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| 1 | Aspirin use for primary prophylaxis: Adverse outcomes in non-variceal upper gastrointestinal bleeding显示文摘AIM: To compare outcomes of patients with nonvariceal upper gastrointestinal bleeding(NVUGIB) taking aspirin for primary prophylaxis to those not taking it.METHODS: Patients not known to have any vascular disease(coronary artery or cerebrovascular disease) who were admitted to the American University of Beirut Medical Center between 1993 and 2010 with NVUGIB were included. The frequencies of in-hospital mortality, re-bleeding, severe bleeding, need for surgery or embolization, and of a composite outcome defined as the occurrence of any of the 4 bleeding related adverse outcomes were compared between patients receiving aspirin and those on no antithrombotics. We also compared frequency of in hospital complications and length of hospital stay between the two groups.RESULTS: Of 357 eligible patients, 94 were on aspirin and 263 patients were on no antithrombotics(controlgroup). Patients in the aspirin group were older, the mean age was 58 years in controls and 67 years in the aspirin group(P < 0.001). Patients in the aspirin group had significantly more co-morbidities, including diabetes mellitus and hypertension [25(27%) vs 31(112%) and44(47%) vs 74(28%) respectively,(P = 0.001)], as well as dyslipidemia [21(22%) vs 16(6%), P < 0.0001).Smoking was more frequent in the aspirin group [34(41%) vs 60(27%), P = 0.02)]. The frequencies of endoscopic therapy and surgery were similar in both groups. Patients who were on aspirin had lower inhospital mortality rates(2.1% vs 13.7%, P = 0.002),shorter hospital stay(4.9 d vs 7 d, P = 0.01), and fewer composite outcomes(10.6% vs 24%, P = 0.01). The frequencies of in-hospital complications and re-bleeding were similar in the two groups.CONCLUSION: Patients who present with NVUGIB while receiving aspirin for primary prophylaxis had fewer adverse outcomes. Thus aspirin may have a protective effect beyond its cardiovascular benefits. | Karina M Souk Hani M Tamim Hussein A Abu Daya Don C Rockey Kassem A Barada | 2016 | World Journal of Gastrointestinal Surgery2016，8，7： | 3 |
| 2 | Production of human papillomavirus type 16 L1 virus-like particles by recombinant Lactobacillus casei cells 显示文摘 | Karina A A Aurora M C Sylvia M C | 2006 | Appl Envir2006，72，1： | 1 |
| 3 | Psychiatric comorbiclity in anorexia and bulimia nervosa : nature, prevalence, and causal relationships 显示文摘 | Karina M C)'Brien | 2003 | Clin Psychol Rev2003，23，： | 1 |
| 4 | Vaciine with the recombinant Brucella outer membrane protein 31 or derived 27-amino-acid synthetic peptide elicits a CD4-T helper 1 response that protects against Brucella melitensis infection显示文摘 | Juliana C T Silvia M E Karina A P | 2005 | Infect Immun2005，73，12： | 1 |
| 5 | Seed rain and seed limitation in a planted gallery forest in Brazil 显示文摘 | Karina C B Marco A P | 2006 | Restoration Ecology2006，14，4： | 1 |
| 6 | Production of human papillomavirus type 16 L1 virus-like particles by recombinant lactobacillus casei cells显示文摘 | Karina A A Aurora M C Sylvia M C | 2006 | Applied and Environmental Microbiology2006，72，1： | 1 |
| 7 | Phar- macokinetics of dalteparin during haemodialysis显示文摘 | Jeannet Nigten Karina A De Groot Diana C | 2013 | Ne- phron Clinical Practice2013，124，4： | 1 |
| 8 | CD133 identifies perivascular niches in grade Ⅱ-Ⅳ astrocytomas显示文摘 | Karina C Henrik D Schroder B | 2008 | Neurooncol2008，6，20： | 1 |
| 9 | Viability of Lacto- bacillus acidophilus La5 in pectin whey protein microparticles during exposure to simulated gastrointestinal conditions显示文摘 | CLAIKICE G KARINA S C MARIA C E | 2013 | Food Research In- ternational2013，51，： | 1 |
| 10 | Diace RH downregulate proinflammatory cytokines expression and decrease the autoimmune diabetes frequency in nonobese diabetic (NOD) mice 显示文摘 | CARINA M CONCEI C AO A V KARINA P V | 2008 | International Immunopharmacology2008，8，6： | 1 |
| 11 | Further validation of the HPCDtechnique for the evaluation of PAH microbial availability in soil显示文摘 | Kieren J D Paula J C Karina U | 2006 | Environmental Pollution2006，144，： | 1 |
| 12 | Seed Rain and Seed Limitation in a PlantedGallery Forest in Brazil显示文摘 | Karina C B Marco A P | 2006 | Restoration Ecology2006，14，4： | 1 |
| 13 | Programmed death l ligand signaling regulates the generation of adaptive Foxp3 + CD4 + regulatory T ceils显示文摘 | Li Wang Karina Pino-Lagos Victor C | 2008 | Pine Natl Aead Sei USA2008，105，27： | 1 |
| 14 | Anti-HIV prenylated flavoids from Monotes africanus 显示文摘 | Karina M Meragelman Tawnya C | 2001 | J Nat Prod2001，64，： | 1 |
