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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Polyamines reduces lipid peroxidation induced by different pro-oxidant agents显示文摘 | Nádia Aléssio Velloso Bellé Gerusa Duarte Dalmolin Graciela Fonini Maribel Antonello Rubin Jo?o Batista Teixeira Rocha | 2004 | Brain Research2004，，2： | 3 |
| 3 | Lateral neck dissection for well-differentiated thyroid carcinoma: a system- atic review显示文摘 | Madcnci AL Caragacianu D Boeckmann JO | 2014 | Laryngoscope2014，124，7： | 1 |
| 4 | Genetic risk factors in infertile men with severe oligozoospermia and azoosperrnia显示文摘 | Dohle GR Halley D J Van Hemel JO el al | 2002 | Hum Reprod2002，17，1： | 1 |
| 5 | Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence显示文摘 | Olsen AL Smith VJ Bergstrom JO | 1997 | Obstet Gynecol1997，8，： | 1 |
| 6 | Epidemiology of surgi- cally managed pelvic organ prolapse and urinary inconti- nence 显示文摘 | Olsen AL Smith VJ Bergstrom JO | 1997 | Obstet Gynecol1997，89，4： | 1 |
| 7 | Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence显示文摘 | Olsen AL Smith VJ Bergstrom JO | 1997 | Obstet Gynecol1997，89，4： | 1 |
| 8 | A multiobjective modeling approach to locating incinerators显示文摘 | Luís Al?ada-Almeida Jo?o Coutinho-Rodrigues John Current | 2008 | Socio-Economic Planning Sciences2008，，2： | 1 |
| 9 | Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence显示文摘 | Olsen AL Smith VJ Bergstrom JO | 1997 | Obstet Gynecol1997，89，4： | 1 |
| 10 | Global soft decision employing support vector machine for speech enhancement 显示文摘 | Chang J H Jo Q H Kim D K at al | 2008 | IEEESignal Process Lett2008，16，1： | 1 |
| 11 | Usefulness of a dopamine transporter PET ligand bela-CFT in assessing disability in Parkinson ' s disease显示文摘 | Rinne JO Ruotlinen H Bergnmn J el al | 1999 | J Neurol Neurosurg Psychiatry1999，67，： | 1 |
| 12 | Epidemaiology of surgically managed pelvic organ prolapse and urinary incontinence显示文摘 | Olsen AL Smith VJ Bergstrom JO | 1997 | Obstet Gynecol1997，89，4： | 1 |
| 13 | Coronary Circulatory Dysfunction in Insulin Resistance, Im- paired Glucose Tolerance and Type 2 Diabetes Mellitus显示文摘 | Prior JO Quinones MJ Hernandez-Pampaloni M Facta AD et al | 2005 | Circu- lation2005，111，： | 1 |
| 14 | Cardiac amyloidosis ,ithout increased leI 'entricular wall thickn,ss 显示文摘 | Lee GY Kim K Choi JO el al | 2014 | Mayo Clin Proc2014，89，： | 1 |
| 15 | Epidemidogy of surgically managed pelvic organ prolapse and urinary incontinence显示文摘 | Olesn AL Smith VJ Bergstrom JO | 1997 | Obstet Gynecol1997，89，4： | 1 |
| 16 | Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence显示文摘 | Olsen AL Smith VJ Bergstrom JO | 1997 | Obstet Gynecol1997，89，： | 1 |
| 17 | Chemical and ant|microbial treatments change the viscoelastic properties of bacterial bilffilms显示文摘 | Jo les WL Sutton MP McKittrick L el al | 2011 | Biofouling2011，27，2： | 1 |
| 18 | Salivary receptors for the praline - rich protein - binding and lectin - like adhesins of oral actinomyces and streptococci 显示文摘 | Ruhl S Sandberg AL Cisar JO | 2004 | J Dent Res2004，83，6： | 1 |
| 19 | Round Robin Analysis of Pressurized Thermal Shock for Reactor Pressure Vessel显示文摘 | Myung Jo Jhung Seok Hun Kim Jin Ho lee at al | 2003 | Nuclear Engineering and Design2003，226，： | 1 |
| 20 | Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence显示文摘 | Olsen AL Smith V J Bergstrom JO | 1997 | Obstet Gynecol1997，89，4： | 1 |
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