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| 1 | Hormonal protection in acute pancreatitis by ghrelin, leptin and melatonin显示文摘Acute pancreatitis is a nonbacterial disease of the pancreas.The severe form of this ailment is characterized by high mortality.Whether acute pancreatitis develops as the severe type or resolves depends on the intensity of the inflammatory process which is counteracted by the recruitment of innate defense mechanisms.It has been shown that the hormones ghrelin,leptin and melatonin are able to modulate the immune function of the organism and to protect the pancreas against inflammatory damage.Experimental studies have demonstrated that the application of these substances prior to the induction of acute pancreatitis significantly attenuated the intensity of the inflammation and reduced pancreatic tissue damage.The pancreatic protective mechanisms of the above hormones have been related to the mobilization of non-specific immune defense,to the inhibition of nuclear factor kappa B and modulation of cytokine production,to the stimulation of heat shock proteins and changes of apoptotic processes in the acinar cells,as well as to the activation of antioxidant system of the pancreatic tissue.The protective effect ofghrelin seems to be indirect and perhaps dependent on the release of growth hormone and insulin-like growth factor 1.Leptin and ghrelin,but not melatonin,employ sensory nerves in their beneficial action on acute pancreatitis.It is very likely that ghrelin,leptin and melatonin could be implicated in the natural protection of the pancreatic gland against inflammatory damage because the blood levels of these substances increase in the initial phase of pancreatic inflammation.The above hormones could be a part of the innate resistance system which might remove noxious factors and could suppress or attenuate the inflammatory process in the pancreas. | Jolanta Jaworek Stanis?aw Jan Konturek | 2014 | World Journal of Gastroenterology2014，20，45： | 10 |
| 2 | Mechanism of endothelial dysfunction in chronic kidney disease显示文摘 | Jolanta Malyszko | 2010 | Clinica Chimica Acta2010，，19： | 9 |
| 3 | Oxidative stress factors in Parkinson's disease显示文摘Parkinson's disease(PD) is the second most common cause of neurodegeneration.Over the last two decades, various hypotheses have been proposed to explain the etiology of PD.Among these is the oxidant-antioxidant theory, which asserts that local and systemic oxidative damage triggered by reactive oxygen species and other free radicals may promote dopaminergic neuron degeneration.Excessive reactive oxygen species formation, one of the underlying causes of pathology in the course of PD has been evidenced by various studies showing that oxidized macromolecules including lipids, proteins, and nucleic acids accumulate in brain tissues of PD patients.DNA oxidation may produce various lesions in the course of PD.Mutations incurred as a result of DNA oxidation may further enhance reactive oxygen species production in the brains of PD patients, exacerbating neuronal loss due to defects in the mitochondrial electron transport chain, antioxidant depletion, and exposure to toxic oxidized dopamine.The protein products of SNCA, PRKN, PINK1, DJ1, and LRRK2 genes are associated with disrupted oxidoreductive homeostasis in PD.SNCA is the first gene linked with familial PD and is currently known to be affected by six mutations correlated with the disorder: A53T, A30P, E46K, G51D, H50Q and A53E.PRKN encodes Parkin, an E3 ubiquitin ligase which mediates the proteasome degradation of redundant and disordered proteins such as glycosylated α-synuclein.Over 100 mutations have been found among the 12 exons of PRKN.PINK1, a mitochondrial kinase highly expressed in the brain, may undergo