|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs显示文摘Objective:To evaluate in ritro antimicrobial activities of selected 58 ethno-medicinal plant extracts with a view to assess their therapeutic potential.Methods:A total of 58 traditional Chinese medicinal plants were carefully selected based on the literature review and their traditional use.The antimicrobial activities of ethanol extracts of these medicinal plants were tested against fungi(Aspergillus funigaius),yeast(Candida albicans),gram-negative(Acirelobacter haumannii and Pseudornnruis aeruginosa)and gram-positive bacteria(Staphglococcus aureus).The activities were tested at three different concentrations of 1.00,0.10 and 0.01 mg/mL.The data was analysed using Gene data Screener program.Results:The measured antimicrobial activities indicated that out of the 58 plant extracts,15 extracts showed anti-fungal activity and 23 extracts exhibited anti-bacterial activity.Eight plant extracts have exhibited both anti-bacterial and anti-fungal activities.For instance,Eucommia ulmoides,Pohgonum cuspidcrtum,Poria cocas and Uncaria rhineophylla showed activity against both bacterial and fungal strains,indicating their broad spectrum of activity.Conclusions:The results revealed that the ethanol extracts of 30 plants out of the selected 58 possess significant antimicrobial activities.It is interesting to note that the findings from the current study are consistent with the traditional use.A clear correlation has also been found between the antimicrobial activity and the flavonoid content of the plant extracts which is in agreement with the literature.Hence.the results presented here can be used to guide the selection of potential plant species for the isolation and structure elucidation of novel antimicrobial compounds in order to establish the structure-activity relationship.This in turn is expected to lead the way to the discovery of novel antimicrobial agents for therapeutic use. | Lin Zhang Anjaneya S.Ravipati Sundar R Koyyalamudi Sang Chul Jeong Narsimha Reddy John Bartlett Paul T.Smith Mercedes de la Cruz Maria Cndida Monteiro ngeles Melguizo Ester Jimnez Francisca Vicente | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，9： | 23 |
| 2 | Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation显示文摘航线发炎是许多呼吸障碍的特点,例如气喘和膀胱的纤维变性。在发炎触发的航线基因表示的变化在这些疾病的致病起一个关键作用。基因连接研究建议 ESE-2 和 ESE-3,编码上皮特定的 Ets-domain-containing 抄写因素,是候选人气喘危险性基因。我们这里报导 et 家庭抄写因素 ESE-1 的另一个成员的表示,以及 ESE-3,起来在支气管的上皮的房间线由煽动性的 cytokines interleukin-1beta (IL-1beta ) 和肿瘤坏死 factor-alpha (TNF-alpha ) 调整了。有 IL-1beta 和 TNF-alpha 的这些房间的处理为 ESE-1 和 ESE-3 导致了信使 rna 表示的戏剧的增加。我们证明导致的表示被抄写因素 NF-kappaB 的激活调停。我们描绘了 ESE-1 和 ESE-3 倡导者并且识别了为导致 cytokine 的表达式被要求的 NF-kappaB 有约束力的序列。另外,我们也表明那 ESE-1 在上面调整 ESE-3 表示, down 由 cytokines 调整它的自己的正式就职。最后,我们在 Elf3 显示出那(对人的 ESE-1 相应) 猛烈老鼠,煽动性的 cytokine interleukin-6 (IL-6 ) 的表示是调整的 down。我们的调查结果建议 ESE-1 和 ESE-3 在航线发炎起一个重要作用。 | Jing Wu Rongqi Duan Huibi Cao Deborah Field Catherine M Newnham David R Koehler Noe Zamel Melanie A Pritchard Paul Hertzog Martin Post A Keith Tanswell Jim Hu | 2008 | Cell Research2008，18，6： | 6 |
