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| 1 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 2 | Nonlinear formulation for flexible multibody system with large deformation显示文摘在这篇论文,非线性的建模为灵活多,有大变丑的身体系统被调查。绝对节的坐标被采用描述排水量,并且灵活身体的变化运动方程根据几何非线性的理论, shear 紧张和横向的正常紧张在被考虑被导出。由分开内部并且边界节的坐标,运动方程一灵活多,身体系统被装配。如此的明确的表达的优点是限制方程和向前递归的方程变得线性因为绝对节的坐标被使用。与一个球形的关节连接到地面的一只空间双摆钟被模仿与大变丑调查灵活横梁的动态表演。最后,结果的经常的全部的精力验证现在的明确的表达。 | Jinyang Liu Jiazhen Hong | 2007 | Acta Mechanica Sinica2007，23，1： | 11 |
| 3 | An exact nonlinear hybrid-coordinate formulation for flexible multibody systems显示文摘以前的低顺序的近似非线性的明确的表达成功了捕获使硬的条款,但是由于高顺序的变丑条款的疏忽与大变丑在机械系统的模拟失败了。在这篇论文,新混合坐标的明确的表达被建议,它对合适灵活多有大变丑的身体系统。根据准确种类排水量关系,运动为的方程灵活多,身体系统被使用虚拟工作导出原则。一个矩阵分离方法被提出改进计算的效率。有绝对节的并列明确的表达(ANCF ) 获得的那些的现在的结果的同意验证建议明确的表达的正确性。而且,现在的结果与线性模型和低顺序的近似非线性的模型的使用获得显示出建议模型的适用性的那些相比。 | Jinyang Liu Jiazhen Hong LinCui | 2007 | Acta Mechanica Sinica2007，23，6： | 10 |
| 4 | Effects of Primary Annealing Condition on Recrystallization Texture in a Grain Oriented Silicon Steel显示文摘The recrystallization texture in grain oriented silicon steel sheets, which were annealed at different primary annealing temperatures with and without an electric field, was investigated. An automated electron backscattered diffraction (EBSD) technique was used to analyze the recrystallization texture. It was found that recovery and application of electric field in primary annealing lead to an increase of {001} component and a decrease of {111} component after annealing at 900℃. The development of recrystallization texture can be explained in terms of the effects of electric field and primary annealing temperature on recovery. | Yubui SHA Fang ZHANG Song LI Xaoyu GAO Jiazhen XU Liang ZUO School of Materials and Metallurgy,Northeastern University,Shenyang 110004,China | 2004 | Journal of Materials Science & Technology2004，20，3： | 9 |
| 5 | Biosynthesis and combinatorial biosynthesis of antifungal nucleoside antibiotics显示文摘There is an urgent need for new antifungal agents to treat or combat fungal infection in humans and plants.Antifungal nucleoside antibiotics are an important family of natural products with distinctive structural features.Understanding their biosynthetic machinery is of great importance for the improvement of antibiotics titers.More importantly,it is a requisite for combinatorial biosynthesis to create hybrid nucleoside antibiotics.We herein focus on findings on the natural and designed biosynthesis of this important family of nucleoside antibiotics. | Guoqing Niu Jiazhen Zheng Huarong Tan | 2017 | Science China(Life Sciences)2017，60，9： | 8 |
| 6 | Important role of a LAL regulator Sta R in the staurosporine biosynthesis and high-production of Streptomyces fradiae CGMCC 4.576显示文摘Staurosporine, belonging to indolocarbazole compounds, is regarded as an excellent lead compound for synthesizing antitumor agents as a potent inhibitor against various protein kinases. In this study, two separate clusters(cluster A and cluster B),corresponding to biosyntheses of K-252 c(staurosporine aglycone) and sugar moiety, were identified in Streptomyces fradiae CGMCC 4.576 and heterologously expressed in Streptomyces coelicolor M1146 separately or together. Sta R, a cluster-situated LAL family regulator, activates staurosporine biosynthesis by binding to the promoter regions of sta O-sta C and sta G-sta N. The conserved sequences GGGGG and GCGCG were found through gradually truncating promoters of sta O and sta G, and further determined by mutational experiments. Overexpression of sta R with the supplementation of 0.01 g L^–1 Fe SO4 increased staurosporine production to 5.2-fold compared with that of the parental strain Streptomyces fradiae CGMCC 4.576 in GYM medium. Our results provided an approach for improvement of staurosporine production mediated by a positive regulator and established the basis for dissecting the regulatory mechanisms of other indolocarbazole compounds with clinical application value. | Hanye Guan Yue Li Jiazhen Zheng Ning Liu Jihui Zhang Huarong Tan | 2019 | Science China(Life Sciences)2019，62，12： | 6 |
| 7 | Paleoproterozoic Multistage Metamorphic Ages Registered in the Precambrian Basement Rocks at the Southeastern Margin of the North China Craton and Their Geological Implications显示文摘Objective The Precambrian basement rocks in the Bengbu and neighboring areas,located at the southeastern margin of the North China Craton,occur as granulite terrains and xenoliths in the Mesozoic dioritic porphyry.They provide an excellent natural laboratory to study the formation and evolution of the Precambrian lower crust in the region. | LIU Yican ZHANG Pingang WANG Chengcheng NIE Jiazhen | 2016 | Acta Geologica Sinica(English Edition)2016，90，6： | 6 |
