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2篇 您的检索式:作者名="Junqi Kuang"
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1Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation显示文摘Although monkeys and pigs can be infected with SARS-Co V-2,they generally have a long growth cycle and a large size that is difficult to handle in large quantities.However,the readily available rats and mice are not susceptible to SARSCo V-2 because of differences in ACE2(angiotensin-converting enzyme 2),the receptor mediating cell entry of SARSCo V-2[1].Thus,the key to establishing a mouse model of COVID-19 is to make the mice express human ACE2 protein,and therefore become SARS-Co V-2 susceptible.Recently reported COVID-19 mouse models using a random insertion transgene approach[2,3]or adenoviral approach to express h ACE2[4],lack the tissue-specificity of h ACE2 expression and might not replicate COVID-19 precisely,limiting their applications in certain studies.Feng-Liang Liu Kaixin Wu Jiaoyang Sun Zilei Duan Xiongzhi Quan Junqi Kuang Shilong Chu Wei Pang Han Gao Ling Xu Ying-Chang Li Hai-Lin Zhang Xue-Hui ang Rong-Hua Luo Xiao-Li Feng Hans RScholer Xinwen Chen Duanqing Pei Guangming Wu Yong-Tang Zheng Jiekai Chen 2021National Science Review2021,8,2:3
2诱导多能性干细胞过程中染色质可及性动态变化规律显示文摘文章简介关于体细胞重编程中染色质结构重排的机制一直没有被清晰地研究过。本研究通过采用可在全基因组范围内研究开放染色质的ATAC(Assay for Transposase-Accessible Chromatin)技术。李东伟 刘晶 杨雪洁 Chunhua Zhou Jing Guo Chuman Wu Yue Qin Lin Guo Jiangping He Shenyong Yu He Liu Xiaoshan Wang Fang Wu Junqi Kuang Andrew P.Hutchins 陈捷凯 裴端卿 2018科学新闻2018,0,4:0
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