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6篇 您的检索式:作者名="Johnathan E"
    题名 作者 年代 出处 被引量
1Holladay, Heather Brown,et al Metal Chlorides in lonic liquid Solvents Convert Sugars to 5-Hydroxymethylfurfural 显示文摘Haibo Zhao Johnathan E 2007Science2007,316,5831:1
2Metal chlorides in ionic liquid solvents convert sugars to 5- hydroxymethylfurfural 显示文摘Haibo Zhao Johnathan E Hollyaday eather Brown Z 2007Science2007,316,:1
3Metal chlorides in ionic liquid solvent covert sugars to 5-hydroxymethyfurafural显示文摘ZHAO Haibo JOHNATHAN E H HEATHER B 2007Science2007,316,5831:1
4Metal chlorides in ionic liquid solvents convert sugars to 5-hydroxymethylfurfural显示文摘Zhao Haibo Holladay Johnathan E Brown Heather 0,,5831:1
5New frontiers in oilseed biotechnology: meeting the global demand for vegetable oils for food, feed, biofuel, and industrial applications显示文摘Chaofu Lu Johnathan A Napier Thomas E Clemente Edgar B Cahoon 2010Current Opinion in Biotechnology2010,,2:1
6Functional magnetic resonance imaging in an animal model of pancreatic cancer显示文摘AIM: To test the hypotheses that diffusion weighed (DW)and transcatheter intraarterial perfusion (TRIP)magnetic resonance imaging (MRI) can each be used to assess regional differences in tumor function in an animal pancreatic cancer model.METHODS: VX2 tumors were implanted in pancreata of 6 rabbits. MRI and digital subtraction angiography (DSA) were performed 3 wk following implantation. With a 2-French catheter secured in the rabbit's gastroduodenal artery, each rabbit was transferred to an adjacent 1.5T MRI scanner. DWand TRIP-MRI were performed to determine if necrotic tumor core could be differentiated from viable tumor periphery. For each, we compared mean differences between tumor core/ periphery using a 2-tailed paired t-test (α = 0.05). Imaging was correlated with histopathology. RESULTS: Tumors were successfully grown in all rabbits, confirmed by necropsy. On DW-MRI, mean apparent diffusion coeffi cient (ADC) value was higher in necrotic tumor core (2.1 ± 0.3 mm2/s) than in viable tumor periphery (1.4 ± 0.5 mm2/s) (P < 0.05). On TRIP-MRI, mean perfusion values was higher in tumor periphery (110 ± 47 relative units) than in tumor core (66 ± 31 relative units) (P < 0.001). CONCLUSION: Functional MRI can be used to differentiate necrotic from viable tumor cells in an animal pancreatic cancer model using ADC (DW-MRI) and perfusion (TRIP-MRI) values.Robert J Lewandowski Aaron C Eifler David J Bentrem Johnathan C Chung Gayle E Woloschak Robert Ryu Riad Salem Andrew C Larson Reed A Omary 2010World Journal of Gastroenterology2010,16,26:0
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