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| 1 | Utilization of Swertia chirayita Plant Extracts for Management of Diabetes and Associated Disorders: Present Status, Future Prospects and Limitations显示文摘Diabetes mellitus is referred as common metabolic abnormalities characterized as hyperglycemia,mainly caused due to insufficient production of insulin at cellular level or/and defects in insulin action.Such an endocrine disorder is responsible for serious health problems and its worldwide prevalence is rapidly increasing.Common management of diabetes by oral administration of drugs without creating any side effects is still considered a challenging task and increasing cost of con-ventional medicine in developing countries is another matter of concern.To address these issues,traditional preparations of herbal plant extracts in the form of medicines already gained immense attention.Swertia chirayita is one among such plants which is known for its hypoglycemic potential.Numerous chemical constituents with promising pharmacological properties have been identified from such plant extracts but still,such compounds have not been well characterized,specifically against human application.Hence,more research efforts are necessitated to understand exact mechanism of such compounds and to develop overall safety of such plant formulations.Present review clearly represents antidiabetic properties of Swertia chirayita extract,strategies to be taken to strengthen its safety application on humans and biotechnological interventions that ensure conservation of such endangered species to promote its future application in modern medicine. | Pinaki Dey Joginder Singh Jagadish Kumar Suluvoy Kevin Joseph Dilip Jayato Nayak | 2020 | Natural Products and Bioprospecting2020，10，6： | 2 |
| 2 | Simple design for a reflectometer显示文摘 | Om Prakash Joginder Singh etc | 1991 | Optical Engineering1991，30，4： | 1 |
| 3 | 工农业废料及其固态发酵利用综述显示文摘农业残余物富含生物活性物质。这些残余物可用作替代资源,用于生产沼气、生物燃料、蘑菇和印尼豆豉等产品,并作为各类研究及各行业的原料。工农业废料的资源化利用有助于降低生产成本和环境污染负荷。通过固态发酵(SSF),工农业废料可用于制造生物燃料、酶、维生素、抗氧化剂、动物饲料、抗生素及其他化学物品。通过固态发酵生产此类有价值产品时,会涉及多种微生物的使用。文章介绍并探讨了固态发酵及其对附加值产品生产的影响。 | Pardeep Kumar Sadh Surekha Duhan Joginder Singh Duhan 徐娟(译) | 2019 | 中国沼气2019，37，6： | 1 |
| 4 | Conservation Strategy for African Medicinal Species: In Vitro Biotechnological Approach显示文摘The use of medicinal plants for different therapeutic values is well documented in African continent.African diverse biodiversity hotspots provide a wide range of endemic species,which ensures a potential medicinal value.The feasible conservation approach and sustainable harvesting for the medicinal species remains a huge challenge.However,conservation approach through different biotechnological tools such as micropropagation,somatic embryogenesis,synthetic seed production,hairy root culture,molecular markers based study and cryopreservation of endemic African medicinal species is much crucial.In this review,an attempt has been made to provide different in vitro biotechnological approaches for the conservation of African medicinal species.The present review will be helpful in further technology development and deciding the priorities at decision-making levels for in vitro conservation and sustainable use of African medicinal species. | Priyanka Jha Swati Chahal Devendra Kumar Pandey Joginder Singh Ram Prasad Vijay Kumar | 2020 | Phyton-International Journal of Experimental Botany2020，89，4： | 1 |
| 5 | Radiometric measurement on rotating object 显示文摘 | S P Varma Joginder Singh | 1990 | Infrared Phys1990，30，1： | 1 |
| 6 | Stress Ameliorative Effects of Indole Acetic Acid on Hordeum vulgare L. Seedlings Subjected to Zinc Toxicity显示文摘The heavy metals present in the environment accumulate in the plants and affect their productivity and yield.By entering the food chain,metals cause several serious health problems in human beings as well as in other organisms.Indole acetic acid(IAA)is known to act as a signaling molecule between symbiotic association of metal accumulating plants and plant growth promoting rhizobacteria(PGPR).Present study demonstrated a protective role of IAA against surplus Zinc(Zn)-induced toxicity to Hordeum vulgare seedlings.Elevated Zn concentrations suppressed the plant growth,caused a reduction in leaf relative water contents(RWC)and elevated free proline and non-protein thiols(NPT)accumulation.Zinc treatment also led to enhanced lipid peroxidation(MDA contents)as well as the activity of ascorbate peroxidase(APX),showing the involvement of antioxidative defense mechanism to reduce Zn induced toxicity.IAA oxidase activity was also observed to increase due to Zn treatment.IAA pretreatment of H.vulgare caryopsis could partly revert the Zn-induced toxicity in seedlings. | Monika Sood Shanti S.Sharma Joginder Singh Ram Prasad Dhriti Kapoor | 2020 | Phyton-International Journal of Experimental Botany2020，89，1： | 0 |
