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您的检索式：作者名="Jiangbin Liang"
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| 1 | A botanical medicine dragon’s blood exhibited clinical antithrombosis efficacy similar to low molecular weight heparin显示文摘Deep vein thrombosis(DVT)is a common complication following traumatic fracture with a 0.5%–1%annual incidence.Low molecular weight heparin(LMWH)is the most commonly used anticoagulation drug for DVT prevention,but treatment with LMWH is invasive.Our aim is to compare the antithrombotic effect of dragon’s blood,an oral botanical anticoagulant medicine approved by the Chinese FDA,with LMWH in patients undergoing hip fracture surgery and to explore the molecular mechanisms of anticoagulation treatment.Our study recruited patients and divided them into LMWH and dragon’s blood treatment group.Coagulation index tests,Doppler ultrasound and mRNA sequencing were performed before and after anticoagulation therapy.There was no significant difference in postoperative DVT incidence between the two groups(23.1%versus 15.4%,P=0.694).D-dimer(D-D)and fibrinogen degradation product(FDP)showed significant reductions in both groups after anticoagulation treatments.We identified SLC4A1,PROS1,PRKAR2B and seven other genes as being differentially expressed during anticoagulation therapy in both groups.Genes correlated with coagulation indexes were also identified.Dragon’s blood and LMWH showed similar effects on DVT and produced similar gene expression changes in patients undergoing hip fracture surgery,indicating that dragon’s blood is a more convenient antithrombosis medicine(oral)than LMWH(hypodermic injection). | Jiangbin Liang Song Mei Xiangyu Qiao Wei Pan Yan Zhao Shaohui Shi Yaling Zhai Haizhao Wen Guoping Wu Chengyu Jiang | 2021 | Science China(Life Sciences)2021，64，10： | 4 |
| 2 | Spatial heterogeneity of the economic growth pattern and influencing factors in formerly destitute areas of China显示文摘Accelerating economic growth in formerly destitute areas and narrowing the economic gap with other regions are essential tasks for poverty alleviation in China after 2020.In this study,the spatio-temporal characteristics of economic growth in 14 formerly destitute areas of China were identified.Moreover,the spatial heterogeneity of various influencing factors was analyzed using a geographically weighted regression model.The results were as follows:(1)The economic level of the formerly destitute areas was low,but their economies grew rapidly after 2011,with annual per capita GDP growth of 10.54%until 2018,higher than the national average of 9.14%.Western and southern counties grew faster economically than central and northern counties.(2)The impact of various factors on the economic growth of counties exhibited clear spatial heterogeneity.The influences of secondary industry growth and level of financial development on economic growth were mainly positive,whereas the effects of initial economic level and market location were mainly negative.(3)Six economic growth driving modes were identified for the 14 contiguous destitute areas,among which the secondary industry-driven mode was the most common.The study can serve as a scientific reference for differentiating regional policies. | YIN Jiangbin LI Shangqian ZHOU Liang JIANG Lei MA Wei | 2022 | Journal of Geographical Sciences2022，32，5： | 0 |
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