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| 1 | Treatment of laryngopharyngeal reflux disease: A systematic review显示文摘BACKGROUNG For a long time,laryngopharyngeal reflux disease(LPRD)has been treated by proton pump inhibitors(PPIs)with an uncertain success rate.AIM To shed light the current therapeutic strategies used for LPRD in order to analysis the rationale in the LPRD treatment.METHODS Three authors conducted a PubMed search to identify papers published between January 1990 and February 2019 about the treatment of LPRD.Clinical prospective or retrospective studies had to explore the impact of medical treatment(s)on the clinical presentation of suspected or confirmed LPRD.The criteria for considering studies for the review were based on the population,intervention,comparison,and outcome framework.RESULTS The search identified 1355 relevant papers,of which 76 studies met the inclusion criteria,accounting for 6457 patients.A total of 64 studies consisted of empirical therapeutic trials and 12 were studies where authors formally identified LPRD with pH-monitoring or multichannel intraluminal impedance-pH monitoring(MII-pH).The main therapeutic scheme consisted of once or twice daily PPIs for a duration ranged from 4 to 24 wk.The most used PPIs were omeprazole,esomeprazole,rabeprazole,lansoprazole and pantoprazole with a success rate ranging from 18%to 87%.Other composite treatments have been prescribed including PPIs,alginate,prokinetics,and H2 Receptor antagonists.CONCLUSION Regarding the development of MII-pH and the identification of LPRD subtypes(acid,nonacid,mixed),future studies are needed to improve the LPRD treatment considering all subtypes of reflux. | Jerome R Lechien Francois Mouawad Maria R Barillari Andrea Nacci Seyyedeh Maryam Khoddami Necati Enver Sampath Kumar Raghunandhan Christian Calvo-Henriquez Young-Gyu Eun Sven Saussez | 2019 | World Journal of Clinical Cases2019，7，19： | 9 |
| 2 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015，5，1： | 6 |
| 3 | Immunogenetic phenotypes in inflammatory bowel disease显示文摘当前接受的 etiopathogenic 假设建议长期的肠的发炎和煽动性的肠疾病(IBD ) 的相关全身的表明特征由于对居民钠的过分好攻击或病理学的有免疫力的回答细菌的成分。预先安排的因素是粘膜免疫者回答或障碍功能的基因 dysregulation,与环境刺激触发的发作。这些因素和他们的相互作用可以也是疾病显型和疾病前进的重要决定因素。免疫的出现基因显型把支持借给不同免疫者处理的危险性基因调整的建议假设,由钠抗原开车,表示了接着在 IBD 影响临床的显型的同样特定的有免疫力的显型病人。 | Maria C Dubinsky Kent Taylor Stephan R Targan Jerome I Rotter | 2006 | World Journal of Gastroenterology2006，12，23： | 4 |
| 4 | Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal Cancer显示文摘 | Douglas K Rex John H Bond Sidney Winawer Theodore R Levin Randall W Burt David A Johnson Lynne M Kirk Scott Litlin David A Lieberman Jerome D Waye James Church John B Marshall Robert H Riddell | 2002 | The American Journal of Gastroenterology2002，，6： | 3 |
| 5 | Environmental impacts of steel slag reused in road construction: A crystallographic and molecular (XANES) approach显示文摘 | Perrine Chaurand Jerome Rose Valérie Briois Luca Olivi Jean-Louis Hazemann Olivier Proux Jérémie Domas Jean-Yves Bottero | 2006 | Journal of Hazardous Materials2006，，3： | 2 |
| 6 | Stability of fruit quality traits in diverse watermelon cultivars tested in multiple environments显示文摘Lycopene is a naturally occurring red carotenoid compound that is found in watermelon.Lycopene has antioxidant properties.Lycopene content,sugar content and hollowheart resistance are subject to significant genotype×environment interaction(G×E),which makes breeding for these fruit quality traits difficult.The objectives of this study were to(i)evaluate the influence of years and locations on lycopene content,sugar content and hollowheart resistance for a set of watermelon genotypes,and(ii)identify genotypes with high stability for lycopene,sugar,and hollowheart resistance.A diverse set of 40 genotypes was tested over 3 years and 8 