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您的检索式：作者名="John M.Moore"
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| 1 | Epstein-Barr病毒特异性T细胞对重组痘苗病毒表达LMP和EBNA2的靶细胞的识别显示文摘本文用EB病毒转化自体淋巴细胞所建立的类淋巴母细胞系(LCL),以及用EB病毒潜伏感染膜蛋白(LMP)基因和核蛋白-2(EBNA2)基因与痘苗病毒重组的重组病毒(Vac-LMP和Vac-EBNA2)感染的自身纤维母细胞,同时作为刺激细胞和靶细胞,以^(51)Cr释放法检测5例血清中EB病毒VCA—IgA抗体阳性者及1例阴性健康者外周血单个核细胞(PBMC)的特异性T细胞杀伤效应。结果表明,用自身LCL激活的EB病毒特异性T细胞杀伤效应高峰出现在第14~28天;参与杀伤性细胞免疫反应的T细胞亚群主要是T3、T8阳性的细胞毒性T细胞,其对靶细胞的识别及杀伤受HLA-I的限制。用重组牛痘病毒感染的纤维母细胞作靶细胞或刺激细胞,有1例供者可接受LMP,另1例可接受EBNA2的刺激,并对相应的靶细胞产生特异性T细胞杀伤反应,表明EB病毒-LMP和EBNA2可能既是EB病毒特异性T细胞的刺激抗原,又是其识别的靶抗原。 | 陈小毅 A.Ghosh M.Moore John Arrand | 1991 | 病毒学报1991，7，2： | 2 |
| 2 | 加拿大2个不整合面型金矿床的地球化学和成因显示文摘Addington和Ore Chimney是元古代含金石英一碳酸盐脉矿床,它们产在较低级的角闪岩相变质岩中,在一较大的区域性不整合面上或其附近。 Ore Chimney矿床是一典型的不透明的矿物组合——方铅矿-闪锌矿-黄铁矿-黄铜矿-磁黄铁矿-富银黝铜矿-钛铁矿。脉系赋存在一厚4m的黑云母片岩中,此黑云母片岩周围为变玄武熔岩流。变火山岩之上不整合地覆盖着厚10m的变泥质石榴石-黑云母片岩(Ore Chimney建造)和一粗的硅质碎屑岩(Flinton组).Ore Chimney矿床出现在不整合面之下30m处。 Addington矿床具有典型的不透明的毒砂-黄铁矿-黄铜矿-磁黄铁矿-钛铁矿的矿物群。这个矿床赋存在Ore Chimney建造内,并位于沿走向距Ore Chimney矿山8km处。毒砂地温测量和闪锌矿地压测量获得温度和压力,估计范围分别为420—530℃和0.35—0.59GPa,与估计的顶峰变质条件是一致的。地球化学、结构和构造证据表明,脉建造和矿化是在主变质和变形幕期间发生的,金是经由变质流体而沉积的.矿化作用与围岩的弱碳酸盐化有关。金和贱金属可以从热液和/或风化作用生成早期浓度中重新活动。 | Luc Harnois John M.Moore 严平兴 | 1992 | 国外铀金地质1992，，3： | 0 |
| 3 | Cannabinoids function in defense against chewing herbivores in Cannabis sativa L.显示文摘In the decades since the first cannabinoids were identified by scientists,research has focused almost exclusively on the function and capacity of cannabinoids asmedicines and intoxicants for humans and other vertebrates.Very little is knownabout the adaptive value of cannabinoid production,though several hypotheses have been proposed including protection from ultraviolet radiation,pathogens,and herbivores.To test the prediction that genotypeswith greater concentrations of cannabinoidswill have reduced herbivory,a segregating F2 population of Cannabis sativa was leveraged to conduct lab-and field-based bioassays investigating the function of cannabinoids in mediating interactions with chewing herbivores.In the field,foliar cannabinoid concentration was inversely correlated with chewing herbivore damage.On detached leaves,Trichoplusia ni larvae consumed less leaf area and grew less when feeding on leaves with greater concentrations of cannabinoids.Scanning electron and light microscopy were used to characterize variation in glandular trichome morphology.Cannabinoid-free genotypes had trichomes that appeared collapsed.To isolate cannabinoids from confounding factors,artificial insect diet was amended with cannabinoids in a range of physiologically relevant concentrations.Larvae grew less and had lower rates of survival as cannabinoid concentration increased.These results support the hypothesis that cannabinoids function in defense against chewing herbivores. | George M.Stack Stephen I.Snyder Jacob A.Toth Michael A.Quade Jamie L.Crawford John K.McKay John Nicholas Jackowetz Ping Wang Glenn Philippe Julie L.Hansen Virginia M.Moore Jocelyn K.C.Rose Lawrence B.Smart | 2023 | Horticulture Research2023，10，11： | 0 |
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