| 3 | A systematic review of the clinical effectiveness of pioglitazone in the treatment of type 2 diabetes mellitus显示文摘 | Jim Chilcott Paul Tappenden Myfanwy Lloyd Jones Jeremy P. Wight | 2001 | Clinical Therapeutics2001，，11： | 2 |
| 4 | National-scale Assessment of Current and Future Flood Risk in England and Wales显示文摘 | Jim W. Hall Paul B. Sayers Richard J. Dawson | | Natural Hazards (-)0，，： | 2 |
| 5 | A randomised controlled trial of intervention site radiotherapy in malignant pleural mesothelioma显示文摘 | Noelle O Rourke Jose Curto Garcia Jim Paul | 2007 | Radiotherapy and Oncology2007，84，： | 1 |
| 6 | 体重调整固定剂量普通肝素与低分子肝素治疗急性静脉血栓栓塞的比较显示文摘背景:普通肝素用于治疗急性静脉血栓栓塞时,通常在监测血凝下静脉输注给药,患者需要住院治疗。然而,体重调整后皮下注射固定剂量普通肝素可能既适用于住院也适用于门诊静脉血栓栓塞患者的治疗。
目的:确定皮下注射体重调整固定剂量普通肝素治疗静脉血栓栓塞是否与低分子肝素同样安全有效。设计、地点及患者:随机、开标、裁定者盲法、非劣效试验。708例急性静脉血栓栓塞患者来自加拿大和新西兰6所大学附属临床中心,年龄≥18岁。试验于1998年9月至2004年2月进行。在随机分组的患者中,11例从疗效分析中排除,8例从安全性分析中排除。
干预:普通肝素皮下注射初始剂量为333U/kg,以后给予固定剂量250U/kg,每12小时1次(n=345)。低分子肝素(依诺肝素或达肝素)按100IU/kg剂量皮下注射,每12小时1次(n=352)。两种治疗均可院外进行,配合华法林治疗3个月。
主要观测指标:随机分组后3个月内复发性静脉血栓栓塞事件及10天内严重出血情况。结果:普通肝素组有13例患者(3.8%)发生静脉血栓栓塞复发,而低分子肝素组有12例患者复发(3.4%;绝对差值,0.4%;95%可信区间,-2.6%~3.3%)。开始治疗后10天内普通肝素组有4例患者(1.1%)发生严重出血,而低分子肝素组有5例(1.4%;绝对差值,-0.3%;95%可信区间,-2.3%~1.7%)。院外治疗患者在普通肝素组占72%,低分子肝素组占68%。
结论:对于急性静脉血栓栓塞患者而言,皮下注射固定剂量普通肝素与低分子肝素一样安全有效,适于门诊治疗。 | Clive Kearon Jeffrey S. Ginsberg Jim A. Julian James Douketis Susan Solymoss Paul Ockelford Sharon Jackson Alexander G. Turpie Betsy MacKinnon Jack Hirsh Michael Gent 王春玲(译) 孙艺红(译) 胡大一(校) | 2007 | 美国医学会杂志(中文版)2007，26，5： | 1 |
| 7 | Quantifying Damage, Saturation and Anisotropy in Cracked Rocks by Inverting Elastic Wave Velocities显示文摘 | Alexandre Schubnel Philip M. Benson Ben D. Thompson Jim F. Hazzard R. Paul Young | | 0，2006，： | 1 |
| 8 | Heavy load vibration isolation system for airborne payloads 显示文摘 | Steve Hadden Torey Davis Paul Buchele Jim Boyd Tim Hintz | 2001 | SPIE2001，4332，： | 1 |
| 9 | Sand Binder Systems Part VI-The Shell Process显示文摘 | Paul Carey K Larry Roubitehek Jim Green | 1995 | Foundry M&T1995，123，08： | 1 |
| 10 | The Open Provenance Model core specification (v1.1)显示文摘 | Luc Moreau Ben Clifford Juliana Freire Joe Futrelle Yolanda Gil Paul Groth Natalia Kwasnikowska Simon Miles Paolo Missier Jim Myers Beth Plale Yogesh Simmhan Eric Stephan Jan Van den Bussche | 2010 | Future Generation Computer Systems2010，，： | 1 |
| 11 | A Review of Performance Measurement: Towards Performance Management显示文摘 | Paul Folan Jim Browne | 2005 | Computers in Industry2005，56，7： | 1 |
| 12 | A new classification of Cyperaceae (Poales) supported by phylogenomic data显示文摘Cyperaceae(sedges)are the third largest monocot family and are of considerable economic and ecological importance.Sedges represent an ideal model family to study evolutionary biology due to their species richness,global distribution,large discrepancies in lineage diversity,broad range of ecological preferences,and adaptations including multiple origins of C4 photosynthesis and holocentric chromosomes.Goetghebeur′s seminal work on Cyperaceae published in 1998 provided the most recent complete classification at tribal and generic level,based on a morphological study of Cyperaceae inflorescence,spikelet,flower,and embryo characters,plus anatomical