| 8 | Ecological and environmental explanation of microbiotic crusts on sand dune scales in the Gurbantonggut Desert, Xinjiang显示文摘Results obtained from the field investigation and the analysis in laboratory show that many species of microbiotic crusts of lichens, mosses and algae develop extensively in the Gurbantonggut Desert, Xinjiang. The formation, species and distribution are closely related to the environmental conditions at the different positions of sand dunes. The animalcule crusts develop mainly on the mobile or semi-mobile sand surface of dune tops, the alga crusts develop mainly at the upper to middle parts of dune slopes, the lichen crusts develop at middle and lower parts of dune slopes, and the moss crusts are mainly distributed at the lower part of dune slopes and the interdune lowlands. The species, thickness and developing degree of microbiotic crusts increase from the upper part to the middle and lower parts of dune slopes and the interdune lowlands, and an obvious contrast between the microbiotic crusts and the different species of plant communities forms. The development and differentiation of microbiotic crusts at the different positions of dunes are the ecological appearance and the natural selection of synthetic adaptability of the different microbiotic crust species to the local environmental conditions, and are closely related to the ecological conditions, such as the physiochemical properties of soils and stability of topsoil texture. | CHEN Yaning LI Weihong ZHOU Zhibing LIU Jiazhen | 2005 | Progress in Natural Science:Materials International2005，15，12： | 5 |
| 9 | Biodegradable metals for bone defect repair:A systematic review and meta-analysis based on animal studies显示文摘Biodegradable metals are promising candidates for bone defect repair.With an evidence-based approach,this study investigated and analyzed the performance and degradation properties of biodegradable metals in animal models for bone defect repair to explore their potential clinical translation.Animal studies on bone defect repair with biodegradable metals in comparison with other traditional biomaterials were reviewed.Data was carefully collected after identification of population,intervention,comparison,outcome,and study design(PICOS),and following the inclusion criteria of biodegradable metals in animal studies.30 publications on pure Mg,Mg alloys,pure Zn and Zn alloys were finally included after extraction from a collected database of 2543 publications.A qualitative systematic review and a quantitative meta-analysis were performed.Given the heterogeneity in animal model,anatomical site and critical size defect(CSD),biodegradable metals exhibited mixed effects on bone defect repair and degradation in animal studies in comparison with traditional non-degradable metals,biodegradable polymers,bioceramics,and autogenous bone grafts.The results indicated that there were limitations in the experimental design of the included studies,and quality of the evidence presented by the studies was very low.To enhance clinical translation of biodegradable metals,evidence-based research with data validity is needed.Future studies should adopt standardized experimental protocols in investigating the effects of biodegradable metals on bone defect repair with animal models. | Jiazhen Zhang Yanbiao Jiang Zhizhong Shang Bing Zhao Mingyue Jiao Wenbo Liu Maobo Cheng Bao Zhai Yajuan Guo Bin Liu Xinli Shi Bin Ma | 2021 | Bioactive Materials2021，6，11： | 5 |
| 10 | Influence of Ethanolamine on Corrosion of Alloy 690 in Simulated Secondary Water显示文摘Effect of ethanolamine(ETA) on Alloy 690 in simulated pressurized water reactor(PWR) secondary cooling water was studied by electrochemical impedance spectroscopy(EIS), potentiodynamic polarization, atomic force microscopy(AFM), Fourier transform infrared spectroscopy-attenuated total reflectance(FTIR-ATR), X-ray photoelectron spectrometer(XPS) and time of flight secondary ion mass spectrometry(To F-SIMS). The results show that moderate addition of ETA can enhance the corrosion resistance of Alloy 690 in high-temperature pressurized water and the optimum additive value is 2 mg/L. The addition of ETA contributes to the formation of oxide rather than hydroxide in the film on the surface of Alloy 690. The corrosion resistance of Alloy 690 at 320 °C with the addition of ETA is better than that at280 °C. | Jiazhen Wang Jianqiu Wang | 2015 | Journal of Materials Science & Technology2015，31，10： | 4 |
