| 1 | The Digital Belt and Road program in support of regional sustainability显示文摘The Belt and Road initiative has a significant focus on infrastructure,trade,and economic development across a vast region,and it also provides significant opportunities for sustainable development.The combined pressure of climate variability,intensified use of resources,and the fragility of ecosystems make it very challenging,however,to achieve future sustainability.To develop the path in a sustainable way,it is important to have a comprehensive understanding of these issues across nations and evaluate them in a scientific and well-informed approach.In this context,the Digital Belt and Road(DBAR)program was initiated as an international venture to share expertise,knowledge,technologies,and data to demonstrate the role of Earth observation science and technology and big Earth data applications to support large-scale development.In this paper,we identify pressing challenges,present the research priorities and foci of the DBAR program,and propose solutions where big Earth data can make significant contributions.This paper calls for further joint actions and collaboration to build a digital silk road in support of sustainable development at national,regional and global levels. | Huadong Guo Jie Liu Yubao Qiu Massimo Menenti Fang Chen Paul F.Uhlir Li Zhang John van Genderen Dong Liang Ishwaran Natarajan Lanwei Zhu Jiuliang Liu | 2018 | International Journal of Digital Earth2018,11,7: | 1 |
| 2 | Sex differences in systemic lupus erythematosus(SLE):an inception cohort of the Chinese SLE Treatment and Research Group(CSTAR)registry XVII显示文摘Background:The onset and clinical presentation of systemic lupus erythematosus(SLE)are sex-related.Few studies have investigated the distinctions in clinical characteristics and treatment preferences in male and female SLE patients in the initial cohort.This study aimed to improve the understanding of Chinese SLE patients by characterizing the different sexes of SLE patients in the inception cohort.Methods:Based on the initial patient cohort established by the Chinese SLE Treatment and Research Group,a total of 8713 patients(795 men and 7918 women)with newly diagnosed SLE were enrolled between April 2009 and March 2021.Of these,2900 patients(347 men and 2553 women)were eligible for lupus nephritis(LN).A cross-sectional analysis of the baseline demographic characteristics,clinical manifestations,laboratory parameters,organ damage,initial treatment regimens,and renal pathology classification was performed according to sex.Results:In the SLE group,as compared to female patients,male patients had a later age of onset(male vs.female:37.0±15.8 years vs.35.1±13.7 years,P=0.006)and a higher SLE International Collaborative Clinic/American College of Rheumatology damage index score(male vs.female:0.47±1.13 vs.0.34±0.81,P=0.015),LN(male vs.female:43.6%vs.32.2%,P<0.001),fever(male vs.female:18.0%vs.14.6%,P=0.010),thrombocytopenia(male vs.female:21.4%vs.18.5%,P=0.050),serositis(male vs.female:14.7%vs.11.7%,P=0.013),renal damage(male vs.female:11.1%vs.7.4%,P<0.001),and treatment with cyclophosphamide(CYC)(P<0.001).The frequency of leukopenia(male vs.female:20.5%vs.25.4%,P=0.002)and arthritis(male vs.female:22.0%vs.29.9%,P<0.001)was less in male patients with SLE.In LN,no differences were observed in disease duration,SLE Disease Activity Index score,renal biopsy pathological typing,or 24-h urine protein quantification among the sexes.In comparisons with female patients with LN,male patients had later onset ages(P=0.026),high serum creatinine(P<0.001),higher end-stage renal failure rates(P=0.002),musculoskeletal damage(P=0.023),cardiovascular impairment(P=0.009),and CYC use(P=0.001);while leukopenia(P=0.017),arthritis(P=0.014),and mycophenolate usage(P=0.013)rates were lower.Conclusions:Male SLE patients had more severe organ damage and a higher LN incidence compared with female SLE patients;therefore,they may require more aggressive initial treatment compared to female patients. | Yinli Gui Wei Bai Jian Xu Xinwang Duan Feng Zhan Chen Zhao Zhenyu Jiang Zhijun Li Lijun Wu Shengyun Liu Min Yang Wei Wei Ziqian Wang Jiuliang Zhao Qian Wang Xiaomei Leng Xinping Tian Mengtao Li Yan Zhao Xiaofeng Zeng CSTAR co-authors | 2022 | Chinese Medical Journal2022,135,18: | 0 |
| 3 | A Food Traceability Framework Based on Permissioned Blockchain显示文摘In recent years,food safety problems have become increasingly serious.The traditional supply chain traceability solution faces some serious problems,such as centralization,data tampering,and high communication costs.To solve these problems,this paper proposes a food traceability framework based on permissioned blockchain.The proposed framework is decentralized,and the supply chain data of the framework cannot be tampered with.The framework divides supply chain entities into five organizations,and each organization deploys its own chaincode onto the blockchain.The chaincode specifies the query permission of each organization,which can effectively protect the user’s sensitive information.The PBFT consensus algorithm adopted by the framework improves the performance of processing transactions.The transactional throughput experiment shows that the proposed framework can achieve a high number of transactions per second.Query efficiency experiment demonstrates that the framework has lower query latency and good user experience. | Jiuliang Liu Xingming Sun Ke Song | 2020 | Journal of Cyber Security2020,2,2: | 0 |