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	题名	作者	年代	出处	被引量
1	Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters.	V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun	2003	World Journal of Gastroenterology2003，9，10：	5
2	Nodular Fasciitis of the Breast Previously Misdiagnosed as Breast Carcinoma显示文摘	Ozben V Aydogan F Karaca FC	2009	Breast Care (Basel)2009，4，6：	1
3	Protective effectsof erythropoietin on ischemia/reperfusion injury of rat ovary显示文摘	Karaca M Odabasoglu F Kumtepe Y	2009	Eur J Obstet Gynecol Reprod Biol2009，144，2：	1
4	Influence of fumigation with high concentrations of ozone gas on postharvest gray mold and fungicide residues on table grapes显示文摘	Gabler F M Smilanick J L Mansour M F Karaca H	2010	Postharvest Biology and Technology2010，55，2：	1
5	Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway显示文摘	CHOI S S SYN W K KARACA G F	2010	J Biol Chem2010，285，36：	1
6	High risk of pituitarydysfunction due to aneurismal subarachnoid haemorrhage : aprospective investigation of anterior pituitary function in the acutephase and 12 months after the event 显示文摘	Tanriverdi F Dagli AT Karaca Z	2007	Clin Endocrinol ( Oxf)2007，67，6：	1
7	Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steato- hepatitis 显示文摘	Witek R P Stone W C Karaca F G	2009	Hepatol2009，50，5：	1
8	Pregnancy and pituitary disorders 显示文摘	Karaca Z Tanriverdi F Unluhizarci K	2010	Eur J Endocrinol2010，162，9：	1
9	Empty sella may be the final outcome in lymphocytic hypophysitis 显示文摘	KARACA Z TANRIVERDI F UNLUHIZARCI K	2009	Endocr Res2009，34，12：	1
10	Central composite rotatable design for liquefaction of pine barks显示文摘	ACIKALIN K KARACA F BOLAT E	2005	Fuel Process Technol2005，87，1：	1
11	Molecular mass distribution and structural characterization of liquefaction production of a biomass waste material显示文摘	KARACA F	2006	Energy Fuels2006，20，1：	1
12	Statistical Modeling for Selecting Housekeeper Genes 显示文摘	Aniko Szabo Charles M Perou Mehmet Karaca Laurent Perreard John F Quackenbush Philip S Bernard	2004	Genome Biology2004，5，8：	1
13	Hypopituitarism due to sports related head trauma and the effects of growth hormone replacement in retired amateur boxers显示文摘	Tanriverdi F Unluhizarci K Karaca Z	2010	Pituitary2010，13，2：	1
14	The effects of di?etary organic Or inorganic selenium in rainbow trout (On?corhynchus mykiss) under crowding conditions显示文摘	Kucukbay F Z Yazlak 1-1 Karaca I	2009	Aquacul?ture Nutrition2009，15，：	1
15	Nodular fasciitis of the breast previously misdiagnosed as breast carcinoma显示文摘	Ozben V Aydogan F Karaca FC	2009	Breast Care (Basel)2009，4，6：	1
16	Ground level ozone exposure and distributionover the historical Peninsula of Istanbul显示文摘	Karaca F Oztiirk Z	2012	Journal of CulturalHeritage2012，13，1：	1
17	Molecular Mass Ranges of Coal Tar Pitch Fractions by Mass Spectrometry and Size-exclusion Chromatography显示文摘	Karaca F Morgan T 3 George A	2009	Rapid Communications in Mass Spectrometry2009，23，13：	1
18	Determination of petroleum-degrading bacteria isolated from crude oil-contaminated soil in Turkey显示文摘	Erdoan E E ahin F Karaca A	2012	Afr J Biotech2012，11，21：	1
19	Coprocessing of a Turkish lignite with a cellulosic waste material: 1 The effect of coprocessing on liquefaction yields at different reaction temperatures 显示文摘	KARACA F BOLAT E	2000	Fuel Process Technol2000，64，13：	1
20	Coprocessing of a Turkish lignite with a cellulosic waste material : 2 The effect of coprocessing on liquefaction yields at different reaction pressures and sawdust/lignite ratios 显示文摘	KARACA F BOLAT E	2002	Fuel Process Technol2002，75，2：	1

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