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| 1 | The influence of the Madden-Julian Oscillation activity anomalies on Yunnan's extreme drought of 2009-2010显示文摘Yunnan Province of China suffered a record-breaking drought that persisted from autumn 2009 into spring 2010. The present study examined the physical causes of this extreme drought event in terms of persistent anomalies of intraseasonal oscillation in the tropical atmosphere (the Madden-Julian Oscillation hereafter the MJO). The results show that the occurrence of severe drought in Yunnan was caused directly by deficient rainfall lasting from the summer of 2009 to the spring of 2010. Further exploration reveals a persistent positive variation of MJO index 1 from June to October. Accordingly, the convective activity over the Bay of Bengal (BOB) weakened continuously, and then an anomalous descending airflow was induced over the tropical Indian Ocean, resulted in the anomalous weakening of vertical Asian monsoon circulation in South Asia. Consequently, the transport of water vapor from the tropical Indian Ocean to Yunnan decreased abnormally, leading to persistent below-normal rainfall over Yunnan from summer to autumn in 2009. As a result, a severe drought began to appear in autumn. In the winter of 2009-2010, MJO index 1 remained persistently positive, indicating the continuous weakening of convective activity over the BOB. The atmospheric circulation associated with the persistent positive anomalies in the MJO also demonstrated anomalous patterns. Specifically, there was an anomalous high-pressure ridge stretching from South Asia through the Tibetan Plateau and into the western part of southwestern China. This indicates that the atmospheric circulation over Yunnan was dominated by vertical descending airflow in the high-pressure ridge. Simultaneously, the India-Burma trough was weakened, which resulted in unfavorable conditions for the transport of water vapor from the BOB to Yunnan, causing the observed persistent deficient precipitation in winter and the subsequently intensified drought. Therefore, the persistent anomalies in MJO activity in the tropical atmosphere played an important role in the occurrence of the extreme drought event in Yunnan in 2009-2010. | LU JunMei JU JianHua REN JuZhang GAN WeiWei | 2012 | Science China Earth Sciences2012，55，1： | 25 |
| 2 | A microarray-based gastric carcinoma prewarning system显示文摘AIM: To develop a microarray-based prewarning system consisting of gastric cancer chip, prewarning data and analysissoftware for early detection of gastric cancer and pre-cancerous lesions.METHODS: Two high-density chips with 8 464 human cDNA sites were used to primarily identify potential genes specific for normal gastric mucosa, pre-cancerous lesion and gastric cancer. The low-density chips, composed of selected genes associated with normal gastric mucosa,precancerous lesion and gastric cancer, were fabricated and used to screen 150 specimens including 60 specimens of gastric cancer, 60 of pre-cancerous tissues and 30 of normal gastric mucosa. CAD software was used to screen out the relevant genes and their critical threshold values of expression levels distinguishing normal mucosa from pre-cancerous lesion and cancer. All data were stored in a computer database to establish a prewarning data library for gastric cancer. Two potential markers brcaa1 and ndr1were identified by Western blot and immunohistochemistry.RESULTS: A total of 412 genes associated with three stages of gastric cancer development were identified.There were 216 genes displaying higher expression in gastric cancer, 85 genes displaying higher expression in pre-cancerous lesion and 88 genes displaying higher expression in normal gastric mucosa. Also 15 genes associated with metastasis of gastric cancer and 8 genes associated with risk factors were screened out for target genes of diagnosis chip of early gastric cancer. The threshold values of 412 selected genes to distinguish gastric cancer, pre-cancerous lesion from normal gastric mucosa were defined as 6.01±2.40, 4.86±1.94 and 5.42±2.17, respectively. These selected 412 genes and critical threshold values were compiled into an analysis software, which can automatically provide reports by analyzing the results of 412 genes obtained by examining gastric tissues. All data were compiled into a prewarning database for gastric cancer by CGO software. Northern blot and immunohistochemistry analysis confirmed that gene and protein of brcaa1 displayed lower expression in normal gastric mucosa and higher expression in gastric cancer tissues, conversely, ndr1 displayed lower expression in gastric cancer and higher expression in normal gastric mucosa.CONCLUSION: The microarray-based prewarning system for gastric cancer was developed. This system consisted of gastric cancer-associated gene chip, prewarning data and analysis software, which has a high potential for applications in the early detection of gastric cancer. The two potential markers brcaa1 and ndr1 identified may be used to distinguish cancer status fand non-cancer status. | Da-XiangCui LiZhang Xiao-JunYan Ling-XiaZhang Jun-RongXu Yan-HaiGuo Gui-QiuJin GiovaniGomez DingLi ,Jin-RongZhao Fen-ChanHan JuZhang Jia-LeHu Dai-MingFan Hua-JianGao | 2005 | World Journal of Gastroenterology2005，11，9： | 4 |