| 11 | Diversity Analysis of Chlorophyll, Flavonoid, Anthocyanin, and Nitrogen Balance Index of Tea Based on Dualex显示文摘The chemical compositions of tea(Camellia sinensis)are affected by numerous factors,such as cultivar,climate,leaf position,and cultivation pattern.However,under the same conditions,the chemical compositions are mainly determined by varieties.Therefore,we investigated the genetic diversity of chemical compositions of tea tree resources in China to screen excellent germplasm resources.Three chemical compositions index(including chlorophyll index,flavonoid index,and anthocyanin index)and the nitrogen balance index of tea leaves were measured in 102 tea germplasms planted in Chinese Tea Plants Improved Variety Germplasm Resources Nursery(CTPIVGRN)by Dualex on April 152019.Results showed that the chlorophyll,flavonoid,and anthocyanin contents and the nitrogen balance index significantly differed between the 102 tea germplasms.The genetic diversity index values were 2.005,2.246,1.599,and 1.838,and the average genetic diversity was 1.922.The 102 tea germplasms can be divided into four categories by cluster analysis under the genetic distance threshold of 11.These results suggest that the genetic diversity of tea germplasm resources in China is rich.This study’s results can serve as a basis for the diversified development and utilization of tea plant. | Yifu Liu Jiazhen Wang Yao Xiao Xiongwen Shi Yixia Zeng | 2021 | Phyton-International Journal of Experimental Botany2021，90，5： | 4 |
| 12 | Low-frequency Stimulation at the Subiculum is Anti-convulsant and Anti-drug-resistant in a Mouse Model of Lamotrigine-resistant Temporal Lobe Epilepsy显示文摘Dear Editor,Epilepsy is a common neurological disease.About 30%of epileptic patients develop resistance to antiepileptic drugs(AEDs),and are considered to have refractory or drugresistant epilepsy[1].Based on the time course over which drug-resistance develops,refractory epilepsy can be further divided into an early-onset type(drug-resistance more likely innate and correlated with gene mutations)and a delayed-onset type(drug-resistance emerges after a period of medication)[2]. | Yeping Ruan Cenglin Xu Jile Lan Jiazhen Nao Shuo Zhang Fei Fan Yi Wang Zhong Chen | 2020 | Neuroscience Bulletin2020，36，6： | 4 |
| 13 | A novel dense descriptor based on structure tensor voting for multi-modal image matching显示文摘Automatic and robust matching of multi-modal images can be challenging owing to the nonlinear intensity differences caused by radiometric variations among these images.To address this problem,a novel dense feature descriptor and improved similarity measure are proposed for enhancing the matching performance.The proposed descriptor is built on a voting scheme of structure tensor that can effectively capture the geometric structural properties of images.It is not only illumination and contrast invariant but also robust against the degradation caused by significant noise.Further,the similarity measure is improved to adapt to the reversal of orientation caused by the intensity inversion between multi-modal images.The proposed dense feature descriptor and improved similarity measure enable the development of a robust and practical templatematching algorithm for multi-modal images.We verify the proposed algorithm with a broad range of multi-modal images including optical,infrared,Synthetic Aperture Radar(SAR),digital surface model,and map data.The experimental results confirm its superiority to the state-of-the-art methods. | Jiazhen LU Maoqing HU Jing DONG Songlai HAN Ang SU | 2020 | Chinese Journal of Aeronautics2020，33，9： | 3 |
| 14 | Synthesis and Fungicidal Activity of (E)-5-[1-(2-Oxo- 1 -oxaspiro[4,5]dec/non-3-en-3-yl)ethylidene]-2- aminoimidazolin-4-one Derivatives显示文摘 | Bo Tang Aiying Guan Yu Zhao Jiazhen Jiang Mingan Wang Ligang Zhou | 2017 | Chinese Journal of Chemistry2017，35，7： | 3 |
