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78篇 您的检索式：作者名="Kaindl"

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	题名	作者	年代	出处	被引量
1	Binding pathway determines norepinephrine selectivity for the human β_(1)AR over β_(2)AR显示文摘Beta adrenergic receptors(βARs)mediate physiologic responses to the catecholamines epinephrine and norepinephrine released by the sympathetic nervous system.While the hormone epinephrine binds β_(1)AR and β_(2)AR with similar affinity,the smaller neurotransmitter norepinephrine is approximately tenfold selective for the β_(1)AR.To understand the structural basis for this physiologically important selectivity,we solved the crystal structures of the human β_(1)AR bound to an antagonist carazolol and different agonists including norepinephrine,epinephrine and BI-167107.Structural comparison revealed that the catecholamine-binding pockets are identical between β_(1)AR and β_(2)AR,but the extracellular vestibules have different shapes and electrostatic properties.Metadynamics simulations and mutagenesis studies revealed that these differences influence the path norepinephrine takes to the orthosteric pocket and contribute to the different association rates and thus different affinities.	Xinyu Xu Jonas Kaindl Mary J.Clark Harald Hübner Kunio Hirata Roger K.Sunahara Peter Gmeiner Brian K.Kobilka Xiangyu Liu	2021	Cell Research2021，31，5：	2
2	The Sukari gold mine,eastern Desert-Egypt:structural setting,mineralogy and fluid inclusion study显示文摘	Helmy H.M Kaindl R Fritz H Loizenbauer J		0，，：	1
3	Acute ascending motoric paraplegia following intrathecal chemotherapy for treatment of acute lymphoblastic leukemia in children: case reports and review of the literature显示文摘	Roll N Boehm H Kaindl AM	2006	Kiln Padiatr2006，218，6：	1
4	Biomorphic cellular silicon carbide ceramics from wood:I, processing and microstnmture显示文摘	Greil P Lifka T Kaindl A	1998	J Eur Ceram Soe1998，18，14：	1
5	Image quality of a wetlaser printer versus a paper printer for full2 field digital mammograms显示文摘	Schueller G Kaindl E Matzek W K	2006	A JR2006，186，：	1
6	Requirements engineering and technology transfer: obstacles, incentives and improvement agenga 显示文摘	HERMAN KAINDL SJAAK BRINKKEMPER JANIS A	2002	Requirements Eng2002，10，7：	1
7	Brief alteration of NMDA or GABAA receptor-mediated neurotran- smission has long term effects on the developing cerebral cortex显示文摘	Kaindl A M Koppelstaetter A Nebrich G	2008	Mol Cell Proteomics2008，7，12：	1
8	Biomorphic cellular silicon carbide ceramics from wood processing and microstructure显示文摘	Greil P Lifka T Kaindl A	1998	Eur Ceram Soc1998，18，14：	1
9	Activation of mi- croglial N-methyl-D-aspartate receptors triggers inflamma- tion and neuronal cell death in the developing and mature brain显示文摘	Kaindl AM Depos V Peineau S	2012	Ann Neurol2012，72，4：	1
10	Spinal muscular atrophy with respiratory distress type 1 (SMARDI) 显示文摘	Kaindl AM Guenther UP Rudnik-Schoneborn S	2008	J Child Neurol2008，23，：	1
11	The yin and yang ofmicroglia显示文摘	Czeh M Gressens P Kaindl AM	2011	Dev Neurosci2011，33，34：	1
12	Biomorphic cellular silicon carbide ceramics from wood: Ⅰ processing and microstructure显示文摘	GREIL P LIFKA T KAINDL A	1998	J Eur Ceram Soc1998，18，：	1
13	Activation of microglial N- methyl-D-aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain 显示文摘	Kaindl AM Degos V Peineau S	2012	Ann Neurol2012，72，4：	1
14	Erythropoietin protects the developing brain from hyperoxia-induced cell death and proteome changes 显示文摘	KAINDL A M SIFRINGER M KOPPELSTAETTER A	2008	Ann Neurol2008，64，5：	1
15	A semi-quantitative technique for determination of CO2 in cordierite by Raman spectroscopy in thin sections显示文摘	Kaindl R Tropper P Deibl I	2006	European Journal of Mineralogy2006，18，：	1
16	Incidence of septic and throm boembolic related deaths after splenectomy in adults显示文摘	PIMPL W KAINDL H	1989	Br J Surg1989，76，5：	1
17	Biomorphic silicon carbide ceramics from wood Ⅰ and Ⅱ 显示文摘	GREIL P LIFKA T KAINDL A	1998	J Eur Ceram Soe1998，18，14：	1
18	Neuronal death and oxidative stress in the developing brain显示文摘	lkonomidou C Kaindl AM	2011	ARS2011，14，8：	1
19	Biomorphic cellular silicon carbide ceramics from wood:I processing and microstructure显示文摘	Greil P Lifka T Kaindl A	1998	Eur Ceram Soc1998，18，14：	1
20	Antiepileptic drugs and the developing brain显示文摘	Kaindl AM Asimiadou S Manthey D	2006	Cell Mol Life Sci2006，63，4：	1

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