St?lzel G. Kl?ppel | 2010 | Endoscopy2010,,08: | 1 |
| 5 | Management of acute cerebellar atroke显示文摘 | Jensen MB St Louis EK | | 0,,04: | 1 |
| 6 | Pelvic floor muscle injuries 6 weeks post partum—an intra‐ and inter‐rater study显示文摘 | Jette St?r‐Jensen Franziska Siafarikas Gunvor Hilde Ingeborg H. Br?kken Kari B? Marie Ellstr?m Engh | 2013 | Neurourol Urodyn2013,,7: | 1 |
| 7 | Management of acute cerebellar stroke显示文摘 | Jensen MB St Louis EK | 2005 | Arch Neurol2005,624,: | 1 |
| 8 | Management of acute cerebellar stroke 显示文摘 | Jensen MB St Louis EK | 2005 | Archueuor2005,62,4: | 1 |
| 9 | Management of acute cerebellar stroke显示文摘 | Jensen MB St Louis EK | 2005 | Arch Neurol2005,62,4: | 1 |
| 10 | Neuroendocrine tumors of the stomach (gastric carcinoids) are on the rise: small tumors, small problems?显示文摘 | H. Scherübl G. Cadiot R. Jensen T. R?sch U. St?lzel G. Kl?ppel | 2010 | Endoscopy2010,,08: | 1 |
| 11 | Management of acute cerebellar stroke显示文摘 | Jensen MB St Louis EK | 2005 | Arch Neurol2005,62,4: | 1 |
| 12 | Renal inflammatory myofibroblastic tumor: a rare tumor indistinguishable from renal cell carcinoma-report of two cases 显示文摘 | Heerwagen ST Jensen C Bagi P | 2007 | Acta Radiol2007,48,10: | 1 |
| 13 | Management of acute cerebellar stroke显示文摘 | Jensen MB St Louie EK | 2005 | Arch Neurol2005,62,4: | 1 |
| 14 | Image guidance for brain metastases resec- tion显示文摘 | Garber ST Jensen RL | 2012 | Surg Neurol Int2012,3,2: | 1 |
| 15 | Management of acute cerebellar stroke 显示文摘 | Jensen MB St Louis EK | 2005 | Arch Neurol2005,62,4: | 1 |
| 16 | Image guidance for brain metastases resection 显示文摘 | Garber ST Jensen RL | 2012 | Surg Neurol Int2012,32,: | 1 |
| 17 | The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis显示文摘 | Eichenberger P Fujita M Jensen ST | 2004 | PLoS Biology2004,2,10: | 1 |
| 18 | Consensus statements and recommended clinical procedures regarding surgical techniques 显示文摘 | Chen ST Beagle J Jensen SS | 2009 | Int J Oral Maxillofac Implants2009,,: | 1 |
| 19 | Management of acute cerebellar stroke显示文摘 | Jensen MB St Louis EK | 2005 | Arch Neurol2005,62,4: | 1 |
| 20 | Doppler tissue ima-ging is an independent predictor of outcome in patients with ST- segment elevation myocardial infarction treated with primary per cutaneous coronary intervention 显示文摘 | Biering ST Jensen JS Pedersen S et aI | 2014 | J Am Soc Echocardiogr2014,27,3: | 1 |