loss of function mutations which constitute approximately 1–8% of early onset PD cases.More than 50 PD-promoting mutations have been found in PINK1.Mutations in DJ-1, a neuroprotective protein, are a rare cause of early onset PD and constitute only 1% of cases.Around 20 mutations have been found in DJ1 among PD patients thus far.Mutations in the LRRK2 gene are the most common known cause of familial autosomal dominant PD and sporadic PD.Treatment of PD patients, especially in the advanced stages of the disease, is very difficult.The first step in managing progressive PD is to optimize dopaminergic therapy by increasing the doses of dopamine agonists and L-dopa.The next step is the introduction of advanced therapies, such as deep brain stimulation.Genetic factors may influence the response to L-dopa and deep brain stimulation therapy and the regulation of oxidative stress.Consequently, research into minimally invasive surgical interventions, as well as therapies that target the underlying etiology of PD is warranted. | Jolanta Dorszewska Marta Kowalska Michał Prendecki Thomas Piekut Joanna Kozłowska Wojciech Kozubski | 2021 | Neural Regeneration Research2021，16，7： | 7 |
| 4 | Disease-specific health-related quality of life and its determinants in liver cirrhosis patients in Lithuania显示文摘AIM: To evaluate disease-specific quality of life (QOL) in liver cirrhosis patients and to compare it with those of a healthy population. Also an important objective was to assess whether QOL in liver cirrhosis patients differs by age and gender, by type and severity of disease. METHODS: The case group of 131 liver cirrhosis patients was selected. The control group of 262 was enrolled from a healthy population according to the scheme of case-control study. Clinical, demographic, laboratory data were collected. QOL was measured with a specific chronic liver disease questionnaire (CLDQ), which was translated and validated in Lithuanian. QOL scores were compared between groups by age, gender, type and severity of disease. Cronbach’s alpha statistics calculation was used for evaluation of internal consistency reliability. Student’s t test or ANOVA were used for evaluation hypothesis about probability equation. RESULTS: QOL was significantly lower in liver cirrhosis patients than in healthy population (59.5 ± 18.3 vs 85.3 ± 12.3, P < 0.001). The significant QOL differences between case and control groups were observed in domains of worry and abdominal symptoms, the smaller differences-in emotional functions and systematic symptom domains. Significantly worse QOL was in observed patients with increased clinical severity of the disease measured by Child-Pugh class. Age, gender and etiology of disease had an insignificant effect on QOL in cirrhotic patients. CONCLUSION: QOL was significantly impaired in all CLDQ domains in liver cirrhosis patients. Increase in severity of disease was the major factor associated with poorer QOL. | Jolanta Sumskiene Linas Sumskas Dalius Petrauskas Limas Kupcinskas | 2006 | World Journal of Gastroenterology2006，12，48： | 6 |
| 5 | High frequency of the c.3207C>A (p.H1069Q) mutation in ATP7B gene of Lithuanian patients with hepatic presentation of Wilson's disease显示文摘AIM: To investigate the prevalence of the ATP7B gene mutation in patients with hepatic presentation of Wilson's disease (WD) in Lithuania. METHODS: Eleven unrelated Lithuanian families, including 13 WD patients were tested. Clinically WD diagnosis was established in accordance to the Leipzig scoring system. Genomic DNA was extracted fromwhole venous blood using a salt precipitation method. Firstly, the semi-nested polymerase chain reaction (PCR) technique was used to detect the c.3207C>A (p.H1069Q) mutation. Patients not homozygous for the c.3207C>A (p.H1069Q) mutation were further analyzed. The 21 exons of the WD gene were amplified in a thermal cycler (Biometra T3 Thermocycler, G?ttingen, Germany). Direct sequencing of the amplified PCR products was performed by cycle sequencing using fluorescent dye terminators in an automatic sequencer (Applied Biosystems, Darmstadt, Germany). RESULTS: Total of 13 WD patients (mean age 26.4 years; range 17-40; male/female 3/10) presented with hepatic disorders and 16 their first degree relatives (including 12 siblings) were studied. Some of WD patients, in addition to hepatic symptoms, have had extrahepatic disorders (hemolytic anemia 3; Fanconi syndrome 1; neurophsychiatric and behavioural disorder 2). Liver biopsy specimens were available in all of 13 WD patients (8 had cirrhosis; 1-chronic hepatitis; 3-acute liver failure, 1-liver steatosis). Twelve of 13 (92.3%) WD patients had the c.3207C>A (p.H1069Q) mutation, 6 of them in both chromosomes, 6 were presented as compound heterozygotes with additional c.3472-82delGGTTTAACCAT, c.3402delC, c.3121C>T (p.R1041W) or unknown mutations. For one patient with liver cirrhosis and psychiatric disorder (Leipzig score 6), no mutations were found. Out of 16 first degree WD relatives, 11 (68.7%) were heterozygous for the c.3207C>A (p.H1069Q) mutation. Two patients with fulminant WD died from acute liver failure and 11 are in full remission under penicillamine or zinc acetate treatment. Three women with WD successfully delivered healthy babies. CONCLUSION: The c.3207C>A (p.H1069Q) missense mutation is the most characteristic mutation for Lithuanian patients with WD. Even 92.3% of WD patients with hepatic presentation of the disease are homozygous or compound heterozygotes for the p.H1069Q mutation. | Laimutis Kucinskas Jolanta Jeroch Astra Vitkauskiene Raimundas Sakalauskas Vitalija Petrenkiene Vaidutis Kucinskas Rima Naginiene Hartmut Schmidt Limas Kupcinskas | 2008 | World Journal of Gastroenterology2008，14，38： | 5 |
| 6 | Semen analysis standardization: is there any problem in Polish laboratories?显示文摘学习的目的是决定对世界健康组织的波兰的实验室的依从的度() 建议,关于精液分析方法论。关于精液分析的方法请求信息的调查被散布到 55 个实验室的雇员。参予了外部 seminological 专题讨论会的回答者(31 %) 被称为证明回答者(CR ) ,留下(69 %)—非证明的回答者(NCR ) 。仅仅一个实验室(6 %) 在 CR,在 NCR 的组和没有遵循为方法和设备的指南使用了谁评估精液的体积,精子活动性,集中,活力和形态学。大多数问题具有体积测量(称方法被 17 % 报导;CR 和 10 %NCR ) 并且为精子形态学染色方法(Papanicolau 或 Diff-Quik 在 33 % 被发现;CR 和 23 %NCR ) 。三点或四点的 A 精子活动性分级被回答者的多数使用;然而, 17 %CR 和 37 %没 NCR 使用一个实验室柜台计算精子。尽管一个 haemocytometer 方法被 80 % 使用;在每个组的实验室,改进 Neubauer 房间仅仅由 42 % 被使用;CR 和 19 %NCR。在每个组, 24 %没实验室执行活力测试。程序的错误和二的可互换的利用或甚至三个方法在两个组被观察分析一个给定的参数。结果为方法的标准化显示需要并且连续,在波兰的实验室在精液分析训练统一。 | Renata Walczak-Jedrzejowska Katarzyna Marc hlewsks Elzbieta Oszukowska Eliza Filipiak Leszek Bergier Jolanta Slowikowska-Hilczer | 2013 | Asian Journal of Andrology2013，15，5： | 4 |
| 7 | Phagocytic and oxidative burst activity of neutrophils in the end stage of liver cirrhosis显示文摘AIM: To evaluate the phagocytic activity and neutrophil oxidative burst in liver cirrhosis.METHODS: In 45 patients with advanced postalcoholic liver cirrhosis (aged 45±14 years) and in 25 healthy volunteers (aged 38±5 years), the percentage of phagocytizing cells after in vitro incubation with E. coli (Phagotest Kit), phagocytic activity (mean intensity of fluorescence, MIF) and the percentage of neutrophil oxidative burst (Bursttest Kit), and the level of free oxygen radical production (MIF of Rodamine 123)were analyzed by flow cytometry. The levels of soluble sICAM-1, sVCAM-1, sP-selectin, sE-selectin, sL-selectin,and TNF-α were determined in blood serum.RESULTS: The percentage of E. coli phagocytizing neutrophils in liver cirrhosis patients was comparable to that in healthy subjects. MIF of neutrophil - ingested E. coli was higher in patients with liver cirrhosis. The