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| 1 | Expression of nuclear factor-kappa B and target genes in gastric precancerous lesions and adenocarcinoma:Association with Helicobactor pylori cagA (+) infection显示文摘AIM:To examine the expression of nuclear factor kappaB (NF-κB) and its target genes in intestinal metaplasia (IM),dysplasia (DYS) and gastric carcinoma (GC) infected with Helicobacter pylori (H pylori) and to investigate the mechanism underlying Hpyloricytotoxin associated gene A(cag A) infection leading to gastric adenocarcinoma.METHODS: Expressions of NF-κB/p65 and its target genes:c-myc, cyclinD1 and bcl-xl were immunohistochemically examined in 289 cases of gastric biopsy and resection specimens from patients with IM, DYS and GC infected with H pylori. H pylori in the above mentioned tissues was detected by Warthin-Starry stain and rapid urease tests.IgG antibody to cagA in sera of the patients was measured by ELISA.RESULTS:The positive rates of NF-κB/p65 were significantly higher in groups with cagA of IMI-Ⅱ(28/33), IM III(48/52),DYSI(27/31), DY5 Ⅱ-Ⅲ(28/32), GC(35/40) than in groups without cagA of IMI-Ⅱ(4/17), IMⅢ(3/20), DYSI(3/20),DYSⅡ-Ⅲ(6/21), GC(10/23). The expressions of c-myc,cyclinD1, and bcl-xl were significantly higher in groups with cagA of IM Ⅲ(47/52, 49/52, 46/52), DYSⅡ-Ⅲ(29/32, 26/32,25/32) than in groups without cagA of IM Ⅲ(8/20, 7/20,5/20), DYSⅡ-Ⅲ(10/21, 8/21, 3/21), which were in conformity with the expression of NF-κB in IM Ⅲ, and DYSⅡ-Ⅲ. Asignificantly higher expression level of NF-κB/p65, c-myc,cyclinD1 and bcl-xl was detected in intestinal type GC(27/28,18/28, 22/28, 24/28) than in diffuse type GC(8/12, 3/12,3/12, 6/12), respectively.CONCLUSION: There may be two different molecular mechanisms in the occurrence of intestinal and diffuse type gastric carcinomas. Intestinal type gastric carcinoma is strongly associated with high expression of c-myc, cyclinD1 and bcl-xl through NF-κB/p65 activated by Hpylori cagA.Inhibiting the activity of NF-κB is an effective and promising way to prevent intestinal type gastric carcinoma. | Gui-FangYang Chang-ShengDeng Yong-YanXiong Ling-LingGong Bi-ChengWang JunLuo | 2004 | World Journal of Gastroenterology2004，10，4： | 27 |
| 2 | Electroless silver coating on fine copper powder and its effects on oxidation resistance显示文摘 | Xu Xinrui Xiao Junluo Zhuang Hanrui | 2003 | Mater Lett2003，57，： | 1 |
| 3 | A Method for Generating Super Large Fractal Images Useful for Decoration Art显示文摘Many authors have reported the techniques to iterate nonlinear equations oncomplex plane, but generally, the sise of image calculated by usual VGA style (640×480) istoo small to fit the needs for high quality publications or decorative patterus. We describea universal method for generating and storing (in *.GIF format) fractal forge large enoughas you need, such as an wie 5000×5000 256-color(25,000, 74 bytes 23.8MB), whichcan thoroughly display the intricate beauty of fractals. | HuajieLIU JunLUO | 1996 | Communications in Nonlinear Science and Numerical Simulation1996，1，3： | 1 |
| 4 | Liquid structure of pure iron by X-ray diffraction显示文摘The liquid structure of pure iron at 1540, 1560 and 1580℃ was studied by X-ray diffraction. The results show that near the melting point there is a medium-range order structure that fades away with the increasing temperature. The average nearest distance of atoms is almost independent of the melts temperature, but the average coordination number, the atom cluster size and the atom number in an atom cluster all decrease with the increasing temperature of the melt. Near the melting point there area lot of atom clusters in the pure iron melt. The atom cluster of pure iron has the body-centered cubic lattices, which are kept from the solid state. And the body-centered cubic lattices connect into network by occupying a same edge. The atoms in the surrounding of the atom clusters are arranged disorderly. | JunLuo QijieZhai PeiZhao XuboQin | 2004 | Journal of University of Science and Technology Beijing2004，11，2： | 0 |
| 5 | Severe burn of penis caused by excessive short-wave diathermy显示文摘Penis bum is not rare and usually caused by boiling water and fire. To our knowledge we report the first case of severe bum of penis secondary to excessive short wave diathermy. | JunJiang Fang-QiangZhu JunLuo Luo-FuWang QingJiang | 2004 | Asian Journal of Andrology2004，6，4： | 0 |
| 6 | Disk-like Tiles Derived from Complex Bases显示文摘For each positive integer k, the radix representation of the complex numbers in the base-κ + i gives rise to a lattice self-atone tile Tκ in the plane, which consists of all the complex numbersthat can be expressed in the form ∑j>1 dj(-κ + i)^-j, where dj ∈ {0, 1,2 , κ^2}. We prove that Tκ is homeomorphic to the closed unit disk {z ∈ C : |z| ≤ 1} if and only if k ≠ 2. | JunLUO ZuoLingZHOU | 2004 | Acta Mathematica Sinica,English Series2004，20，4： | 0 |
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