and other information.Since then,several family-level molecular phylogenetic studies using Sanger sequence data have been published.Here,more than 20 years after the last comprehensive classification of the family,we present the first family-wide phylogenomic study of Cyperaceae based on targeted sequencing using the Angiosperms353 probe kit sampling 311 accessions.In addition,62 accessions available from GenBank were mined for overlapping reads and included in the phylogenomic analyses.Informed by this backbone phylogeny,a new classification for the family at the tribal,subtribal,and generic levels is proposed.The majority of previously recognized suprageneric groups are supported,and for the first time,we establish support for tribe Cryptangieae as a clade including the genus Koyamaea.We provide a taxonomic treatment including identification keys and diagnoses for the 2 subfamilies,24 tribes,and 10 subtribes,and basic information on the 95 genera.The classification includes five new subtribes in tribe Schoeneae:Anthelepidinae,Caustiinae,Gymnoschoeninae,Lepidospermatinae,and Oreobolinae. | Isabel Larridon Alexandre R.Zuntini Étienne Léveillé-Bourret Russell L.Barrett Julian R.Starr AMuthama Muasya Tamara Villaverde Kenneth Bauters Grace E.Brewer Jeremy J.Bruhl Suzana M.Costa Tammy L.Elliott Niroshini Epitawalage Marcial Escudero Isabel Fairlie Paul Goetghebeur Andrew LHipp Pedro Jiménez-Mejías Izai ABSabino Kikuchi Modesto Luceño JoséIgnacio Márquez-Corro Santiago Martín-Bravo Olivier Maurin Lisa Pokorny Eric HRoalson Ilias Semmouri David A.Simpson Daniel Spalink WWayt Thomas Karen L.Wilson Martin Xanthos Félix Forest William J.Baker | 2021 | Journal of Systematics and Evolution2021，59，4： | 1 |
| 13 | Depression and anxiety in long-term cancer survivors compared with spouses and healthy controls: a systematic review and meta-analysis显示文摘 | Alex J Mitchell David W Ferguson John Gill Jim Paul Paul Symonds | 2013 | Lancet Oncology2013，，8： | 1 |
| 14 | The serv- ice system is the basic abstraction of service science显示文摘 | PAUL P STEPHEN L V NATHAN C JIM S | 2009 | In formation Systems and e-Business Management2009，7，4： | 1 |
| 15 | Bank Capital St-ructure,Regulatory Capital,and Securities Innovations显示文摘 | George Benston Paul Ir-vine Jim Rosenfeld Joseph F.Sinkey JR | | 0，，35： | 1 |
| 16 | The MILS architecture for high-assurance embedded systems显示文摘 | Jim Alves-Foss W.Scott Harrison Paul Oman Carol Taylor | | 0，，04： | 1 |
| 17 | A review of performance measurement :Towardsperformancemanagement 显示文摘 | PAUL FOLAN JIM BROWNE | 2005 | Computers in Industry2005，56，： | 1 |
| 18 | Predicting Adverse Outcomes inElective Coronary Artery Bypass Graft Surgery using Pre-operativeTroponin I Levels 显示文摘 | Edward B Paul C Jim D | 2014 | Heart Lung and Circulation2014，08，14： | 1 |
| 19 | Distributed query processing on the grid 显示文摘 | Smith Jim Watson Paul | 2003 | The International Journal of High Performance Computing Applications2003，17，4： | 1 |
| 20 | A Review of Performance Measurement: Towards Performance Management 显示文摘 | Paul Folan Jim Browne | 2005 | Computers in Industry2005，56，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员