oxidative burst in E. coli phagocytizing neutrophils generated less amount of active oxygen compounds in liver cirrhosis patients (MIF of R123:24.7±7.1 and 29.7±6.6 in healthy,P<0.01). Phorbol myristate acetate (PMA) - stimulated neutrophilsproduced less reactive oxidants in liver cirrhosis patients than in healthy subjects (MIF of R123: 42.7±14.6 vs 50.2±13.3, P<0.01). A negative correlation was observed between oxidative burst MIF of PMA-stimulated neutrophils and ALT and AST levels (r -0.35, P<0.05;r-0.4, P<0.03). sVCAM-1, sICAM-1, sE-selectin concentrations correlated negatively with the oxygen free radical production (MIF of R123) in neutrophils after PMA stimulation in liver cirrhosis patients (r-0.45, P<0.05;r-0.41, P<0.05; r-0.39, P<0.05, respectively).CONCLUSION: Neutrophil metabolic activity diminishes together with the intensification of liver failure. The metabolic potential of phagocytizing neutrophils is significantly lower in liver cirrhosis patients, which can be one of the causes of immune mechanism damage. The evaluation of oxygen metabolism of E. coli-stimulated neutrophils reveals that the amount of released oxygen metabolites is smaller in liver cirrhosis patients than in healthy subjects. | Anatol Panasiuk Jolanta Wysocka Elzbieta Maciorkowska Bozena Panasiuk Danuta Prokopowicz Janusz Zak Karol Radomski | 2005 | World Journal of Gastroenterology2005，11，48： | 4 |
| 8 | 弗兰克氏菌的G+C含量和DNA杂交显示文摘对一些弗兰克氏菌的遗传和生理特性进行了研究。结果表明,7株菌可以分为3个基因群。从木麻黄(casuarina equisetifolia)分离的菌株可以划为一个基因群(与菌株 S-103的DNA 同源性在74%以上),这是国外尚未报道的新基因群。其他两株弗兰克氏菌菌株 Arl4(从赤杨根瘤分离)和 PtI1(从 Purshia 根瘤分离)分别形成另外两个基因群,这与 An 的报道一致。7株弗兰克氏菌 DNA 的 G+c mol%在69—73。S-103基因群菌株不利用糖类,仅利用简单的有机酸盐。而菌株 Arl4和 PtI1则利用一些糖和有机酸盐作为碳源。 | 石彦林 阮继生 Jolanta Zakrzewska-Czerwinska Marian Mordarski | 1992 | 微生物学报1992，32，2： | 3 |
| 9 | A Contribution to Identification of Novel Regulators of Plant Response to Sulfur Deficiency: Characteristics of a Tobacco Gene UP9C, Its Protein Product and the Effects of UP9C Silencing显示文摘在植物 transcriptome 和 metabolome 的广泛的变化被众多的研究组在从最佳的条件把植物转移到硫(S) 缺乏以后观察了。尽管有集中的研究和最近的重要成就,作为对 S 缺乏的反应的一个主要 transcriptional 管理者喜欢 SLIM1/EIL3 的鉴定,有关规章的网络的另外的元素的许多问题仍然保持未答复。有编码未知功能力量的蛋白质的 S 缺乏应力调整的表示的基因的调查帮助澄清这些问题。这研究在烟草集中于 UP9C 基因和象 UP9 一样家庭。这些基因的相当或相同的事物在另外的植物种类存在,包括在 Arabidopsis thaliana (LSU1-4 ) 的未知功能的四基因的一个家庭,哪个当强烈由盐应力和硝酸盐限制由 S 赤字并且到更小的程度导致了,二被报导。预言的结构的特征的保存例如卷的卷区域或原子本地化信号,建议这些蛋白质可能可能有重要函数由和另外的蛋白质的相互作用调停了。有象 UP9 一样基因的 silenced 表示的转基因的烟草植物的分析强烈在对 S 赤字的植物反应的规定为他们的重要角色争论。尽管我们的学习证明象 UP9 一样蛋白质是如此的反应的重要部件,他们可能也在另外的压力期间被要求,他们的分子的功能仍然是一个谜。 | Matgorzata Lewandowska Anna Wawrzyhska Grzegorz Moniuszko Jolanta Lukomska Katarzyna Zientara Marta Piecho Pawel Hodurek Igor Zhukov Frantz Liszewska Victoria Nikiforova Agnieszka Sirko | 2010 | Molecular Plant2010，3，2： | 3 |
| 10 | Aminopolycarboxylic acid functionalized adsorbents for heavy metals removal from water显示文摘 | Eveliina Repo Jolanta K. Warcho? Amit Bhatnagar Ackmez Mudhoo Mika Sillanp?? | 2013 | Water Research2013，，： | 2 |
| 11 | Interferon γ Induces Translocation of Commensal Escherichia coli Across Gut Epithelial Cells via a Lipid Raft--Mediated Process显示文摘 | Edwin Clark Catherine Hoare Jolanta Tanianis-Hughes Gordon L. Carlson Geoffrey Warhurst | 2005 | Gastroenterology2005，，5： | 2 |
| 12 | Maturation, proliferation and apoptosis of seminal tubule cells at puberty after administration of estradiol, follicle stimulating hormone or both显示文摘瞄准:为了在雌二醇,滤泡刺激荷尔蒙(FSH ) 或两个代理人的影响下面在新生的老鼠在与 Sertoli 房间成熟的关系估计增生的和生精的上皮房间的 apoptotic 潜力,一起给。方法:从出生后的白天(PND ) , 5 ~ 15 只雄的老鼠每天与 17 β - estradiol (EB ) 的 12.5 μ g 被注射或人的 7.5 IU 净化了 FSH (hFSH )( 控制) 或 EB + hFSH 或溶剂。在出生后的白天 16,尸体被执行。Sertoli 房间成熟 / 功能被形态测定法估计。生精的上皮房间的增长是用免疫评估的份量上对增殖的房间的组织化学的标记用 TUNEL 方法的原子抗原和 apoptosis。结果:尽管 EB 禁止了 Sertoli 房间成熟, hFSH 不是有效的, Sertoli 房间成熟的显著加速发生在 EB + hFSH 以后。而 hFSH 刺激了 Sertoli 房间增长, EB 或 EB + hFSH 禁止了 Sertoli 房间增长。所有处理显著地刺激了细菌房间增长。Sertoli 房间的 Apoptosis 在 EB 以后增加了 9 褶层和生殖细胞 2 褶层,并且没被 hFSH 影响,但是在 EB + hFSH 以后被禁止。结论:在发身,雌二醇禁止 Sertoli 房间成熟,增加 Sertoli 和细菌房间 apoptosis,但是刺激细菌房间增长。在有 FSH 的协同的雌二醇,而是两荷尔蒙独自一个,加速与细菌房间幸存的增加联系的 Sertoli 房间成熟。雌二醇和 FSH 合作导致精液的小管成熟并且触发第一精子发生。 | Renata Walczak-Jedrzejowska Jolanta Slowikowska-Hilczer Katarzyna Marchlewska Krzysztof Kula | 2008 | Asian Journal of Andrology2008，10，4： | 2 |
