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| 1 | Higher education and graduate employment in Spain显示文摘 | Jose Gines Mora Jose Garcia Montalvo Adela Garcia Aracil | 2000 | European Journal of Education2000,,2: | 1 |
| 2 | The Origin of the Spinal Subdural Space:Ultrastructure Findings显示文摘 | Miguel Angel Reina MD Oscar De Leon Casasola MD Andres Lopez MD Jose Antonio De Andres MD Miguel Mora MD and Agustin Fernandez MD | 2002 | Anesth Analg2002,94,4: | 1 |
| 3 | Processing of high resolution magic angle spinning spectra of breast cancer cells by the filter diagonalization method显示文摘 | Maria RM Moraes TB Magon Claudio Jose | | 0,,19: | 1 |
| 4 | Biological control of Bradysi amatogrossemia (Diptera: Sciaridae)in mushroom cultivation with predatory mites显示文摘 | Renata Angelica Prado Freire Gilberto Jose de Moraes Edmilson Santos Silva | 2007 | Exp Appl Acarol2007,42,: | 1 |
| 5 | Optimization of wind farm tur-bines layout using an evaluative algorithm显示文摘 | Javier Serrao Gonzalez Angel G Gonzalez Rodriguez Jose Castro Mora | 2010 | Renewable energy2010,35,: | 1 |
| 6 | Effects of Molybdenum, Nickel, and Nitrogen Sources on the Mineral Nutrition and Growth of Rice Plants显示文摘 | Milton Ferreira Moraes Andre Rodrigues Reis Larissa Alexandra C. Moraes Jose Lavres-Junior Rafael Vivian Cleusa Pereira Cabral Euripedes Malavolta | 2009 | Communications in Soil Science and Plant Analysis (-)2009,,21: | 1 |
| 7 | Pho- tonic microwave tunable single-bandpa-ss filter based on a Mach-Zehnder interferometer 显示文摘 | Mora Jose Ortega Beatriz Diez Antonio | 2006 | IEEE Light- wave Technology2006,24,7: | 1 |
| 8 | Biological control of Bradysia matogrossensis (Diptera: Sciaridae) in mushroom cultivation with predatory mites显示文摘 | Renata Angelica Prado Freire Gilberto Jose Moraes Edmilson Santos Silva Alcione Cicera Vaz Raphael Campos Castilho | 2007 | Experimental and Applied Acarology2007,,2: | 1 |
| 9 | An evolutive algorithm for wind farm optimal design 显示文摘 | Jose Castro Mora Jose M Calero Baron | 2007 | Neurocomputing2007,70,16: | 1 |
| 10 | Micro-wave photonic signal processing 显示文摘 | Jose Capmany Jose Mora Ivana Gasulla | 2013 | Journal of Light-wave Technology2013,31,: | 1 |
| 11 | Optimization of wind farm turbines layout using an evolutivealgorithm显示文摘 | Javier serrao Gonzalez angel G Gonzalez Jose Castro Mora | 2010 | Renewable energy2010,35,8: | 1 |
| 12 | Higher education and graduate employment in Spain显示文摘 | JOSE-GINES MORA JOSE GARCIA-MONTALVO ADELA GARCIA-ARACIL | 2000 | European Journal of Education2000,35,2: | 1 |
| 13 | Temperature sensor based on the power reflected by a Bragg grating in a tapered fiber显示文摘 | Hernandez D M Mora Jose Perez-Millan Pere | 2004 | Applied Optics2004,43,12: | 1 |
| 14 | Removal of Iron from Molten Recycled Aluminum through Intermediate Phase Flitration 显示文摘 | Humberto Lopes de Moraes Jose Roberto de Oliveira Denise Crocce Romano Espinosa | 2006 | Materials Transactions2006,47,7: | 1 |
| 15 | Prevalence of hepatitis C infection in patients with non-Hodgkin’s lymphomas显示文摘 | Maria Chindamo Nelson Spector Jorge Segadas Glicinia Pimenta Bart Vanderborght Jose Morais Cristiane Milito Henrique Moraes Coelho | 2002 | Oncology Reports2002,,3: | 1 |
| 16 | Influence of agitation rate on the performance of an anaerobic sequencing batch reactor containing granulated bio- mass treating low - strength wastewater显示文摘 | Jose Alberto Domingues Rodrigues Suzana Mafia Ratusznei Eduardo Freitas Moraes de Camargo Marcelo Zaiat | 2003 | Advances in Environmental Research2003,7,: | 1 |
| 17 | XRD study of ZrW2O8 versus temperature and pressure显示文摘 | JOSE MANUEL GALLARDO-AMORES ULISES AMADOR EMILIO MORA' N | 2000 | International Journal of Inorganic Materials2000,2,: | 1 |
| 18 | Identification of primary and Secondary Measles Vaccine Failures by Measurement of Immunoglobulin G Avidity in Measles Cases during the 1997 Sao Paulo Epidemic显示文摘 | Claudio S Pannuti Ricardo Jose Morello Jose Cassio de Moraes | 2004 | Clin Diagn Lab Innunol2004,11,1: | 1 |
| 19 | Type 2 Diabetes, Alcoholism and Exposure to Biomass Smoke Are Risk Factors for Tuberculosis显示文摘 | Ma. Cecilia Garcia Sancho Ma. del Rosario Fernandez Plata Ma. Susana Rivera de la Garza Ma. De los ,Angeles Mora Pizano Jose Rogelio Perez-Padilla | 2010 | Journal of US-China Medical Science2010,7,9: | 0 |
| 20 | In Silico Pipeline to Identify Tumor‑Specific Antigens for Cancer Immunotherapy Using Exome Sequencing Data显示文摘Tumor-specific antigens or neoantigens are peptides that are expressed only in cancer cells and not in healthy cells.Some of these molecules can induce an immune response,and therefore,their use in immunotherapeutic strategies based on cancer vaccines has been extensively explored.Studies based on these approaches have been triggered by the current high-throughput DNA sequencing technologies.However,there is no universal nor straightforward bioinformatic protocol to discover neoan-tigens using DNA sequencing data.Thus,we propose a bioinformatic protocol to detect tumor-specific antigens associated with single nucleotide variants(SNVs)or“mutations”in tumoral tissues.For this purpose,we used publicly available data to build our model,including exome sequencing data from colorectal cancer and healthy cells obtained from a single case,as well as frequent human leukocyte antigen(HLA)class I alleles in a specific population.HLA data from Costa Rican Central Valley population was selected as an example.The strategy included three main steps:(1)pre-processing of sequencing data;(2)variant calling analysis to detect tumor-specific SNVs in comparison with healthy tissue;and(3)prediction and characterization of peptides(protein fragments,the tumor-specific antigens)derived from the variants,in the context of their affinity with frequent alleles of the selected population.In our model data,we found 28 non-silent SNVs,present in 17 genes in chromosome one.The protocol yielded 23 strong binders peptides derived from the SNVs for frequent HLA class I alleles for the Costa Rican population.Although the analyses were performed as an example to implement the pipeline,to our knowledge,this is the first study of an in silico cancer vaccine using DNA sequencing data in the context of the HLA alleles.It is concluded that the standardized protocol was not only able to identify neoantigens in a specific but also provides a complete pipeline for the eventual design of cancer vaccines using the best bioinformatic practices. | Diego Morazán‑Fernández Javier Mora Jose Arturo Molina‑Mora | 2023 | Phenomics2023,3,2: | 0 |