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4篇 您的检索式:作者名="Jorge McCormack"
    题名 作者 年代 出处 被引量
1Fatty liver disease,an emerging etiology of hepatocellular carcinoma in Argentina显示文摘AIM To investigate any changing trends in the etiologies of hepatocellular carcinoma(HCC) in Argentina during the last years. METHODS A longitudinal cohort study was conducted by 14 regional hospitals starting in 2009 through 2016. All adult patients with newly diagnosed HCC either with pathology or imaging criteria were included. Patients were classified as presenting non-alcoholic fatty liver disease(NAFLD) either by histology or clinically, provided that all other etiologies of liver disease were ruled out, fatty liver was present on abdominal ultrasound and alcohol consumption was excluded. Complete follow-up was assessed in all included subjects since the date of HCC diagnosis until death or last medical visit.RESULTS A total of 708 consecutive adults with HCC were included. Six out of 14 hospitals were liver transplant centers(n = 484). The prevalence of diabetes mellitus was 27.7%. Overall, HCV was the main cause of liver disease related with HCC(37%) including cirrhotic and non-cirrhotic patients, followed by alcoholic liver disease 20.8%, NAFLD 11.4%, cryptogenic 9.6%, HBV 5.4% infection, cholestatic disease and autoimmune hepatitis 2.2%, and other causes 9.9%. A 6-fold increase in the percentage corresponding to NAFLDHCC was detected when the starting year, i.e., 2009 was compared to the last one, i.e., 2015(4.3% vs 25.6%; P < 0.0001). Accordingly, a higher prevalence of diabetes mellitus was present in NAFLD-HCC group 61.7% when compared to other than NAFLD-HCC 23.3%(P < 0.0001). Lower median AFP values at HCC diagnosis were observed between NAFLD-HCC and non-NAFLD groups(6.6 ng/m L vs 26 ng/m L; P = 0.02). Neither NAFLD nor other HCC etiologies were associated with higher mortality.CONCLUSION The growing incidence of NAFLD-HCC documented in the United States and Europe is also observed in Argentina, a confirmation with important Public Health implications.Federico Pinero Josefina Pages Sebastián Marciano Nora Fernández Jorge Silva Margarita Anders Alina Zerega Ezequiel Ridruejo Beatriz Ameigeiras Claudia D’Amico Luis Gaite Carla Bermúdez Manuel Cobos Carlos Rosales Gustavo Romero Lucas McCormack Virginia Reggiardo Luis Colombato Adrián Gadano Marcelo Silva 2018World Journal of Hepatology2018,10,1:4
2Partial left lateral segment transplant from a living donor显示文摘Eduardo de Santibanes Lucas McCormack Juan Mattera Juan Pekol Jorge Sívori Axel Beskow Daniel Dagostino Miguel Ciardullo 2000Liver Transplantation2000,,1:1
3α肾上腺素能激动剂的变时性成熟性变化显示文摘应用不同浓度的α肾上腺素能激动剂和阻滞剂对比观察新生犬心脏的变时性效应。实验结果证明新生犬心脏的变时性效应发生成熟性变化。徐惠 Henry Gelband Jorge McCormack Arthur S. Pickoff Adrienne Stolfi 1989中国医科大学学报1989,18,4:0
4α受体阻滞剂对犬心脏电生理效应的研究显示文摘离体研究曾报道α肾上腺素受体对成年犬心脏有抑制作用,而对新生犬的心肌可能引起兴奋作用。为了确定α肾上腺受体阻滞剂对生体的电生理效应是否有年龄相关的差异,于新生犬和成年犬进行电生理研究。结果:伍用肾上腺素能和副交感神经阻滞剂后新生犬的心率明显下降,成年犬则无反应。心房有效不应期和功能不应期两组均延长。在新生犬组ARP的幅度明显增加。新生犬的VERP和VFRP明显延长。徐惠 Henry Gelband Jorge McCormack Arthur S Pickoff Adrienne Stolfi 1989中国医科大学学报1989,18,6:0
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