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| 1 | Inferring microbial interaction networks based on consensus similarity network fusion显示文摘With the rapid accumulation of high-throughput metagenomic sequencing data,it is possible to infer microbial species relations in a microbial community systematically.In recent years,some approaches have been proposed for identifying microbial interaction network.These methods often focus on one dataset without considering the advantage of data integration.In this study,we propose to use a similarity network fusion(SNF)method to infer microbial relations.The SNF efficiently integrates the similarities of species derived from different datasets by a cross-network diffusion process.We also introduce consensus k-nearest neighborhood(Ck-NN)method instead of k-NN in the original SNF(we call the approach CSNF).The final network represents the augmented species relationships with aggregated evidence from various datasets,taking advantage of complementarity in the data.We apply the method on genus profiles derived from three microbiome datasets and we find that CSNF can discover the modular structure of microbial interaction network which cannot be identified by analyzing a single dataset. | JIANG XingPeng HU XiaoHua | 2014 | Science China(Life Sciences)2014，57，11： | 3 |
| 2 | A new DNA algorithm to solve graph coloring problem显示文摘Using a small quantity of DNA molecules and little experimental time to solve complex problems successfully is a goal of DNA computing. Some NP-hard problems have been solved by DNA computing with lower time complexity than conventional computing. However, this advantage often brings higher space complexity and needs a large number of DNA encoding molecules. One example is graph coloring problem. Current DNA algorithms need exponentially increasing DNA encoding strands with the growing of problem size. Here we propose a new DNA algorithm of graph coloring problem based on the proof of four-color theorem. This algorithm has good properties of needing a relatively small number of operations in polynomial time and needing a small number of DNA encoding molecules (we need only 6R DNA encoding molecules if the number of regions in a graph is R). | Jiang Xingpeng Li Yin Meng Ya Meng Dazhi | 2007 | Progress in Natural Science:Materials International2007，17，6： | 2 |
| 3 | Identification of the clustering structure in microbiome data by density clustering on the Manhattan distance显示文摘Clustering technology is a method for grouping data points into clusters containing a group of similar data points. In a real dataset such as microbiome data, the data points are presented as profiles or a probability distribution. These data points form the periphery of a cluster, making it difficult to identify the real clustering structure. In this study, we used density clustering on several distance measures to overcome this difficulty. Experiments using a real dataset indicated that the Manhattan distance is an appropriate distance measure for clustering analysis of microbiome data. | Xingpeng JIANG Xiaohua HU Tingting HE | 2016 | Science China(Information Sciences)2016，59，7： | 2 |
| 4 | Direction-of-arrival estimation for uniform circular arrays under small sample size显示文摘With a small number of snapshots, performances of uniform circular array(UCA) root-MUSIC based methods for directionof-arrival(DOA) estimation suffer serious degradation, because the beamspace sample covariance matrix(BSCM) severely deviates from the true one. To solve this problem, an iterative technique is proposed. The proposed technique has two key points: transform array data into beamspace data and construct a BSCM; modify the BSCM repeatedly by removing the residual parts. Meanwhile,error and beamspace leakage associated with the BSCM are investigated. The proposed technique can significantly reduce the error and the beamspace leakage which in turn could improve the performance for DOA estimation. Simulation results are given to illustrate the superiority of the proposed technique for uncorrelated and correlated signals. | Guojun Jiang Xingpeng Mao Yongtan Liu | 2016 | Journal of Systems Engineering and Electronics2016，27，6： | 2 |
| 5 | A non-negative matrix factorization framework for identifying modular patterns in metagenomic profile data显示文摘 | Xingpeng Jiang Joshua S. Weitz Jonathan Dushoff | 2012 | Journal of Mathematical Biology2012，，4： | 1 |
| 6 | The thermal effect in a grazing-incidence slab laser with the novel composite cooling meth od显示文摘 | Chen Zhuo Yan Xingpeng Jiang Xiaoyu | 2009 | Opt Quantum Electron2009，41，9： | 1 |
| 7 | PMU-based fault location using voltage measurements in large transmission networks显示文摘 | Jiang Quanyuan Li Xingpeng Wang Bo | 2012 | IEEE Transactions on Power Delivery2012，27，3： | 1 |
