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| 1 | Modulation of Root Signals in Relation to Stomatal Sensitivity to Root-sourced Abscisic Acid in Drought-affected Plants显示文摘到弄干的土壤导致的根信号的有气孔的敏感可以在环境和植物种类之间变化。这是可能的在根信号之中是相互作用和调整的结果。作为一个压力信号, abscisic 酸(骆驼毛的织物) 在根起一个中央作用射击发信号。pH 和水力的信号可以与骆驼毛的织物信号交往并且这样,联合调整有气孔的回答到改变的土壤水地位。pH 本身能被几个因素,在木部的化学组成在之中流修改,包围容器的实时房间起关键作用。除了木部 pH,更多的注意应该对叶 apoplastic pH 的直接调整被给予,因为当没在木部 pH 上有重要效果时,许多化学组成可能强烈修改叶 apoplastic pH。ABA 信号紧张的直接调整可能是更重要的让有气孔的回答的规定玷污比 ABA 信号本身弄干。如果射击弄干的土壤的通讯的一条持续的根在整个植物水平操作,骆驼毛的织物信号被 ABA 分解代谢和先锋的供应也调整到根。更重要地,骆驼毛的织物分解代谢能在 ABA 信号的命运的决心起关键作用并且从而控制采购根的骆驼毛的织物信号的有气孔的行为。 | Huibo Ren Kaifa Wei Wensuo Jia William John Davies Jianhua Zhang | 2007 | Journal of Integrative Plant Biology2007，49，10： | 11 |
| 2 | Understanding the pathophysiology of postpartum psychosis: Challenges and new approaches显示文摘Postpartum psychosis is a severe psychiatric condition which affects 1-2 of every 1000 mothers shortly after childbirth. Whilst there is convincing evidence that the condition is precipitated by a complex combination of biological and environmental factors, as yet the pathophysiological mechanisms remain extremely poorly defined. Here, I critically review approaches that have been, or are being, employed to identify and characterise such mechanisms; I also review a recent animal model approach, and describe a novel biological risk model that it suggests. Clarification of biological risk mechanisms underlying disorder risk should permit the identification of relevant predictive biomarkers which will ensure that 'at risk' subjects receive prompt clinical intervention if required. | William Davies | 2017 | World Journal of Psychiatry2017，7，2： | 4 |
| 3 | An Optical Coherence Tomography-Guided, Variable Dosing Regimen with Intravitreal Ranibizumab (Lucentis) for Neovascular Age-related Macular Degeneration显示文摘 | Anne E. Fung Geeta A. Lalwani Philip J. Rosenfeld Sander R. Dubovy Stephan Michels William J. Feuer Carmen A. Puliafito Janet L. Davis Harry W. Flynn Maria Esquiabro | 2007 | American Journal of Ophthalmology2007，，4： | 3 |
| 4 | Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial显示文摘 | Kris V Kowdley Eric Lawitz Israel Crespo Tarek Hassanein Mitchell N Davis Michael DeMicco David E Bernstein Nezam Afdhal John M Vierling Stuart C Gordon Jane K Anderson Robert H Hyland Hadas Dvory-Sobol Di An Robert G Hindes Efsevia Albanis William T Symo | 2013 | The Lancet2013，，9883： | 3 |
| 5 | On deaf ears, Mycobacterium avium paratuberculosis in pathogenesis Crohn's and other diseases显示文摘The historic suggestion that Mycobacterium avium subsp. paratuberculosis(Map) might be a zoonotic pathogen was based on the apparent similarity of lesions in the intestine of patients with Crohn's disease(CD) with those present in cattle infected with Map, the etiological agent of Johne's disease. Reluctance to fully explore this possibility has been attributed to the difficulty in demonstrating the presence of Map in tissues from patients with CD. Advances in technology have resolved this problem and revealed the presence of Map in a significant proportion of patients with CD and other diseases. The seminal finding from recent investigations, however, is the detection of Map in healthy individuals with no clinical signs of disease. The latter observation indicates all humans are susceptible to infection with Map and lends support to the thesis that Map is zoonotic, with a latent stage of infection similar to tuberculosis, where infection leads to the development of an immune response that controls but does not eliminate the pathogen. This clarifies one of the reasons why it has been so difficult to document that Map is zoonotic and associated with the pathogenesis of CD and other diseases. As discussed in the present review, a better understanding of the immune response to Map is needed to determine how infection is usually kept under immune control during the latent stage of infection and elucidate the triggering events that lead to disease progression in the natural host and pathogenesis of CD and immune related diseases in humans. | William C Davis | 2015 | World Journal of Gastroenterology2015，21，48： | 2 |
