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4篇 您的检索式：作者名="Jeremy Lynch"

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		题名	作者	年代	出处	被引量
	1	Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation.	Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon	2012	World Journal of Gastrointestinal Oncology2012，4，5：	5
	2	Risk management in radiology departments显示文摘Medical imaging and interventional radiology sustained prompt changes in the last few years, mainly as aresult of technology breakthroughs, rise in workload, deficit in workforce and globalization. Risk is considered to be the chance or possibility of incurring loss or of a negative event happening that may cause injury to patients or medical practitioners. There are various causes of risks leading to harm and injury in radiology departments, and it is one of the objectives of this paper to scrutinize some of the causes. This will drive to consideration of some of the approaches that are used in managing risks in radiology. This paper aims at investigating risk management in radiology, and this will be achieved through a thorough assessment of the risk control measures that are used in the radiology department. It has been observed that the major focus of risk management in such medical setting is to reduce and eliminate harm and injury to patients through integration of various medical precautions. The field of Radiology is rapidly evolving due to technology advances and the globalization of healthcare. This ongoing development will have a great impact on the level of quality of care and service delivery. Thus, risk management in radiology is essential in protecting the patients, radiologists, and the medical organization in terms of capital and widening of the reputation of the medical organization with the patients.	Horea Craciun Kshitij Mankad Jeremy Lynch	2015	World Journal of Radiology2015，7，6：	1
	3	Hyperplastic Polyposis Syndrome: Phenotypic Presentations and the Role of MBD4 and MYH显示文摘	Elizabeth Chow Lara Lipton Elly Lynch Rebecca D’Souza Clelia Aragona Lindy Hodgkin Gregor Brown Ingrid Winship Melissa Barker Daniel Buchanan Shannon Cowie Steve Nasioulas Desiree du Sart Joanne Young Barbara Leggett Jeremy Jass Finlay Macrae	2006	Gastroenterology2006，，1：	1
	4	Accumulated Clonal Genetic Alterations in Familial and Sporadic Colorectal Carcinomas with Widespread Instability in Microsatellite Sequences显示文摘	Takato Fujiwara Joshua M. Stolker Toshiaki Watanabe Asif Rashid Patti Longo James R. Eshleman Susan Booker Henry T. Lynch Jeremy R. Jass Jane S. Green Hoguen Kim Jin Jen Bert Vogelstein Stanley R. Hamilton	1998	The American Journal of Pathology1998，，4：	1

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