| 8 | Rationale and Study Design for Evaluating the Efficacy and Safety of Intracardiac Echocardiography-Guided Minimal-Fluoroscopy Ablation in Patients with Paroxysmal Atrial Fibrillation:A Non-Inferior,Multi-Center,Prospective Randomized Controlled Trial(PAF-ICE Trial)显示文摘The feasibility and safety of intracardiac echocardiography(ICE)-guided catheter ablation for atrial fibrillation(AF)using a minimal/zero-fluoroscopy approach have recently been reported.This approach helps to reduce ionizing radiation exposure and orthopedic complications resulting from using lead aprons.The objectives of this planned prospective,multicenter randomized controlled trial(RCT)(paroxysmal AF(PAF)-ICE trial;ChiCTR2000033624)are to evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF and the impact on occupational hazards among lab staff.Patients will be randomized in a 1:1 ratio to 2 groups:minimal fluoroscopy group(n=216)and traditional approach group(n=216).In the minimal fluoroscopy group,an ICE catheter will be used for geometry/anatomic construction,transseptal puncture,catheter tracking,and effusion monitoring.Pulmonary vein isolation(PVI)will be performed using an open-irrigated radiofrequency SmartTouch Surround Flow or SmartTouch catheter(Biosense Webster,Diamond Bar,California,USA),and confirmed by a multipolar Lasso or PentaRay catheter(Biosense Webster).In the traditional approach group,an ICE catheter will not be used.Transseptal puncture will be performed under fluoroscopic guidance,with all geometries constructed by mapping the catheters.The primary efficacy endpoint is freedom from AF recurrence(without antiarrhythmic medications)at 12months after ablation.Other endpoints include duration of lead apron use,measures of intra-procedural efficiency,and peri-procedural complications.This RCT will evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF,also evaluate the benefits to lab staff(regarding reducing occupational hazards)related to this“minimal/zero-fluoroscopy”and“leadless”mode. | Ruhong Jiang Xingpeng Liu Jidong Zhang Yu Chen Rui Wang Mengzuo Wu Deyong Long Jia Li Haixiong Wang Jie Fan Weizhu Ju Weili Ge Xu Liu Hai Deng Weijian Wang Pingzhen Yang Ding Li Xiaobo Huang Xiongtao Liu Hailong Tao Paul CZei Roderick Tung Xunzhang Wang Chenyang Jiang | 2021 | Cardiology Discovery2021，1，4： | 1 |
| 9 | Synthesis of Bi_(6)O_(6)(OH)_(3)(NO_(3))_(3)·1.5H_(2)O/ZnO composite material with excellent photocatalytic hydrogen production performance显示文摘The heterojunction effect can effectively improve the separation efficiency of the photocatalyst’s photo-generated electron and hole pairs,thereby greatly improving the photocatalytic hydrogen production performance of the photocatalyst.In this paper,Bi_(6)O_(6)(OH)_(3)(NO_(3))_(3)·1.5H_(2)O(BBN)and ZnO are used to construct and synthesize Bi_(6)O_(6)(OH)_(3)(NO_(3))_(3)·1.5H_(2)O/ZnO(BBN/ZnO)heterojunction photocatalyst.Under UV-vis light irradiation,the BBN/ZnO composite could generate H_(2)with a rate of 28.66μmol·g^(−1)·h^(−1),which is higher than pure BBN(0.92μmol·g^(−1)·h^(−1))and ZnO(6.54μmol·h^(−1)·g^(−1))at around 31.1 and 4.4 times,respectively.Moreover,the experimental results found that the composite still exhibits excellent photocatalytic activity and maintains a high and stable activity in the 12-hour experiment with 3 cycles.The possible mechanism to enhance the photocatalytic behavior is attributed to the expanded light absorption range,reduced surface migration resistance,and inhibited recombination of photo-generated electron and hole pairs. | Lingyi Wang Shichang Sun Ziqing Zhong Qingguang Gong Xingpeng Jiang Weiming Zhou Liwei Wang Ming Lin Zhanhui Yuan | 2021 | International Journal of Smart and Nano Materials2021，12，2： | 0 |
| 10 | A powerful adaptive microbiome-based association test for microbial association signals with diverse sparsity levels显示文摘The dysbiosis of microbiome may have negative effects on a host phenotype.The microbes related to the host phenotype are regarded as microbial association signals.Recently,statistical methods based on microbiome-phenotype association tests have been extensively developed to detect these association signals.However,the currently available methods do not perform well to detect microbial association signals when dealing with diverse sparsity levels(i.e.,sparse,low sparse,non-sparse).Actually,the real association patterns related to different host phenotypes are not unique.Here,we propose a powerful and adaptive microbiome-based association test to detect microbial association signals with diverse sparsity levels,designated as MiATDS.In particular,we define probability degree to measure the associations between microbes and the host phenotype and introduce the adaptive weighted sum of powered score tests by considering both probability degree and phylogenetic information.We design numerous simulation experiments for the task of detecting association signals with diverse sparsity levels to prove the performance of the method.We find that type I error rates can be well-controlled and MiATDS shows superior efficiency on the power.By applying to real data analysis,MiATDS displays reliable practicability too.The R package is available at https://github.com/XiaoyunHuang33/MiATDS. | Han Sun Xiaoyun Huang Lingling Fu Ban Huo Tingting He Xingpeng Jiang | 2021 | Journal of Genetics and Genomics2021，48，9： | 0 |
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