| 6 | Do medical students studying in the United Kingdom have an adequate factual knowledge of basic life support?显示文摘BACKGROUND: Healthcare professionals have a duty to maintain basic life support(BLS) skills. This study aims to evaluate medical students' factual knowledge of BLS and the training they receive.METHODS: A cross-sectional, closed-response questionnaire was distributed to the fi rst-and fourth-year students studying at institutions in the United Kingdom. The paper questionnaire sought to quantify respondent's previous BLS training, factual knowledge of the BLS algorithm using five multiple choice questions(MCQs), and valuate their desire for further BLS training. Students received 1 point for each correctly identifi ed answer to the 5 MCQ's.RESULTS: A total of 3,732 complete responses were received from 21 medical schools. Eighty percent(n=2,999) of students completed a BLS course as part of their undergraduate medical studies. There was a signifi cant difference(P<0.001) in the percentage of the fourth-year students selecting the correct answer in all the MCQ's compared to the fi rst-year students except in identifyingthe correct depth of compressions required during CPR(P=0.095). Overall 10.3%(95% CI 9.9% to 10.7%) of respondents correctly identified the answer to 5 MCQ's on BLS: 9% of the first-year students(n=194) and 12% of the fourth-year students(n=190). On an institutional level the proportion of students answering all MCQ's correctly ranged from 2% to 54% at different universities. Eighty-one percent of students(n=3,031) wished for more BLS training in their curriculum.CONCLUSION: Factual knowledge of BLS is poor among medical students in the UK. There is a disparity in standards of knowledge across institutions and respondents indicating that they would like more training. | Robert D.Willmore Damjan Veljanoski Feray Ozdes Bethan Stephens James Mooney Seamus G.Crumley Arpan Doshi Philippa Davies Shreya Badhrinarayanan Emily Day Kristian Tattam April Wilson Nathan Crang Lorna Green Craig A.Mounsey Howell Fu Joseph Williams Michelle S.D'souza Dhanya Sebastian Liam A.Mcgiveron Matthew G.Percy James Cohen Imogen J.John Alice Lethbridge Imogen Watkins Omar Amin Mubasher A.Qamar John Gerrard Hanrahan Emily Cramond-Wong | 2019 | World Journal of Emergency Medicine2019，10，2： | 2 |
| 7 | Visit‐to‐Visit Blood Pressure Variability and Cardiovascular Death in the Systolic Hypertension in the Elderly Program显示文摘 | John B. Kostis Jeanine E. Sedjro Javier Cabrera Nora M. Cosgrove John S. Pantazopoulos William J. Kostis Sara L. Pressel Barry R. Davis | 2014 | J Clin Hypertens2014，，1： | 2 |
| 8 | Impact of metabolic indices on central artery stiffness: independent association of insulin resistance and glucose with aortic pulse wave velocity显示文摘 | D. R. Webb K. Khunti R. Silverman L. J. Gray B. Srinivasan P. S. Lacy B. Williams M. J. Davies | 2010 | Diabetologia2010，，6： | 2 |
| 9 | 2004英国高血压学会高血压治疗指南(BHS-IV):概要显示文摘在高血压领域,不断出现的新证据已日益受到关注。例如:血压可作为心血管疾病的一个危险因素;改进生活方式对于预防和治疗高血压的重要意义;不同类型药物的有效性和安全性;高危高血压患者包括糖尿病患者的治疗;心血管疾病总体危险性评估的重要性以及使用他汀类药物所获得的额外益处。 | Bryan Williams Neil R Poulter Peter S Sever Morris J Brown Mark Davis Gordon T McInnes John F Potter 邱洪 | 2004 | 英国医学杂志中文版2004，7，5： | 2 |
| 10 | Regula- tion of leaf and fruit growth in plants growing in drying soil: ex ploitation of the plants' chemical signalling system and hydraulic architecture to increase the efficiency of water use in agriculture 显示文摘 | William J Davies Mark A Bacon D Stuart Thompson | 2000 | Journal of Experimental Botany2000，51，350： | 1 |
| 11 | Natural history of uterine polyps and leiomyomata显示文摘 | Deborah J DeWaay Craig H Syrop Ingrid E Nygaard William A Davis Bradley J Van Voorhis | 2002 | Obstetrics & Gynecology2002，，1： | 1 |
| 12 | The prevalence, severity, and impact of painful diabetic peripheral neuropathy in type 2 diabetes显示文摘 | Davies M Brophy S Williams R | 2006 | Diabetes Care2006，29，7： | 1 |
| 13 | Regulation of leaf and fruit growth in plants growing in drying soil: exploitation of the plants' chemical signalling system and hydraulic architecture to increase the efficiency of water use in agriculture显示文摘 | WILLIAM J DAVIES | | Journal of Experimental0，，： | 1 |
| 14 | Land-based Activities: What Remains to Be Done显示文摘 | Williams C Davis B | 1995 | Ocean& costal Management1995，29，1： | 1 |
| 15 | Pharma-cokinetics of oral terbinafine in horses and Greyhound dogs显示文摘 | WILLIAMS M M DAVIS E G KUKANICH B | 2011 | J Vet Pharmacol Ther2011，34，3： | 1 |
| 16 | A Variable-dosing Regimen with Intravitreal Ranibizumab for Neovascular Age-related Macular Degeneration: Year 2 of the PrONTO Study显示文摘 | Geeta A. Lalwani Philip J. Rosenfeld Anne E. Fung Sander R. Dubovy Stephen Michels William Feuer Janet L. Davis Harry W. Flynn Maria Esquiabro | 2009 | American Journal of Ophthalmology2009，，1： | 1 |
| 17 | Epitope mapping ofbovine alpha- lactalbumin using a random phage display peptidelibrary显示文摘 | Hunt AC1 Williams SC Davis PJ | 1997 | Biochem Soc Trans1997，25，2： | 1 |
| 18 | Gender differences in lower extremity mechanics during running 显示文摘 | FERBER R DAVIS I M WILLIAMS D S | 2003 | Clin Biom2003，18，： | 1 |
| 19 | Stomatal control by chemical signalling and the exploitation of this mechanism to increase water use efficiency in agriculturre显示文摘 | Davies William J Wilkmson Sally Loveys Brian | 2002 | New phytologist2002，，3： | 1 |
| 20 | A comparative assessment of th strengths of porcelain veneers for incisor teeth dependent on their design characteristics显示文摘 | Hui KK Williams B Davis EH | 1991 | Br Dent J1991，171，2： | 1 |
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