|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Omentum facilitates liver regeneration显示文摘AIM:To investigate the mechanism of liver regeneration induced by fusing the omentum to a small traumatic injury created in the liver. We studied three groups of rats. In one group the rats were omentectomized; in another group the omentum was left in situ and was not activated,and in the third group the omentum was activated by polydextran particles. METHODS:We pre-activated the omentum by injecting polydextran particles and then made a small wedge wound in the rat liver to allow the omentum to fuse to the wound. We monitored the regeneration of the liver by determining the ratio of liver weight/body weight,by histological evaluation (including immune staining for cytokeratin-19,an oval cell marker),and by testing for developmental gene activation using reverse transcription polymerase chain reaction (RT-PCR). RESULTS:There was no liver regeneration in the omentectomized rats,nor was there significant regeneration when the omentum was not activated,even though in this instance the omentum had fusedwith the liver. In contrast,the liver in the rats with the activated omentum expanded to a size 50% greater than the original,and there was histologically an interlying tissue between the wounded liver and the activated omentum in which bile ducts,containing cytokeratin-19 positive oval cells,extended from the wound edge. In this interlying tissue,oval cells were abundant and appeared to proliferate to form new liver tissue. In rats pre-treated with drugs that inhibited hepatocyte growth,liver proliferation was ongoing,indicating that regeneration of the liver was the result of oval cell expansion. CONCLUSION:Activated omentum facilitates liver regeneration following injury by a mechanism that depends largely on oval cell proliferation. | Ashok K Singh Nishit Pancholi Jilpa Patel Natalia O Litbarg Krishnamurthy P Gudehithlu Perianna Sethupathi Mark Kraus George Dunea Jose AL Arruda | 2009 | World Journal of Gastroenterology2009，15，9： | 2 |
| 2 | High concentrations of sVCAM-1 and slCAM-1 in the cerebrospinal fluid of patients with intracerebral haemorrhage are associated with poor outcome显示文摘 | Kraus J Oschmann P Leis S | 2002 | J Neurol Neurosurg Psychiatry2002，73，3： | 1 |
| 3 | Mutual interactions of boar seminal plasma proteins studied by immuno-logical and chromatographic methods显示文摘 | Manaskova P Balinova P Kraus M | 2003 | American Journal of Reproductive Immunology2003，50，5： | 1 |
| 4 | Characteristics and prognosis of myocardial infarction in patients with normal coronary arteries显示文摘 | Ammann P Marschall S Kraus M | 2000 | Chest2000，117，2： | 1 |
| 5 | Intuitive toxicology:Expert and lay judgments of chemical risk显示文摘 | Kraus N Malmfors T Slovic P | 1992 | Risk Analysis1992，12，2： | 1 |
| 6 | The search for the uremic toxin: The case for carbamoylation of amino acids and proteins 显示文摘 | Kraus L M Kraus A P Jr | 1998 | Wien Klin Wochenschr1998，110，15： | 1 |
| 7 | Social class as culture:The convergence of resources and rank in the social realm 显示文摘 | KRAUS M W PIFF P K KELTNER D | 2011 | Current Directions in Psychological Science2011，20，4： | 1 |
| 8 | Two-photon excitation and luminescence of a CaWO4 scintillator显示文摘 | MIKHAILIK V B BAILIFF I K KRAUS H RODNYI P A NINKOVIC J | 2004 | Radiat Measur2004，38，： | 1 |
| 9 | MUC1 mucin and trefoil factor 1 protein expression in renal cell carcinoma:correlation with prognosis显示文摘 | Kraus S Abel P D Nachtmann C | 2002 | Hum Pathol2002，33，1： | 1 |
| 10 | Carbamoylation of amino acids and proteins in uremia显示文摘 | Kraus L M Kraus A P Jr | 2001 | Kidney Int Suppl2001，59，78： | 1 |
| 11 | The excretion of heavy metals by the salt marsh cord grass,Spartina alterniflo- ra ,and Spartina's role in mercury cycling显示文摘 | KRAUS M L WEIS P CROW J | 1986 | Mar Environ Res1986，20，： | 1 |
| 12 | Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb显示文摘 | FENG B JIANG J KRAUS P | 2009 | Nat Cell Biol2009，11，： | 1 |
| 13 | Hydro cortison and eumer necrosis factor in sever community- acquired pneumonia:a randomized controlled study显示文摘 | Marik P Kraus P Sribante J | 1993 | Chest1993，104，2： | 1 |
| 14 | Risk perception of prescription drugs:Reports on a survey in Canada显示文摘 | Slovic P Kraus N | 1991 | Canadian Journal of Public Health1991，18，2： | 1 |
| 15 | Total longshore sediment transport rate in the surf zone: field measurements and em-pirical predictions 显示文摘 | Wang P Kraus N C Davis Jr R A | 1998 | Journal of Coastal Research1998，14，1： | 1 |
| 16 | Modulation of ethylene synthesis in acotyledonous soybean and wheat seedlings显示文摘 | Kraus T E Murr D P Hofstra G | 1992 | Journal of Plant Growth Regulation1992，，11： | 1 |
| 17 | Molecular cloning of cDNAs encoding rat and human mediumchain acyl-CoA dchydrogenase and assignmentof the gene to human chromosome Ⅰ显示文摘 | Matsu bara Y Kraus J P Yang-Feng T L | 1986 | Proc Nat Acad Sci1986，83，： | 1 |
| 18 | Contribution of insulin deficiency and insulin resistance to the development of type 2 diabetes : nature of early stage diabetes 显示文摘 | Gallwitz B Kazda C Kraus P | 2013 | Acta Diabetol2013，50，： | 1 |
| 19 | Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe显示文摘 | Thorson M K Majtan T Kraus J P | 2013 | Angew Chem Int Ed2013，52，17： | 1 |
| 20 | Longshore sediment transport rate measured by short-term impoundment 显示文摘 | Wang P Kraus N C | 1999 | Journal of Waterway Port Coastal and Ocean Engineering1999，125，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员