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| 1 | Activation of Rac1-PI3K/Akt is required for epidermal growth factorinduced PAK1 activation and cell migration in MDA-MB-231 breast cancer cells显示文摘Epidermal growth factor (EGF) may increase cell motility,an event implicated in cancer cell invasion and metastasis.However,the underlying mechanisms for EGF-induced cell motility remain elusive.In this study,we found that EGF treatment could activate Ras-related C3 botulinum toxin substrate 1 (Rac1),PI3K/Akt and p21actived kinase (PAK1) along with cell migration.Ectopic expression of PAK1 K299R,a dominant negative PAK1 mutant,could largely abolish EGF-induced cell migration.Blocking PI3K/Akt signalling with LY294002 or Akt siRNA remarkably inhibited both EGF-induced PAK1 activation and cell migration.Furthermore,expression of dominant-negative Rac1 (T17N) could largely block EGF-induced PI3K/Akt-PAK1 activation and cell migration.Interestingly,EGF could induce a significant production of ROS,and N-acetyl-L-cysteine,a scavenger of ROS which abolished the EGF-induced ROS generation,cell migration,as well as activation of PI3K/Akt and PAK,but not Rac1.Our study demonstrated that EGF-induced cell migration involves a cascade of signalling events,including activation of Rac1,generation of ROS and subsequent activation of PI3K/Akt and PAK1. | Yu Yang Jun Du Zhenzhen Hu Jiaojing Liu Yinhui Tian Yichao Zhu Le Wang Luo Gu | 2011 | The Journal of Biomedical Research2011，25，4： | 3 |
| 2 | An Efficient Extraction-Free Method for Oxidative Desulfurization of Model Fuels Employing Cross-Linked Polyionic Liquid Phosphotungstate Catalysts显示文摘An efficient extraction-free oxidative desulfurization(ODS)process using a series of cross-linked polyionic liquid phosphotungstate(CLPIL-PW)catalysts is reported.The cross-linked PILs were prepared with DVB and 1-n-alkyl-3-vinyl imidazole hydrobromide(alkyl=ethyl,butyl,octyl,dodecyl),and were then assembled with phosphotungstic acid(H_(3)PW_(12)O_(40))to form the catalysts.The CLPIL-PWs have been applied to the oxidative removal of dibenzothiophene(DBT)from model oil with H_(2)O_(2) as an oxidant.The effects of ionic liquid(IL)cationic species,varying the DVB/IL molar ratio in the polymerization process,and varying operating conditions were investigated.The CLPIL-PWs were characterized by inductively coupled plasma(ICP)mass spectrometry,elemental analysis,scanning electron microscopy(SEM),Fourier transform infra-red(FTIR)spectroscopy,X-ray diffraction(XRD),^(13)C and^(31)P nuclear magnetic resonance(NMR)spectroscopy.The polydivinylbenzene-co-1-n-octyl-3-vinyl imidazole phosphotungstate(P(DVB-OVIm)PW)exhibited the highest DBT removal efficiency(99.9%)and remarkable recyclability,and could be reused eight times without reducing its activity.Finally,an extraction-free ODS mechanism is proposed. | Yuan Dandan Zhang Ling Yin Guoqing Wang Yuanyuan Zhang Jiaojing | 2022 | China Petroleum Processing & Petrochemical Technology2022，24，3： | 2 |
| 3 | StudyontheregularityofricechalkinessoccurrenceinthenortheastofChina显示文摘 | JiaoJ(矫江) WangB-L(王伯伦) | | 作物学报0，，： | 1 |
| 4 | Hepatic fibrosis 显示文摘 | JiaoJ Friedman SL Aloman C | 2009 | Curr opin gastmenterol2009，25，： | 1 |
| 5 | Packets Interleaving CCSDS File Delivery Protocol in Deep Space Communication 显示文摘 | JiaoJ GuoQ ZhangQ Y | 2011 | IEEE Aerospace and Electronic Systems Magazine2011，26，2： | 1 |
| 6 | Ultrahigh rate binder-free Na_3V_2(PO_4)_3/carbon cathode for sodium-ion battery显示文摘Sodium ion batteries(SIBs)are very promising for large-scale energy storage in virtue of its high energy density,abundant sodium resources and low environmental impact,etc.However,it is still a big challenge to develop high-performance and durable cathode materials for SIBs.Among different candidate materials,Na_3V_2(PO_4)_3has attracted great attentions due to its high theoretical capacity(117 mAh/g),stable framework structure and excellent ionic conductivity.However,Na_3V_2(PO_4)_3delivers inferior rate capability and cycling stability due to its poor electronic conductivity.In this work,free-standing Na_3V_2(PO_4)_3/carbon nanofiber membranes are synthesized by an electrospinning-sintering route.The sample could deliver excellent cycling capability with specific capacity of 112 mAh/g at 1 C after 250cycles and ultrahigh rate capability with 76.9 mAh/g even at 100 C,which is superior to many state-ofthe-art SIB cathode materials.This can be attributed to the hierarchically distributed Na_3V_2(PO_4)_3crystals in carbon nanofiber network,which possesses outstanding electronic/ionic conductivity and thus leads to an ultrahigh rate capability. | Le Yang Wei Wang Mingxiang Hu Jiaojing Shao Ruitao Lv | 2018 | Journal of Energy Chemistry2018，27，5： | 1 |
| 7 | Product family modeling for mass customization显示文摘 | JIAOJ X TSENG M M DUFFY V G | 1998 | Computers Industry Engineering1998，35，34： | 1 |
| 8 | Developmentofricethrowing-seedlingcultivationtechnique显示文摘 | LiW-M(李文茂) JiaoJ(矫江) | | 现代化农业0，，： | 1 |
| 9 | Phytogenicmounds of four typical shoot architecture species at different slope gradients on the Loess Plateau of China显示文摘 | Du H D JiaoJ Y JiaYF etal | 2013 | Geo- morphology2013，193，7： | 1 |
| 10 | Design for mass customization显示文摘 | TSEN6 M JIAOJ | 1996 | Annala of the CIRP1996，45，1： | 1 |
| 11 | Identification of CD166 as a surface marker for enriching prostate stem/progenitor and cancer initiating cells显示文摘 | JiaoJ Hindoyan A Wang S | 2012 | PLoS One2012，7，42： | 1 |
| 12 | A method to evade silicon backside damage in deep reactive ion etching for anodically bonded glass-silicon structures显示文摘 | MATSUURA T CHABLOZ M JIAOJ | 2001 | Sensors and Actuators2001，89，12： | 1 |
| 13 | Comparative study of laser-induced choroidalneovascularization in rats by paraffin sections, frozen sections andhigh-resolution optical coherence tomography, Graefe's archive for clinical andexperimental ophthalmology显示文摘 | JiaoJ Mo B Wei H | 2013 | Albrecht von Graefes Archiv fur klinische undexperimentelle 0phthalmologie(20132013，3017，： | 1 |
| 14 | Hemangiopericytoma in the vertebral canal of thoracic segments: report of a rare case显示文摘In this paper, we explore the diagnosis and treatment of hemangiopericytoma(HPC). A rare case of HPC in the vertebral canal of thoracic segments is reported, and the clinical features as well as treatment approaches of similar cases in the literature are discussed. In the present case, we operatively resected the tumor and performed postoperative radiation therapy, with good treatment results. | Jie Zhou Yong Zhou Hulin Ma Zhiyun Li Jiaojing He Die Zhu Xiaodong Qu | 2015 | Oncology and Translational Medicine2015，1，6： | 0 |
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