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2篇 您的检索式:作者名="Jiaying Mo"
    题名 作者 年代 出处 被引量
1Developmental origins of adult diseases显示文摘The occurrence and mechanisms of developmental adult diseases have gradually attracted attention in recent years.Exposure of gametes and embryos to adverse environments,especially during plastic development,can alter the expression of certain tissue-specific genes,leading to increased susceptibility to certain diseases in adulthood,such as diabetes,cardiovascular disease,neuropsychiatric,and reproductive system diseases,etc.The occurrence of chronic disease in adulthood is partly due to genetic factors,and the remaining risk is partly due to environmental-dependent epigenetic information alteration,including DNA methylation,histone modifications,and noncoding RNAs.Changes in this epigenetic information potentially damage our health,which has also been supported by numerous epidemiological and animal studies in recent years.Environmental factors functionally affect embryo development through epimutation,transmitting diseases to offspring and even later generations.This review mainly elaborated on the concept of developmental origins of adult diseases,and revealed the epigenetic mechanisms underlying these events,discussed the theoretical basis for the prevention and treatment of related diseases.Jiaying Mo Xuanqi Liu Yutong Huang Renke He Yu Zhang Hefeng Huang 2022Medical Review2022,2,5:0
2Stretchable magnesium-air battery based on dual ions conducting hydrogel for intelligent biomedical applications显示文摘Flexible and bio-integrated electronics have attracted great attention due to their enormous contributions to personalized medical devices.Power sources,serving as one of the most important components,have been suffering from many problems,including deficient biocompatibility,poor stretchability,and unstable electrical outputs under deformed conditions,which limits the practical applications in flexible and bio-integrated electronics.Here,we reported a fully stretchable magnesium(Mg)–air battery based on dual-ions-conducting hydrogels(SDICH).The high-performance battery enables long-term operation with lighting 120 lighting emitting diodes(LEDs)for over 5 h.Benefiting from the advanced materials and mechanical designs,the battery exhibits stability electrical outputs under stretching,which allows to operate ordinarily under various mechanical deformations without performance decay.Furthermore,the great biocompatibility of the battery offers great opportunity for biomedical applications,which is demonstrated by a self-adaption wound dressing system.The in vitro and in vivo results prove that the self-adaption wound dressing can effectively prevent wound inflammation and promote wound healing.By exploiting thermal feedback mechanics,the system can adjust antibiotic release rate and dosage spontaneously according to the real-time wound conditions.The proposed fully stretchable Mg-air battery and self-adaption wound dressing display great potential in skin-integrated electronics and personalized medicine.Xingcan Huang Yiming Liu Wooyoung Park Zhao Zhao Jiyu Li Chee Kent Lim Tsz Hung Wong Chun Ki Yiu Yuyu Gao Jingkun Zhou HuLi Ling Zhao Jian Li Binbin Zhang Ya Huang Rui Shi Dengfeng Li Jiaying Mo Jinpei Wang Chao Zhang Yuhang Li Zuankai Wang Xinge Yu 2023InfoMat2023,5,3:0
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