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| 1 | Abernethy syndrome in Slovenian children: Five case reports and review of literature显示文摘BACKGROUND Abernethy syndrome is a congenital vascular anomaly in which the portal blood completely or partially bypasses the liver through a congenital portosystemic shunt.Although the number of recognized and reported cases is gradually increasing,Abernethy syndrome is still a rare disease entity,with an estimated prevalence between 1 per 30000 to 1 per 50000 cases.With this case series,we aimed to contribute to the growing knowledge of potential clinical presentations,course and complications of congenital portosystemic shunts(CPSS)in children.CASE SUMMARY Five children are presented in this case series:One female and four males,two with an intrahepatic CPSS and three with an extrahepatic CPSS.The first patient,who was diagnosed with an intrahepatic CPSS,presented with gastrointestinal bleeding,abdominal pain and hyperammonaemia at six years of age.He underwent a percutaneous embolization of his shunt and has remained asymptomatic ever since.The second patient presented with direct hyperbilirubinemia in the neonatal period and his intrahepatic CPSS later spontaneously regressed.The third patient had pulmonary hypertension and hyperammonaemia due to complete portal vein agenesis and underwent liver transplantation at five years of age.The fourth patient was diagnosed immediately after birth,when evaluated due to another congenital vascular anomaly,and the last patient presented as a teenager with recurrent bone fractures associated with severe osteoporosis.In addition,the last two patients are characterised by benign liver nodules;however,they are clinically stable on symptomatic therapy.CONCLUSION Abernethy syndrome is a rare anomaly with diverse clinical features,affecting almost all organ systems and presenting at any age. | Jerneja Pecek Petja Fister Matjaz Homan | 2020 | World Journal of Gastroenterology2020，26，37： | 6 |
| 2 | Potential of Zimbabwean commercial probiotic products and strains of Lactobacillus plantarum as prophylaxis and therapy against diarrhoea caused by Escherichia coli in children显示文摘Objective: To evaluate the potential of commercial fermented products sold in the country,and strains of Lactobacillus plantarum(L,plantarum)as prophylaxis and therapy against diarrhoea in children,Methods: The antimicrobial potential of cultures of lactobacilli enriched from 4 Zimbabwean commercial food/beverage products: Dairibord Lacto sour milk(DLSM),Probrand sour milk(PSM),Kefalos Vuka cheese(KVC) and Chibuku opaque beer(COB); and four strains of L,plantarum obtained from Balkan traditional cheeses against clinical strains of Escherichia coli(E,coli) was assayed using the well diffusion method,Three commercial paediatric antidiarrhoeal drug products: Biogaia(BG),Prolife(PL) and Probio Junior(PJ) and a mutant strain of E,coli [strain 11105(ATCC)- a vitamin B-12 auxotroph and penicillin G acylase-producing strain] were used as controls,An agar diffusion assay and a competitive exclusion assay were carried out on Mueller Hinton agar,Results: Crude cultures of putative lactobacillus strains obtained from Zimbabwean dairy products(Probrand sour milk,Kefalos Vuka vuka cheese and Chibuku opaque beer) had significantly higher antimicrobial activities against clinical strains of E,coli than strains of L,plantarum isolated from Balkan cheeses(CLP1,CLP2 or CLP3) and crude microbial cultures from commercial paediatric probiotic products(BG,PJ and PL) of a culture of Lactobacillus rhamnosus LGG(P<0.05),Conclusions: The putative Lactobacilli from four commercial Zimbabwean dairy products(Probrand sour milk,Kefalos Vuka vuka cheese and Chibuku opaque beer),and three strains of L,plantarum from Balkan cheeses(CLP1,CLP2 or CLP3) exhibited high antibacterial activities that can be harnessed to control paediatric diarrhoea that is caused by pathogenic strains of E,coli,Studies to characterise the probiotic potential of the live cultures in the products and the new strains of L,plantarum are underway. | Walter Chingwaru Jerneja Vidmar | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，1： | 5 |
| 3 | Variants in the Netrin-1 Receptor UNC5C Prevent Apoptosis and Increase Risk of Familial Colorectal Cancer显示文摘 | Marie–May Coissieux Jerneja Tomsic Marie Castets Heather Hampel Sari Tuupanen Nadine Andrieu Ilene Comeras Youenn Drouet Christine Lasset Sandya Liyanarachchi Laetitia Mazelin Alain Puisieux Jean–Christophe Saurin Jean–Yves Scoazec Qing Wang Lauri Aaltone | 2012 | Gastroenterology2012，，6： | 2 |