| 13 | 芳香疗法对动脉压过高的治疗作用——前瞻性临床研究显示文摘使用依兰依兰油、甘牛至油和香紫苏油对动脉压过高的病人进行芳香疗法按摩治疗 ,通过问卷调查表统计结果 ,考察其临床降压疗效。结果证明 ,芳香疗法按摩具有可使过高的血压逐渐降低的作用。 | Jolanta Basnyet 李宏 | 2002 | 香料香精化妆品2002，，6： | 2 |
| 14 | Diagnostic accuracy of serum biochemical fibrosis markers in children with chronic hepatitis B evaluated by receiver operating characteristics analysis显示文摘AIM: To investigate the diagnostic accuracy of potent serum biochemical fibrosis markers in children with chronic hepatitis B evaluated by receiver operating characteristics (ROC) analysis.METHODS: We determined the serum level of apolipoprotein A-I (APO A-I), haptoglobin (HPT) and a-2macroglobulin (A2M) with an automatic nephelometer in 63 children (age range 4-17 years, mean 10 years)with biopsy-verified chronic HBeAg-positive hepatitis B.Fibrosis stage and inflammation grade were assessed in a blinded fashion according to Batts and Ludwig. We defined mild liver fibrosis as a score ≤2 and advanced fibrosis as a score equal to 3. ROC analysis was used to calculate the power of the assays to detect advanced liver fibrosis (AccuROC, Canada).RESULTS: Serum concentrations of APO A-I, HPT and A2M were not significantly different in patients with chronic hepatitis B compared to controls. However, APO A-I level of 1.19 ng/L had a sensitivity of 85.7% and a specificity of 60.7% (AUC = 0.7117, P = 0.035) to predict advanced fibrosis. All other serum biochemical markers and their combination did not allow a useful prediction.None of these markers was a good predictor of histologic inflammation.CONCLUSION: Apolipoprotein A-I may be a suitable serum marker to predict advanced liver fibrosis in children with chronic hepatitis B. | Dariusz Marek Lebensztejn Elzbieta Skiba Jolanta Tobolczyk Maria Elzbieta Sobaniec-Lotowska Maciej Kaczmarski | 2005 | World Journal of Gastroenterology2005，11，45： | 2 |
| 15 | ETM study of electroporation influence on cell morphology in human malignant melanoma and human primary gingival fibroblast cells显示文摘Objective:To estimate electroporation(EP) influence on malignant and normal cells.Methods: Two cell lines including human malignant melanoma(Me-43) and normal human gingival fibroblast(HCFs) were used.EP parameters were the following:230,1000,1 730,2 300 V/cm;30 μ s by 3 impulses for every case.The viability of cells after EP was estimated by MTT assay. The ullrastructural analysis was observed by transmission electron microscope(Zeiss EM 900). Results:In the current study we observed the intracellular effect following EP on Me-43 and HGF cells.At the conditions applied,we did not observe any significant damage of mitochondrial activity in both cell lines treated by EP.Conversely,we showed that EP in some conditions can stimulate cells to proliferation.Some changes induced by EP were only visible in electron microscopy.In fibroblast cells we observed significant changes in lower parameters of EP(230 and 1 000 V/cm).After applying higher electric field intensities(2 300 V/cm) we detected many vacuoles,myelin-like bodies and swallowed endoplasmic reticulum.In melanoma cells such strong pathological modifications after EP were not observed,in comparison with control cells. The ultrastructure of both treated cell lines was changed according to the applied parameters of EP.Conclusions:We can claim that EP conditions are cell line