| 3 | Influence of Springtime Atlantic SST on ENSO:Role of the Madden-Julian Oscillation显示文摘Increased evidence has shown the important role of Atlantic sea surface temperature(SST) in modulating the El Nio-Southern Oscillation(ENSO). Persistent anomalies of summer Madden-Julian Oscillation(MJO) act to link the Atlantic SST anomalies(SSTAs) to ENSO. The Atlantic SSTAs are strongly correlated with the persistent anomalies of summer MJO, and possibly affect MJO in two major ways. One is that an anomalous cyclonic(anticyclonic) circulation appears over the tropical Atlantic Ocean associated with positive(negative) SSTA in spring, and it intensifies(weakens) the Walker circulation. Equatorial updraft anomaly then appears over the Indian Ocean and the eastern Pacific Ocean, intensifying MJO activity over these regions. The other involves a high pressure(low pressure) anomaly associated with the North Atlantic SSTA tripole pattern that is transmitted to the mid-and low-latitudes by a circumglobal teleconnection pattern, leading to strong(weak) convective activity of MJO over the Indian Ocean. The above results offer new viewpoints about the process from springtime Atlantic SSTA signals to summertime atmospheric oscillation, and then to the MJO of tropical atmosphere affecting wintertime Pacific ENSO events, which connects different oceans. | Xin YAN Juzhang REN Jianhua JU Song YANG | 2018 | Journal of Meteorological Research2018，32，3： | 1 |
| 4 | Characteristics of the Nujiang River runoff for a long term and its response to climate change显示文摘Nujiang 河流量每年,和流量从 5 月显然增加从 5 月在时期期间统治了 81.9% 粗野的年度列到 10 月,它是在这个区域上的雨季。吝啬的流量因此在雨季期间在每个月内说明 13.65% 年度列但是仅仅 3% 在旱季期间。在另一个词,在雨季的月经流量在另外的月内像乘那的 4.5 一样。它证明流量与季节极大地变化,在雨季的流量在年度列起主导的作用。在河流量和降水之间的关系的分析结果因为同步关联系数从 1 月是重要的到 4 月但是与 1 个月的关联除了在 7 月,在另外的月内落后。基于在河流量上完成的降水的分析,在 5 月的降水极大地影响年度流量并且有一种靠近的关系到旱季,这被注意。年度,雨季和旱季流量和降水被小浪分析变换。结果证明降水和流量的变化与低频率变化(大约 24 年) 展出主导的时期,十(大约 8 年) 并且 interdecadal (大约 16 年) 摆动。变化年度,雨季和旱季流量与一个增加的趋势一致,除了在 6 月和 8 月,它与 0.05 信心水平是明显的。数据显示平均流量被 57.6, 28.1 和 85.7 m3/s 为年度列,旱季和雨季分别地在每 10 年里增加。最明显的变化在 10 月,它每 10 年增加了 111.3 m3/s。在 Nujiang 河排水盆的流量,温度和降水的变化主要是一致的。气候变化在 Nujiang 导致了流量变化,这被揭示。它在 10 月最大地被增加,第二,在 5 月和每年的增加数量,流量能完成大约 60 m3/s。在未来, 20 年,在早阶段的流量愿望减少,而是以后的增加分阶段执行。 | ZHANG WanCheng XIAO ZiNiu ZHENG JianMeng REN JuZhang | 2007 | Chinese Science Bulletin2007，52，A02： | 1 |
| 5 | Spontaneous Interspecific Hybridization and Patterns of Pollen Dispersal in Ex Situ Populations of a Tree Species (Sinojackia xylocarpa) that is Extinct in the Wild显示文摘 | JIN‐JUZHANG QI‐GANGYE XIAO‐HONGYAO HONG‐WENHUANG | 2010 | Conservation Biology2010，，1： | 1 |
| 6 | Cloning of HPV16 E2 Gene from a Biopsied Cervical Cancer Sample显示文摘To clone HPV16 E2 gene from a biopsied cervical cancer sample Materials & Methods HPV16 E2 gene was amplified from specimen derived from a HPV 16 positive patient, then cloned and sequenced. Results The full length of HPV 16 E2 gene was successfully cloned. In comparison with the prototype accepted by GenBank, six point mutations in HPV 16 E2 nucleotide acid sequence were identified. Of them, three were missense, and one was in the overlapping E4 gene and was synonymous to E4. Conclusion HPV16 E2 gene was successfully cloned, and some nucleotide acids in its sequence were different from the prototype. | Yan-eGAO JuZHANG Tian-baoSONG Xiao-junYAN | 2002 | Journal of Reproduction and Contraception2002，13，3： | 0 |
| 7 | APPROACH TO KARST SOLUTION PROCESS RESPONSES ON CLIMATE显示文摘Based upon the studies of solutional rates with environment from South China to North China over a range of about 30 。 latitude, this paper discusses some of the consequence with equations. The response model shows that the precipitation is the most important factor influencing the rate of solutional denudation except the lithology, the relief etc., but it is an integrational action on the solution process; at the same time, temperature acts as a threshold in bringing the precipitation into play. These suggest that firstly, the solutional denudation process is a comprehensive response to the multiple factors; secondly, karst solution is a complex response process to the climate, and as an integrated exogenic process under the bioclimate. | Lin Junshu Li Juzhang Fang Jinfu Institute of Geography, CAS, Beijing 100101 People’s Republic of China | 1997 | Journal of Geographical Sciences1997，7，3： | 0 |
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