维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

15篇 您的检索式：作者名="Kalkum"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Uhrasensitive detection of botulinum neurotoxins and anthrax lethal factor in biological samples by ALISSA 显示文摘	Bagmmyan K Kalkum M	2011	Methods Mol Biol2011，739，：	1
	2	CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals显示文摘	Jin S Kalkum M Overholtzer M	2003	Genes Dev2003，17，3：	1
	3	E protein silencing by the leukemogenic AML1-ETO fusion protein显示文摘	Zhang J Kalkum M Yamamura S		0，，5688：	1
	4	热价制定过程中需考虑的问题显示文摘	郝斌李萍刘幼农 Bernd Kalkum	2005	供热制冷2005，0，9：	1
	5	Protective effector cells of the recombinant Asp f3 anti-Aspergillosis vaccine显示文摘	Diaz-Arevalo D Ito JI Kalkum M	2012	Front Microbiol2012，3，：	1
	6	Analysis of the mouse proteome (I) Brain proteins: separation by two-di- mensional electrophoresis and identification by mass spec- trometry and genetic variation显示文摘	Gauss C Kalkum M Lowe M	1999	Electrophoresis1999，20，3：	1
	7	Biogenesis of T pili in Agrobacterium tumefaciens requires precise VirB2 propilin cleavage and cyclization显示文摘	Lai EM Eisenbrandt R Kalkum M	2002	J Bacteriol2002，184，：	1
	8	Immunotherapy in irtva- sire fungal infection- focus on invasive aspergillosis显示文摘	Lehmhecher T Kalkum M Champer J	2013	Curt Pharm Des2013，19，20：	1
	9	The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2显示文摘	Zhang J Kalkum M Chait BT	2002	Mol Cell2002，9，3：	1
	10	Ultrasensitive Detection of Botulinum Neurotoxins and Anthrax Lethal Factor in Biological Samples by ALISSA显示文摘	Bagramyan K Kalkum M		0，，：	1
	11	CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals显示文摘	Jin S Kalkum M Overholtzer M	2003	Genes Dev2003，17，3：	1
	12	CIAP1 and the serine protease HTRA2 are involved in a novel p53 dependent apoptosis pathway in mammals显示文摘	Jin S Kalkum M Overholtzer M	2003	Genes Dev2003，17，3：	1
	13	Protective effector ceils of the recombinant asp f3 Anti-Aspergillosis vaccine 显示文摘	Diaz-Arevalo D ho JI Kalkum M	2012	Front Mi- crobiol2012，3，：	1
	14	热价制定应科学可行显示文摘	郝斌李萍刘幼农 Bernd Kalkum	2004	建设科技2004，，8：	0
	15	Comparative effectiveness of medical treatment vs.metabolic surgery for histologically proven non-alcoholic steatohepatitis and fibrosis:a matched network meta-analysis显示文摘Background:Non-alcoholic steatohepatitis(NASH)comprises a major healthcare problem affecting up to 30%of patients with obesity and the associated risk for cardiovascular and liver-related mortality.Several new drugs for NASH-treatment are currently investigated.No study thus far directly compared surgical and non-surgical therapies for NASH.This network meta-analysis compares for the first time the effectiveness of different therapies for NASH using a novel statistical approach.Methods:The study was conducted according to the PRISMA guidelines for network meta-analysis.PubMed,CENTRAL and Web of Science were searched without restriction of time or language using a validated search strategy.Studies investigating therapies for NASH in adults with liver biopsies at baseline and after at least 12 months were selected.Patients with liver cirrhosis were excluded.Risk of bias was assessed with ROB-2 and ROBINS-I-tools.A novel method for population-adjusted indirect comparison to include and compare single-arm trials was applied.Main outcomes were NASH-resolution and improvement of fibrosis.Results:Out of 7,913 studies,twelve randomized non-surgical studies and twelve non-randomized surgical trials were included.NASH-resolution after non-surgical intervention was 29%[95%confidence interval(CI):23-40%]and 79%(95%CI:72-88%)after surgery.The network meta-analysis showed that surgery had a higher chance of NASH-resolution than medication[odds ratio(OR)=2.68;95%CI:1.44-4.97]while drug treatment was superior to placebo(OR=2.24;95%CI:1.55-3.24).Surgery(OR=2.18;95%CI:1.34-3.56)and medication(OR=1.79;95%CI:1.39-2.31)were equally effective to treat fibrosis compared to placebo without difference between them.The results did not change when only new drugs specifically developed for the treatment of NASH were included.Conclusions:Metabolic surgery has a higher effectiveness for NASH-therapy than medical therapy while both were equally effective regarding improvement of fibrosis.Trials directly comparing surgery with medication must be urgently conducted.Patients with NASH should be informed about surgical treatment options.	Adrian T.Billeter Beatrice Reiners Svenja E.Seide Pascal Probst Eva Kalkum Christian Rupp Beat P.Müller-Stich	2022	Hepatobiliary Surgery and Nutrition2022，11，5：	0

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费