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| 1 | 可及性照顾(一)显示文摘 | John W.Saultz MD 梁万年 李航 | 2002 | 中国全科医学2002，5，5： | 8 |
| 2 | Microarray,SAGE and their applications to cardiovascular diseases显示文摘The wealth of DNA data generated by the human genome project coupling with recently invented high-throughput gene expression profiling techniques has dramatically sped up the process for biomedical researchers on elucidating the role of genes in human diseases. One powerful method to reveal insight into gene functions is the systematic analysis of gene expression. Two popular high-throughput gene expression technologies, microarray and Serial Analysis of Gene Expression (SAGE) are capable of producing large amounts of gene expression data with the potential of providing novel insights into fundamental disease processes, especially complex syndromes such as cardiovascular disease, whose etiologies are due to multiple genetic factors and their interplay with the environment. Microarray and SAGE have already been used to examine gene expression patterns of cell-culture, animal and human tissues models of cardiovascular diseases. In this review, we will first give a brief introduction of microarray and SAGE technologies and point out their limitations. We will then discuss the major discoveries and the new biological insightsthat have emerged from their applications to cardiovascular diseases. Finally we will touch upon potential challenges and future developments in this area. | SHUI QING YE, TERA LAVOIE, DAVID C USHER, LI Q. ZHANG1 Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD 21224, USA2Department of Biological Science, University of Delaware, Newark, DE 19716, USA | 2002 | Cell Research2002，12，2： | 5 |
| 3 | 学科内团队康复显示文摘学科内团队和多学科团队是两个不同的概念。我国学术界过去多将其作为同一概念。国际物理医学与康复医学学会主席Melvin教授深入浅出地分析了这两个概念之间的差别 ,学科内团队发展的历史及其意义 ,同时深刻地分析了临床治疗技术的提高及医疗政策改变所引起的学科内团队模式的新挑战、新发展趋势和新策略 。 | John L.Melvin MD MMSc 励建安 | 2002 | 中国康复医学杂志2002，17，2： | 5 |
| 4 | Gastrointestinal Stromal Tumors: Current Diagnosis, Biologic Behavior, and Management显示文摘 | Ihor Pidhorecky MD Richard T. Cheney MD William G. Kraybill MD John F. Gibbs MD | 2000 | Annals of Surgical Oncology2000，，9： | 5 |
| 5 | Prevalence of fatty liver in Japanese children and relationship to obesity显示文摘 | Kunihiko Tominaga MD Dr Ph John H. Kurata PhD Dr. Yang K. Chen MD Edward Fujimoto DHSc MPH Shouhei Miyagawa Ichiro Abe MSA Yoshimasa Kusano BS | | Digestive Diseases and Sciences0，，： | 5 |
| 6 | 早产儿视网膜病变早期治疗(ETROP)过程中发生视网膜脱离眼的预后显示文摘研究对象:在早产儿视网膜病变早期治疗(ETROP)研究中因早产儿视网膜病变(ROP)而发生视网膜脱离眼的结构以及功能改变。
研究方法:加入ETROP研究中的新生儿患有双眼高危阈前ROP,随即对其一眼进行早期治疗,另一眼进行传统治疗。只有单眼患病的早产儿。随机对高危阈前ROP眼进行早期治疗或传统治疗。当视网膜脱离被发现时。研究者会继续观察患者病变或对其行视网膜玻璃体手术(如巩膜加压术以肜或者玻璃体切除术)。在矫正9月龄时,对患者视网膜状况进行评估并使用条栅视敏度(grating acuity)对患儿视力进行检测。