| 15 | Antibody reactivity to omp31 from Brucella melitensis in human and animal infections by smooth and rough Brucellae 显示文摘 | Juliana C Karina P Laura B | 2004 | Clinical and Vaccine Immu- nology2004，11，1： | 1 |
| 16 | FungalTraits:a user-friendly traits database of fungi and fungus-like stramenopiles显示文摘The cryptic lifestyle of most fungi necessitates molecular identification of the guild in environmental studies.Over the past decades,rapid development and affordability of molecular tools have tremendously improved insights of the fungal diversity in all ecosystems and habitats.Yet,in spite of the progress of molecular methods,knowledge about functional properties of the fungal taxa is vague and interpretation of environmental studies in an ecologically meaningful manner remains challenging.In order to facilitate functional assignments and ecological interpretation of environmental studies we introduce a user friendly traits and character database FungalTraits operating at genus and species hypothesis levels.Combining the information from previous efforts such as FUNGuild and FunFun together with involvement of expert knowledge,we reannotated 10,210 and 151 fungal and Stramenopila genera,respectively.This resulted in a stand-alone spreadsheet dataset covering 17 lifestyle related traits of fungal and Stramenopila genera,designed for rapid functional assignments of environmental stud-ies.In order to assign the trait states to fungal species hypotheses,the scientific community of experts manually categorised and assigned available trait information to 697,413 fungal ITS sequences.On the basis of those sequences we were able to summarise trait and host information into 92,623 fungal species hypotheses at 1%dissimilarity threshold. | Sergei Põlme Kessy Abarenkov RHenrik Nilsson Björn D.Lindahl Karina Engelbrecht Clemmensen Havard Kauserud Nhu Nguyen Rasmus Kjøller Scott T.Bates Petr Baldrian Tobias Guldberg Frøslev Kristjan Adojaan Alfredo Vizzini Ave Suija Donald Pfister Hans-Otto Baral Helle Järv Hugo Madrid Jenni Nordén Jian-Kui Liu Julia Pawlowska Kadri Põldmaa Kadri Pärtel Kadri Runnel Karen Hansen Karl-Henrik Larsson Kevin David Hyde Marcelo Sandoval-Denis Matthew E.Smith Merje Toome-Heller Nalin N.Wijayawardene Nelson Menolli Jr Nicole K.Reynolds Rein Drenkhan Sajeewa S.N.Maharachchikumbura Tatiana B.Gibertoni Thomas Læssøe William Davis Yuri Tokarev Adriana Corrales Adriene Mayra Soares Ahto Agan Alexandre Reis Machado Andrés Argüelles-Moyao Andrew Detheridge Angelina de Meiras-Ottoni Annemieke Verbeken Arun Kumar Dutta Bao-Kai Cui C.K.Pradeep César Marín Daniel Stanton Daniyal Gohar Dhanushka N.Wanasinghe Eveli Otsing Farzad Aslani Gareth W.Griffith Thorsten H.Lumbsch Hans-Peter Grossart Hossein Masigol Ina Timling Inga Hiiesalu Jane Oja John Y.Kupagme József Geml Julieta Alvarez-Manjarrez Kai Ilves Kaire Loit Kalev Adamson Kazuhide Nara Kati Küngas Keilor Rojas-Jimenez Krišs Bitenieks Laszlo Irinyi LászlóGNagy Liina Soonvald Li-Wei Zhou Lysett Wagner M.Catherine Aime MaarjaÖpik María Isabel Mujica Martin Metsoja Martin Ryberg Martti Vasar Masao Murata Matthew PNelsen Michelle Cleary Milan C.Samarakoon Mingkwan Doilom Mohammad Bahram Niloufar Hagh-Doust Olesya Dulya Peter Johnston Petr Kohout Qian Chen Qing Tian Rajasree Nandi Rasekh Amiri Rekhani Hansika Perera Renata dos Santos Chikowski Renato L.Mendes-Alvarenga Roberto Garibay-Orijel Robin Gielen Rungtiwa Phookamsak Ruvishika S.Jayawardena Saleh Rahimlou Samantha C.Karunarathna Saowaluck Tibpromma Shawn P.Brown Siim-Kaarel Sepp Sunil Mundra Zhu-Hua Luo Tanay Bose Tanel Vahter Tarquin Netherway Teng Yang Tom May Torda Varga Wei Li Victor Rafael Matos Coimbra Virton Rodrigo Targino de Oliveira Vitor Xavier de Lima Vladimir S.Mikryukov Yongzhong Lu Yosuke Matsuda Yumiko Miyamoto Urmas Kõljalg Leho Tedersoo | 2020 | Fungal Diversity2020，，6： | 1 |
| 17 | Physiological features of periodontal regeneration and approaches for periodontal tissue engineering utilizing periodontal ligament cells显示文摘 | Bruno B B Karina G S Marcio Z C | 2007 | J Biosci Bioeng2007，103，1： | 1 |
| 18 | Antibody reactivity to omp31 from Bru- ceUa melitensis in human and animal infections by smooth and rough brucellae显示文摘 | Juliana C Karina P Laura B | 2004 | Infect Immun2004，11，1： | 1 |
| 19 | CD133 identifies perivascular niches in grade II-IV astroeytomas显示文摘 | Karina C Henrik DS Bjarne WK | 2008 | J Neuroonco2008，90，2： | 1 |
| 20 | Estimation of thermal diffusivity of foods using transfer functions显示文摘 | Mariela Y Glavina Karina C Di Scala Roberta Ansorena | 2006 | LWT2006，39，： | 1 |
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