| 7 | Therapeutic Applications of Naringenin, a Flavanone Enriched in Citrus Fruits, for Disorders beyond Diabetes显示文摘In recent years,there has been an increase in epidemiological studies to highlight the health benefits of plant secondary metabolites.Flavonoids(polyphenolic plant secondary metabolites)are recently emerging as an important source for the discovery of new drugs increasing their pharmaceuticals,nutraceutical and medicinal applications.Naringenin is a flavanone,enriched in citrus fruits,tomatoes,bergamot,etc.which has been evaluated extensively for managing diabetes.However,in addition to this,naringenin had been ascribed to various important biological activities like antioxidant,antiviral,anticancer,anti-inflammatory,antiestrogenic,etc.This article aims at highlighting the therapeutic value of naringenin in managing disorders other than diabetes and its role in regulating gene expression by altering chromatin structure as histone deacetylase inhibitor.The understanding of these phenomena will increase the overall knowledge of the various health-promoting effects of citrus fruits. | Jaswinder Kaur Manish Vyas Joginder Singh Ram Prasad Jeena Gupta | 2020 | Phyton-International Journal of Experimental Botany2020，89，4： | 0 |
| 8 | Phytochemistry and ethnomedicinal qualities of metabolites from Phyllanthus emblica L.:A review显示文摘Phyllanthus emblica or Indian gooseberry is an integrated part of Ayurvedic and Traditional Chinese Medicines.For several decades,the well-known ancient herb has been extensively utilized in traditional medicine to cure diseases like fever,diabetes,constipation,jaundice,ulcers,biliousness,anemia,anorexia,and dyspepsia.In the traditional system,Indian gooseberry has various ethnomedicinal applications.In the Ayurvedic system,different methods of administration(anupan)have shown different ethnomedicinal properties of Indian gooseberry.Seventy well-known chemical components in Indian gooseberry have been identified through phytochemical evaluation,among which the flavonoids and phenols are most prominent.From the toxicity perspective,it is considered a safe herb in India,and is taken as a food supplement in European countries.The wide-spectrum pharmacological activities of the crude extracts and isolates of Indian gooseberry are attributed to the predominance of phenols and flavonoids.Thus,it is important to study the exact mechanism of the activity of the phytochemicals in Indian gooseberry,especially in anti-cancer activities.Extract of Indian gooseberry enhances proliferation in several cancer cells in vitro,including stem cells like ovarian cancer(OC)cells,and also has been observed to possess anti-proliferative characteristics in vivo.This review intends to explore the therapeutic potential of Indian gooseberry based on scientific reports and attempts to find the gaps for future research. | VIJAY KUMAR PRAVEEN C.RAMAMURTHY SIMRANJEET SINGH DALJEET SINGH DHANJAL PARUL PARIHAR DEEPIKA BHATIA RAM PRASAD JOGINDER SINGH | 2023 | BIOCELL2023，47，5： | 0 |
| 9 | Convective stability analysis of a micropolar fluid layer by variational method显示文摘This paper studies Rayleigh-B'enard convection of micropolar fluid layer heated from below with realistic boundary conditions.A specific approach for stability analysis of a convective problem based on variational principle is applied to characterize the Rayleigh number for quite general nature of bounding surfaces.The analysis consists of replacing the set of field equations by a variational principle and the expressions for Rayleigh number are then obtained by using trial function satisfying the essential boundary conditions.Further,the values of the Rayleigh number for particular cases of large and small values of the microrotation coefficient have been obtained.The effects of wave number and micropolar parameter on the Rayleigh numbers for onset of stationary instability for each possible combination of the bounding surfaces are discussed and illustrated graphically.The present analysis establishes that the nature of bounding surfaces combination and microrotation have significant effect on the onset of convection. | Joginder S.Dhiman Praveen K.Sharma Gurdeep Singh | 2011 | Theoretical & Applied Mechanics Letters2011，1，4： | 0 |
| 10 | Folate-producing rhizobacteria of Hippophae rhamnoides L.from Indian trans-Himalaya low atmospheric zone显示文摘Hippophae rhamnoides L.is a plant of immense ethnopharmacological importance and is a known source for various valuable biochemicals and nutraceuticals.The production of folate,a vitamin involved in several vital functions,in this plant is rather poorly understood.Herein,we investigate the hypothesis that rhizobial bacteria serve the plant in this essential vitamin’s biosynthesis.Bacterial strains of Bacillus,Azorhizobium,Frankia,Paenibacillus,Brevibacillus and Pseudomonas,were isolated from the rhizosphere of the plant.HPLC and LCMS were used to trace the production of intra and extra-cellular folate by representative rhizospheric bacterial strains in vitro.From the seventeen functionally characterized bacterial strains of the plant’s rhizosphere,thirteen produced significant amounts of folate.Azorhizobium BR5401 produced the maximum amount of folic acid(424μg/mL),and Bacillus GY779 was the only strain capable of producing both intracellular and extra-cellular folic acid.The Open Reading Frame coding for dihydroneopterin aldolase,an enzyme involved in folate biosynthesis,was found in one of the representative isolates.Our experimental findings help us to suggest that the folate synthesized by rhizobial bacteria is transported to the plant,highlighting a significant benefit of coexistence. | POOJA BHADRECHA MADHU BALA VIKAS KAUSHIK NASEEM A.GAUR SIMRANJEET SINGH JOGINDER SINGH MANOJ KUMAR | 2021 | BIOCELL2021，45，2： | 0 |
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