研究结果:401例高危阈前ROP患者加入了ETROP研究。63例患者(89只眼)发生了视网膜脱离。对其中56例患者(78只眼)进行了随访。21例患者(38%)的视网膜脱离发生于双眼。其中30只眼分级为4A,14只眼为4B,16只眼为5级。余下的18只视网膜脱离眼未进行分级。对11例患者(12只眼)监控病情变化,52例患者(66只眼)行玻璃体视网膜手术。行玻璃体切除伴或不伴有巩膜加压术的56只眼中有17只(30%)在患者9月龄时保持或达到了黄斑复位;仅行巩膜加压术的10只眼中,6只(60%)达到;未行手术的12只眼中,2只(17%)达到。78只眼中有13只(17%)达到了较好的视力水平(I〉1.85cycles/degree)。达到正常视力水平(≥3.70cycles/degree)的6只眼的视网膜脱离分级均为4A(其分别为6只未行手术眼中的1眼,6只行巩膜加压术眼中的3眼。18只行玻璃体切除术眼中的2眼)。对11只视网膜脱离达5级的患眼行玻璃体视网膜手术。
治疗结果为6只眼无光感,3只眼仅有光感,2只眼只能看清低视力表。结论:在ETROP的研究中,ROP导致视网膜脱离的治疗结果普遍较差。因视网膜脱离行玻璃体视网膜手术的48只眼中,有16只眼黄斑未发生脱离。手术修复4A级视网膜脱离的24只眼中,有5只(21%)在术后达到了正常视力水平。对视网膜脱离5级眼行玻璃体视网膜手术可以使其达到结构复位,但功能恢复不佳。 | Michael X. Repka Betty Tung William V. Good Michael Shapiro Antonio Capone Jr John D. Baker Charles C. Barr Dale L. Phelps W. A. J. van HewvenMD John D. Baker,MD Charles C. Barr,MD Dale L. Phelps,MD IV. A. J. van Heuven 张弛(译) | 2006 | 美国医学会眼科杂志(中文版)2006，18，3： | 4 |
| 7 | 以整体观念发展人体功能和康复研究显示文摘WHO发布的《国际功能、残疾与健康分类》,为全面理解将损伤的生物医学观点与残疾的社会模式整合在一起的人体功能与康复研究奠定了基础。它提出了在提高研究能力方面面临的一系列新旧挑战。本文将从三个方面概述应对这些挑战的方法:建立深入到不同科学领域的人体功能与康复研究的组织;发展合适的学术培训项目;建立大学研究中心和合作网络。 | Gerold Stucki, MD, MS Jan Dietrich Reinhardt, PhD Gunnar Grimby, MD, PhD John Melvin, MD, MMSc 李露(译) 卫小梅(译) 郭铁成(校) | 2008 | 中华物理医学与康复杂志2008，30，1： | 4 |
| 8 | Treatment of hepatocellular carcinoma显示文摘 | Jonathan M. Schwartz MD John M. Ham MD | 2003 | Current Treatment Options in Gastroenterology2003，，6： | 3 |
| 9 | 综合性照顾(一)显示文摘 | John W.Saultz MD 梁万年 李航 | 2002 | 中国全科医学2002，5，9： | 3 |
| 10 | Pancreatic Resection of Isolated Metastases from Nonpancreatic Primary Cancers显示文摘 | Sushanth Reddy MD Barish H. Edil MD John L. Cameron MD Timothy M. Pawlik MD MPH Joseph M. Herman MD Marta M. Gilson PhD Kurtis A. Campbell MD Richard D. Schulick MD Nita Ahuja MD Christopher L. Wolfgang MD PhD | 2008 | Annals of Surgical Oncology2008，，11： | 2 |
| 11 | Natural history of alcoholic hepatitis显示文摘 | Mark W. Lischner MD James F. Alexander MD John T. Galambos MD | 1971 | The American Journal of Digestive Diseases1971，，6： | 2 |
| 12 | Animal models of fulminant hepatic failure显示文摘 | John Terblanche ChM FCS(SA) FRCS(Eng) FRCPS(Glasg) FACS(Hon) Rosemary Hickman ChM MD | 1991 | Digestive Diseases and Sciences1991，，6： | 2 |
| 13 | 综合性照顾(二)显示文摘 | John W.Saultz MD 梁万年 李航 | 2002 | 中国全科医学2002，5，10： | 2 |
| 14 | Adjuvant Chemoradiation for Pancreatic Adenocarcinoma: The Johns Hopkins Hospital—Mayo Clinic Collaborative Study显示文摘 | Charles C. Hsu MD PhD Joseph M. Herman MD MSc Michele M. Corsini MD Jordan M. Winter MD Matthew D. Callister MD Michael G. Haddock MD John L. Cameron MD Timothy M. Pawlik MD MPH Richard D. Schulick MD Christopher L. Wolfgang MD PhD Daniel A. Laheru MD | 2010 | Annals of Surgical Oncology2010，，4： | 2 |
| 15 | Acute pancreatitis and organ failure: Pathophysiology, natural history, and management strategies显示文摘 | Michael G. T. Raraty FRCS PhD Saxon Connor FRACS David N. Criddle PhD Robert Sutton DPhil FRCS John P. Neoptolemos MA MD FRCS | 2004 | Current Gastroenterology Reports2004，，2： | 2 |
| 16 | Gastrointestinal Stromal Tumors: Current Diagnosis, Biologic Behavior, and Management显示文摘 | Ihor Pidhorecky MD Richard T. Cheney MD William G. Kraybill MD John F. Gibbs MD | 2000 | Annals of Surgical Oncology2000，，9： | 2 |