| 15 | Self-alignment of full skewed RSINS: observability analysis and full-observable Kalman filter显示文摘Traditional orthogonal strapdown inertial navigation system(SINS) cannot achieve satisfactory selfalignment accuracy in the stationary base: taking more than 5 minutes and all the inertial sensors biases cannot get full observability except the upaxis accelerometer. However, the full skewed redundant SINS(RSINS) can not only enhance the reliability of the system, but also improve the accuracy of the system, such as the initial alignment. Firstly, the observability of the system state includes attitude errors and all the inertial sensors biases are analyzed with the global perspective method: any three gyroscopes and three accelerometers can be assembled into an independent subordinate SINS(subSINS); the system state can be uniquely confirmed by the coupling connections of all the subSINSs; the attitude errors and random constant biases of all the inertial sensors are observable. However, the random noises of the inertial sensors are not taken into account in the above analyzing process. Secondly, the fullobservable Kalman filter which can be applied to the actual RSINS containing random noises is established; the system state includes the position, velocity, attitude errors of all the subSINSs and the random constant biases of the redundant inertial sensors. At last, the initial selfalignment process of a typical fourredundancy full skewed RSINS is simulated: the horizontal attitudes(pitch, roll) errors and yaw error can be exactly evaluated within 80 s and 100 s respectively, while the random constant biases of gyroscopes and accelerometers can be precisely evaluated within 120 s. For the full skewed RSINS, the selfalignment accuracy is greatly improved, meanwhile the selfalignment time is widely shortened. | Lailiang Song Chunxi Zhang Jiazhen Lu | 2014 | Journal of Systems Engineering and Electronics2014，25，1： | 3 |
| 16 | Review of recent progresses on flexible oxide semiconductor thin film transistors based on atomic layer deposition processes显示文摘The current article is a review of recent progress and major trends in the field of flexible oxide thin film transistors(TFTs), fabricating with atomic layer deposition(ALD) processes. The ALD process offers accurate controlling of film thickness and composition as well as ability of achieving excellent uniformity over large areas at relatively low temperatures. First, an introduction is provided on what is the definition of ALD, the difference among other vacuum deposition techniques, and the brief key factors of ALD on flexible devices. Second, considering functional layers in flexible oxide TFT, the ALD process on polymer substrates may improve device performances such as mobility and stability, adopting as buffer layers over the polymer substrate, gate insulators, and active layers. Third, this review consists of the evaluation methods of flexible oxide TFTs under various mechanical stress conditions. The bending radius and repetition cycles are mostly considering for conventional flexible devices. It summarizes how the device has been degraded/changed under various stress types(directions). The last part of this review suggests a potential of each ALD film, including the releasing stress, the optimization of TFT structure, and the enhancement of device performance. Thus, the functional ALD layers in flexible oxide TFTs offer great possibilities regarding anti-mechanical stress films, along with flexible display and information storage application fields. | Jiazhen Sheng Ki-Lim Han TaeHyun Hong Wan-Ho Choi Jin-Seong Park | 2018 | Journal of Semiconductors2018，39，1： | 3 |
| 17 | The impact of government incentives and penalties on willingness to recycle plastic waste: An evolutionary game theory perspective显示文摘Because governments have introduced policies involving incentives and penalties to promote the recycling of plastic waste,it is important to understand the impact of such incentives and penalties on the willingness of stakeholders to participate.In this study,government is included as a player,alongside waste collectors and recyclers,in a tripartite evolutionary game model of plastic waste recycling.The study explores the evolutionary equilibrium and performs a simulation analysis to elucidate the effect of government incentives and penalties on the willingness of other players to participate in recycling.Three conclusions are drawn from this research.First,an increase in incentives or in penalties increases the probability that collectors and recyclers will participate in the recycling process.Second,policy support incentives encourage collectors and recyclers to participate in plastic waste recycling earlier than subsidy incentives do.Finally,recyclers are more sensitive than collectors to government-imposed penalties. | Zhen Wang Jiazhen Huo Yongrui Duan | 2020 | Frontiers of Environmental Science & Engineering2020，14，2： | 2 |