| 4 | Extxaction of phenolic compounds from green walnut fa'uits in different solvents 显示文摘 | Jerneja JAKOPIC Robert VEBERIC Franci STAMPAR | 2009 | Acta Agricultue Slovenica2009，93，1： | 1 |
| 5 | The influence of exposure to light on the phenolic content of ' Fuji' apple 显示文摘 | Jerneja Jakopic Franci Stampar Robert Veberic | 2009 | Scientia Horticulturae2009，123，： | 1 |
| 6 | A new amoxicillin/clavulanate therapeutic system- Preparation, in vitro and pharmacokinet- ic evaluation 显示文摘 | Janez Kere Jerneja Opara | 2007 | Intern J Pharmaceutic2007，335，12： | 1 |
| 7 | Principal Directions of Synthetie Exact Filters for Robust Real-Time Eye Localization 显示文摘 | VITOMIR S JERNEJA Z G NIKOLA P | 2011 | Biometrics and ID Management Lecture Notes in Computer Science2011，6583，： | 1 |
| 8 | 显示文摘 | John G F Andreja B Jerneja G | 2008 | J Eur Ceram Soc2008，28，： | 1 |
| 9 | Colon and Endometrial Cancers with Mismatch Repair Deficiency can Arise from Somatic, Rather Than Germline, Mutations显示文摘 | Sigurdis Haraldsdottir Heather Hampel Jerneja Tomsic Wendy L. Frankel Rachel Pearlman Albert de la Chapelle Colin C. Pritchard | 2014 | Gastroenterology2014，，： | 1 |
| 10 | Mammalian cell cultures as models for Mycobacterium tuberculosis-human immunodeficiency virus(HIV) interaction studies:A review显示文摘Mycobacterium tuberculosis(MTB) and human immunodeficiency virus(HIV) co-infections have remained a major public health concern worldwide,particularly in Southern Africa.Yet our understanding of the molecular interactions between the pathogens has remained poor,primarily due to lack of suitable preclinical models for such studies.We reviewed the use,this far,of mammalian cell culture models in HIV-MTB interaction studies.Studies have described the use of primary human cell cultures,including monocyte-derived macrophage(MDM) fractions of peripheral blood mononuclear cell(PBMC),alveolar macrophages(AM),cell lines such as the monocyte-derived macrophage cell line(U937),T lymphocyte cell lines(CEMx174,ESAT-6-specific CD4+ T-cells) and an alveolar epithelial cell line(A549) and special models such as stem cells,three dimensional(3D) or organoid cell models [including a blood-brain barrier(BBB) cell model] in HIV-MTB interaction studies.The use of cell cultures from other mammals,including:mouse cell lines [macrophage cell lines RAW 264.7 and J774.2,fibroblast cell lines(NIH 3T3,C3 H clones),embryonic fibroblast cell lines and T-lymphoma cell lines(S1A.TB,TIMI.4 and R1.1)]; rat(T cells:Rat2,RGE,XC and HH16,and alveolar cells:NR8383) and primary guinea pigs derived AMs,in HIV-MTB studies is also described.Given the spectrum of the models available,cell cultures offer great potential for host-HIV-MTB interactions studies. | Walter Chingwaru Richard H.Glashoff Jerneja Vidmar Petrina Kapewangolo Samantha L.Sampson | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，9： | 0 |
| 11 | Dishwashers provide a selective extreme environment for human-opportunistic yeast-like fungi显示文摘Urban life has led to the creation of human-made environments that,from a microbiological perspective,provide extreme life conditions.Certain non-ubiquitous microorganisms such as thermophilic members of the black yeast genus Exophiala are enriched within these habitats for which no counterpart is known in nature.Dishwashers consistently accumulate a number of specific black,white and red yeasts on the rubber seals of doors and in stagnant water at the interior.Several of these yeasts are primarily known as agents of human opportunistic infections.In this review,the literature data are supported by a screening study involving 937 households in 15 cities in Turkey.Fungi were detected in 230 samples(24.5%).Using rDNA sequencing,the prevalent species were identified as Exophiala dermatitidis(n=116),Candida parapsilosis(n=44),E.phaeomuriformis(n=35),Magnusiomyces capitatus(n=22),Rhodotorula mucilaginosa(n=15),and C.lusitaniae(n=14).The possible role of dishwashers in transmitting disease is discussed. | Ramazan Gümral BetilÖzhak-Baysan Ayşegül Tümgör Mehmet Ali Saraçlı Şinasi Taner Yıldıran Macit Ilkit Jerneja Zupančič Monika Novak-Babič Nina Gunde-Cimerman Polona Zalar GSybren de Hoog | 2016 | Fungal Diversity2016，，1： | 0 |
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