dependent.In terms of the intracellular morphology,human fibroblasts are more sensitive to electric field as compared with melanoma cells.Optimal conditions should be determined for each cell line.Summarizing our study,we can conclude that EP is not an invasive method for human normal and malignant cells. This technique can be safely applied in chemotherapy for delivering drugs into tumor cells. | Nina Skolucka Malgorzata Daczewska Jolanta Saczko Agnieszka Chwilkowska Anna Choromanska Malgorzata Kotulska Iwona Kaminska Julita Kulbacka | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，2： | 2 |
| 16 | The migration of bone marrow-derived non-hematopoietic tissue-committed stem cells is regulated in an SDF-1-, HGF-, and LIF-dependent manner显示文摘 | Magda Kucia Wojtek Wojakowski Ryan Reca Bogdan Machalinski Jolanta Gozdzik Marcin Majka Jarek Baran Janina Ratajczak Mariusz Z. Ratajczak | 2006 | Archivum Immunologiae et Therapiae Experimentalis2006，，2： | 2 |
| 17 | Calcium-Channel Blockers Reduce the Antiplatelet Effect of Clopidogrel显示文摘 | Jolanta M. Siller-Matula Irene Lang Guenter Christ Bernd Jilma | 2008 | Journal of the American College of Cardiology2008，，19： | 2 |
| 18 | A Functional Polymorphism of Toll-Like Receptor 4 Gene Increases Risk of Gastric Carcinoma and Its Precursors显示文摘 | Georgina L. Hold Charles S. Rabkin Wong–Ho Chow Malcolm G. Smith Marilie D. Gammon Harvey A. Risch Thomas L. Vaughan Kenneth E.L. McColl Jolanta Lissowska Witold Zatonski Janet B. Schoenberg William J. Blot N. Ashley G. Mowat Joseph F. Fraumeni Emad M. El | 2007 | Gastroenterology2007，，3： | 2 |
| 19 | Factors associated with intensification of antihypertensive drug therapy in patients with poorly controlled hypertension显示文摘Objective To assess antihypertensive management of older patients with poor blood pressure(BP)control.Methods Physicians,voluntary participating in the study,included six consecutive hypertensive patients during routine visits.Hypertension had to have been previously recognized and averaged office BP was>140 and/or>90 mmHg in spite of>6 weeks of antihypertensive therapy.The physicians completed a questionnaire on patients'history of cardiovascular(CV)risk factors,comorbidities,home BP monitoring,anthropometric data and the pharmacotherapy.Results Mean age of the 6462 patients was 61 years,7%were>80 years,51%were female.Mean士SD office BP values were 158士13/92土10 mmHg.The most commonly prescribed antihypertensive drugs were:diuretics(67%),ACE inhibitors(64%),calcium channel blockers(58%)and卩-blockers(54%),and their use increased with age.On monotherapy or dual therapy,43%of the patients and 40%had their latest treatment modification within six months.Home BP monitoring was a factor that accelerated the modification of the therapy.Older patients had to have less chance on faster modification of antihypertensive therapy in spite of presence of diabetes and higher systolic BP.Conclusions Our study suggests that a large number of outpatients with poor BP control receive suboptimal antihypertensive therapy,especially in primary care.In older patients,higher BP values in the office settings are more frequently accepted by physicians even in case of higher CV risk.Regular home BP monitoring hastens the decision to intensify of antihypertensive treatment. | Olga Siga Barbara Wizner Barbara Gryglewska Jolanta Walczewska Tomasz Grodzicki | 2019 | Journal of Geriatric Cardiology2019，16，1： | 2 |
| 20 | A comprehensive analysis of common genetic variation in MUC1 , MUC5AC , MUC6 genes and risk of stomach cancer显示文摘 | Yanbin Jia Christina Persson Lifang Hou Zongli Zheng Meredith Yeager Jolanta Lissowska Stephen J. Chanock Wong-Ho Chow Weimin Ye | 2010 | Cancer Causes & Control2010，，2： | 1 |
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