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1Biological conduit small gap sleeve bridging method for peripheral nerve injury: regeneration law of nerve fibers in the conduit显示文摘The clinical effects of 2-mm small gap sleeve bridging of the biological conduit to repair peripheral nerve injury are better than in the traditional epineurium suture, so it is possible to replace the epineurium suture in the treatment of peripheral nerve injury. This study sought to identify the regeneration law of nerve fibers in the biological conduit. A nerve regeneration chamber was constructed in models of sciatic nerve injury using 2-mm small gap sleeve bridging of a biodegradable biological conduit. The results showed that the biological conduit had good histocompatibility. Tissue and cell apoptosis in the conduit apparently lessened, and regenerating nerve fibers were common. The degeneration regeneration law of Schwann cells and axons in the conduit was quite different from that in traditional epineurium suture. During the prime period for nerve fiber regeneration(2–8 weeks), the number of Schwann cells and nerve fibers was higher in both proximal and distal ends, and the effects of the small gap sleeve bridging method were better than those of the traditional epineurium suture. The above results provide an objective and reliable theoretical basis for the clinical application of the biological conduit small gap sleeve bridging method to repair peripheral nerve injury.Pei-xun Zhang Li-ya A Yu-hui Kou Xiao-feng Yin Feng Xue Na Han Tian-bing Wang Bao-guo Jiang 2015Neural Regeneration Research2015,10,1:9
2Biodegradable chitin conduit tubulation combined with bone marrow mesenchymal stem cell transplantation for treatment of spinal cord injury by reducing glial scar and cavity formation显示文摘We examined the restorative effect of modified biodegradable chitin conduits in combination with bone marrow mesenchymal stem cell transplantation after right spinal cord hemisection injury. Immunohistochemical staining revealed that biological conduit sleeve bridging reduced glial scar formation and spinal muscular atrophy after spinal cord hemisection. Bone marrow mesenchymal stem cells survived and proliferated after transplantation in vivo, and differentiated into cells double-positive for S100(Schwann cell marker) and glial fibrillary acidic protein(glial cell marker) at 8 weeks. Retrograde tracing showed that more nerve fibers had grown through the injured spinal cord at 14 weeks after combination therapy than either treatment alone. Our findings indicate that a biological conduit combined with bone marrow mesenchymal stem cell transplantation effectively prevented scar formation and provided a favorable local microenvironment for the proliferation, migration and differentiation of bone marrow mesenchymal stem cells in the spinal cord, thus promoting restoration following spinal cord hemisection injury.Feng Xue Er-jun Wu Pei-xun Zhang Li-ya A Yu-hui Kou Xiao-feng Yin Na Han 2015Neural Regeneration Research2015,10,1:7
3Fluid-structure Interaction Analysis of 3-D Rectangular Tanks by a Variationally Coupled BEM-FEM and Comparison with Test Results显示文摘KOU H M KIM J A PARK Jang-ho 1998Earthquake Engineering And Structural Dynamics1998,27,:1
4Crack propagation and coalescence in brittle materials under compression显示文摘TANG C A KOU S Q 1998Engineering Fracture Mechanics1998,61,34:1
5Numerical modeling of the heterogeneous rock fracture process using various test techniques显示文摘Liu H Y Kou S Q Lindqvist P A Tang C A 2007Rock Mechanics and Rock Engineering2007,40,2:1
6Numerical simulation of the cutting of inhomogeneous rocks显示文摘Kou S Q Lindqvist P A Tang C A 1999Rock Mechanics and Mining Sciences1999,36,5:1
7Cross-correlation of optical micrecavity biosensor response with immobilized enzyme activity显示文摘Lisa A Delouise Peng Meng Kou Benjamin L Miller 2005Anal Chem2005,77,:1
8Highly selective catalyticconversion of phenolic bio-oil to alkanes 显示文摘Zhao C Kou Y Lemonidou A A 2009Angewandte ChemieInternational Edition2009,48,22:1
9Numerical simulation of the rock fragmentation process induced by indenters显示文摘Liu H Y Kou S Q Lindqvist P A 2002Rock Mechanics and Mining Sciences2002,39,4:1
10Risk factors for spinal epidural hematoma after spinal surgery显示文摘Kou J Fischgrund J Biddinger A 2002Spine2002,27,15:1
11Numerical modelling of the heterogeneous rock fracture process using various test techniques显示文摘Liu H Y Kou S Q Lindqvist P A 2007Rock Mechanics and Rock Engineering2007,40,2:1
12Crack propagation and coalescence in brittle materials under compression显示文摘TANG C A KOU S Q 1998Engineering Fracture Mechanics1998,61,3:1
13Oxygen- containing analogues of juvenile hormone III 显示文摘Davies K A Kou K G M Wulff J E 2011Tetrahedron Letters2011,52,18:1
14Canine Population Data Generated fi:om a Multiplex STR Kit for Use in Forensic Casework 显示文摘Kanthaswamy S Ttom BK Mattila A-M Johnston E Dayton M Kinaga J Erickson B J-A Halverson J Fantin D Denise S Kou A Malladi V Satkoski J Budowle B Smith DG Koskinen MT 2009Journal of Forensic Sciences2009,54,4:1
15Numerical simulation of the rock fragmentation process induced by indenters显示文摘Liu H Y Kou S Q Lindqvist P A 2002International Journal of Rock Mechanics and Mining Sciences2002,39,4:1
16Effect of Post-Oxidizing Time on Corrosion Properties of Plasma Nitrocarburized AISI 1020Steel显示文摘Kou Hyun Lee a Ki Suk Nama Pyung Woo Shin 2003Materials Letters2003,57,:1
17Numerical studies on Bit- Rock fragmentation mechanisms 显示文摘Liu H Y Kou S Q Lindqvist P A 2008International Journal of Geomechanics2008,8,1:1
18Determinants of the ventricular rate during atrial frbrillation显示文摘Toivonen L Kadish A Kou W 1990J Am Coll Cardiol1990,16,:1
19Numericalmodeling of the heterogeneous rock fracture processusing various test techniques显示文摘LIU H Y KOU S Q LINDQVIST P A 2007Rock Mechanics andRock Engineering2007,40,2:1
20The draft genome of watermelon (Citrullus lanatus ) and reseqnencing of 20 diverse accessions显示文摘Guo S G Zhang J G Sun H H Salse J Lucas W J Zhang H Y Zheng Y Mao L Y Ren Y WangZ W Min J M Guo X S Murat F Ham B K Zhang Z L Gao S Huang M Xu Y M Zhong S L Bombarely A Mueller L Zhao H He H Q Zhang Y Zhang Z H Huang S W Tan T Pang E Lin K Hu Q Kuang H H Ni P X Wang B Liu J G Kou Q H Hou W J Zou X H Jiang J Gong G Y Klee K Schoof H Huang Y Hu X S Dong S S Liang D Q Wang J Wu K Xia Y Zhao X Zheng Z Q Xing M Liang X M Huang B Q Lv T Wang J Y Yin Y Yi H P Li R Q Wu M Z Levi A Zhang X P Giovannoni J Wang J Li YF Fei Z J Xu Y 2013Nature genetics2013,45,1:1
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