locations across the southern United States in replicated,multi-harvest trials.Lycopene was tested in a subset of 10 genotypes.Data were analyzed using univariate and multivariate stability statistics(BLUP-GGE biplot)using SASGxE and RGxE programs.There were strong effects of environment as well as G×E interaction on watermelon quality traits.On the basis of stability measures,genotypes were classified as stable or unstable for each quality trait.'Crimson Sweet'is an inbred line with high quality trait performance as well as trait stability.'Stone Mountain','Tom Watson','Crimson Sweet'and'Minilee'were among the best genotypes for lycopene content,sugar content and hollowheart resistance.We developed a stability chart based on marketable yield and average ranking generated from different stability measures for yield attributes and quality traits.The chart will assist in choosing parents for improvement of watermelon cultivars.See http://cuke.hort.ncsu.edu/cucurbit/wmelon/wmelonmain.html. | Mahendra Dia Todd C Wehner Penelope Perkins-Veazie Richard Hassell Daniel S Price George E Boyhan Stephen M Olson Stephen R King Angela R Davis Gregory E Tolla Jerome Bernier Benito Juarez | 2016 | Horticulture Research2016，3，1： | 2 |
| 7 | Risk actors for HPV infection and cervical cancer among un - crcened women in a high - risk rural area of China显示文摘 | Fang - hui Zhao Michele R Forman Jerome Belinson | 2006 | Int Jancer2006，118，2： | 1 |
| 8 | Quantitative stability of DNA after extended storage of clinical specimens as determined by real-time PCR显示文摘 | JEROME K R HUANG M L WALD A | 2002 | Journal of Clinical Mi-crobiology2002，40，7： | 1 |
| 9 | Anionic polymerization of methacrylic monomers: Characterization of the propagating species显示文摘 | ZUNE C JEROME R | 1999 | Progress in Polymer Science1999，24，： | 1 |
| 10 | Molecular analysis of bacterial pathogens in otitis media with effusion显示文摘 | POST J C PRESTON R A JEROME J A | 1995 | JAMA1995，273，： | 1 |
| 11 | Mul- tialternative decision field theory: a dynamic connec- tionist model of decision making显示文摘 | ROBERT M R JEROME R B JAMES T T | 2001 | Psychological Review2001，108，2： | 1 |
| 12 | Fifty Years of Orbit Determination 显示文摘 | Jerome R Vetter | 2007 | Development of Modem Asttodynamics Methods (S0270-5214)2007，27，3： | 1 |
| 13 | A change in the premitotic period of the cell cycle is associated with bradyzoite differentiation in Toxoplasma gondii显示文摘 | Jay R Radke Michael N Guerini Maria Jerome | 2003 | Mol Biochem Parasitol2003，131，： | 1 |
| 14 | Characterization and control of interfaces in emulsified incompatible polymer blends 显示文摘 | Fayt R Jerome R Teyssie P | 1987 | Polym Eng Sci1987，27，： | 1 |
| 15 | Estimation of organic and inorganic matter in inland waters:optical cross sections of Lakes Ontario and Ladoga显示文摘 | Bukata R P Jerome J H Kondratyev K Y | 1991 | J Great Lakes Res1991，17，： | 1 |
| 16 | 查看详情显示文摘 | Labaye D.E Jerome C Geskin V.M Louette P Lazzaroni R Martinot L Jerome R | | 0，，： | 1 |
| 17 | Apolipoprotein A-I structural organization in high-density lipoproteins isolated from human plasma 显示文摘 | Huang R Silva RA Jerome WG | 2011 | Nat Struct Mol Biol2011，18，4： | 1 |
| 18 | Comparison of free-breathing with navigator-controlled acquisition regimes in abdominal diffusion-weighted magnetic resonance images: effect on ADC and IVIM statistics显示文摘 | Jerome N P Orton M R D'Arcy J A | 2014 | J Magn Reson Imaging2014，39，1： | 1 |
| 19 | Polysiloxane-based activators in the anionic block copolymerization of ε-caprolactam显示文摘 | Lefebvre P M Jerome R Teyssié P | 1982 | DieMakromolekulare Chemie1982，183，10： | 1 |
| 20 | Applications of supercritical fluids in the controlled release of drugs supercrit显示文摘 | Tom J W Debenedetti P G Jerome R | 1994 | Fluids1994，，7： | 1 |
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