| 17 | Status of the Specialty of Physical and Rehabilitation Medicine显示文摘The objectives of this paper are to help specialists in Physical and Rehabilitation Medicine plan their careers, influence the future of the PRM specialty and advocate effectively for those with limitations of functioning. The experiences of the authors are the sources of its observations and suggestions. The senior author has had extensive national and international experience in the specialty as a clinician, teacher, researcher, manager, leader and advocate. The junior author adds the insights of one who only recently has become immersed in PRM. The following are suggestions and observations the authors believe could contribute to the future success of individual PRM specialists and the PRM specialty. ①Review and reinforce the significant accomplishments of PRM over the last 70 years. It has significantly expanded the focus of health care to include the importance of functioning. ②Identify the specialty′s current strengths, weaknesses, threats and opportunities. As a clinical specialty, it has expanded nationally and internationally, yet its research contributions remain limited. The absence of an evidence base for much of its activity risks reduced support from payers, yet the population needing its services continues to expand. ③Develop strategies to increase the ability of PRM specialists and PRM to improve the lives of people with or likely to have limitations of functioning. These strategies could include sharing best practices, supporting effectiveness research and developing expert consensus guidelines. The need for physicians who are experts in the strategies of improving the lives of those with complex problems of functioning will continue to expand. This need will assure the continuation of the specialty of PRM as long as it improves the abilities of its members to help those with problems of functioning, and it advocates for those whom its members serve. | John L . Melvin, MD MMSc John W. Norbury, MD | 2010 | 中国康复医学杂志2010，25，9： | 2 |
| 18 | The Use of Simvastatin for the Prevention of Gallstones in the Lithogenic Prairie Dog Model显示文摘 | Kurt G Davis MD Thomas M Wertin MD John P Schriver MD FACS | 2003 | Obesity Surgery2003，，6： | 2 |
| 19 | The year in Cardiothoracic and Vascular Anesthesia:Selected Highlights From 2009显示文摘 | Harish Ramakrishna, MD, FASE Jens Fassl, MD Ashish Sinha, MD Prakash Patel, MD Hynek Riha, MD, DEAA, FCCP Michael Andritsos, MD Insung Chung,MD John G.T. Augoustides, MD, FASE, FAHA | 2010 | 麻醉与监护论坛2010，17，3： | 2 |
| 20 | Comparison of Central and Extended Left Pancreatectomy for Lesions of the Pancreatic Neck显示文摘 | Lee M. Ocuin MD Juan M. Sarmiento MD Charles A. Staley MD John R. Galloway MD Colin D. Johnson MD William C. Wood MD David A. Kooby MD | 2008 | Annals of Surgical Oncology2008，，8： | 2 |
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