| 18 | Design and performance evaluation of additively manufactured composite lattice structures of commercially pure Ti(CP-Ti)显示文摘Ti alloys with lattice structures are garnering more and more attention in the field of bone repair or regeneration due to their superior structural,mechanical,and biological properties.In this study,six types of composite lattice structures with different strut radius that consist of simple cubic(structure A),body-centered cubic(structure B),and edge-centered cubic(structure C)unit cells are designed.The designed structures are firstly simulated and analysed by the finite element(FE)method.Commercially pure Ti(CP-Ti)lattice structures with optimized unit cells and strut radius are then fabricated by selective laser melting(SLM),and the dimensions,microtopography,and mechanical properties are characterised.The results show that among the six types of composite lattice structures,combined BA,CA,and CB structures exhibit smaller maximum von-Mises stress,indicating that these structures have higher strength.Based on the fitting curves of stress/specific surface area versus strut radius,the optimized strut radius of BA,CA,and CB structures is 0.28,0.23,and 0.30 mm respectively.Their corresponding compressive yield strength and compressive modulus are 42.28,30.11,and 176.96 MPa,and 4.13,2.16,and 7.84 GPa,respectively.The CP-Ti with CB unit structure presents a similar strength and compressive modulus to the cortical bone,which makes it a potential candidate for subchondral bone restorations. | Wei Xu Aihua Yu Xin Lu Maryam Tamaddon Mengdi Wang Jiazhen Zhang Jianliang Zhang Xuanhui Qu Chaozong Liu Bo Su | 2021 | Bioactive Materials2021，6，5： | 2 |
| 19 | Density estimated physicochemical properties of alanine-based ionic liquid [C_7mim][Ala] and its application in selective transesterification of soybean oil显示文摘Amino acid ionic liquid (AAIL) based on alanine, 1-n-heptyl-3-methylimidazolium alanine ([C7mim][Ala]), has been prepared and characterized. Since the IL can form strong hydrogen bonds with water, trace amount of water is a problematic impurity in the IL. Using the standard addition method (SAM), the densities were measured in the temperature range from 293.15 to 343.15±0.05 K. On the basis of the experimental data of density, the surface tension , molar volume, and the molecular volume Vm, molar enthalpy of vaporization lgHm0, and the thermal expansion coefficients , for [C7mim][Ala] were estimated using semi-empirical methods. Also the interstice model has been verified with good accordance. Then the [C7mim][Ala] was taken as catalyst in the transesterification reaction with fatty acid, where soybean oil was used as raw material and methanol as reactant. The amount of catalyst, alcohol consumption, reaction time, temperature and other factors of the reaction were investigated. Using GC determination, the conversions were calculated by the internal standard method. The main ingredients of the products were identified by GC-MS as palm methyl ester and linoleic acid methyl ester only, which showed high selectivity in palmitic acid and linoleic acid. | FANG DaWei LI Meng GE RiLe ZANG ShuLiang YANG JiaZhen GAO YanAn | 2012 | Science China Chemistry2012，55，8： | 2 |
| 20 | Enhancing Photocatalytic Performance of NH 2-UIO66 by Defective Structural Engineering显示文摘NH_(2)-UIO66(NU)is a promising photocatalyst for the reduction of Cr(VI)to low-toxic Cr(III)driven by visible light under ambient conditions.However,the main limitation in this process is the ineffi cient ligand to metal charge transfer(LMCT)of photo-excited electrons,which is caused by inherent energy gap(ΔE_(LMCT)).This study synthesized the defective NU(NUXH,where X is the molar equivalent of the modulator)with reducedΔE_(LMCT)through linkers removal via acid treatment.The electronic structure of NUX-H was systematically investigated,and the results indicated that the structural defects in NUX-H strongly altered the environment of the Zr atoms.Furthermore,they substantially lowered the energy of the unoccupied d orbitals(LUMO),which was benefi cial to effi cient LMCT,resulting in an improved photocatalytic activity of NUX-H toward high-concentration(100 mg/L)Cr(VI)reduction.Compared to NU with defect-free structure,the reducing rate of Cr(VI)was increased by 47 times.This work introduced an alternative strategy in terms of designing effi cient photocatalysts for reducing Cr(VI)under ambient conditions. | Zhenmin Xu Jiazhen Cao Xiang Chen Liyi Shi Zhenfeng Bian | 2021 | Transactions of Tianjin University2021，27，2： | 2 |
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