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| 1 | Defects in cold- hydrostatically extruded aluminium, iron and nickel-base powder products显示文摘 | Mamalis A G Kandeil A de Malherbe M C | 1980 | Mech Working Technol1980,4,: | 1 |
| 2 | Proteolytic enzymes in embryonated chicken eggs sustain the replication of egg-grown low-pathogenicity avian influenza viruses in cells in the absence of exogenous proteases显示文摘 | Ahmed Kandeil Ola Bagato Hassan Zaraket Jennifer Debeauchamp Scott Krauss Rabeh El-Shesheny Richard J. Webby Mohamed A. Ali Ghazi Kayali | 2014 | Journal of Virological Methods2014,,: | 1 |
| 3 | The effect of protected fat on milk yield and composition,digestibilit y, and some biochemical parameters in low producing cows显示文摘 | El-Hafeez S S Tawfik M A Kandeil A N Sayed | 2002 | Assiut Veterinary Medical Journa2002,46,92: | 1 |
| 4 | A prospective, observational, epidemiological evaluation of the aetiology and antimicrobial susceptibility of acute otitis media in Saudi children younger than 5years of age显示文摘 | Khalid A. Al-Mazrou Atef M. Shibl Walid Kandeil Jean-Yves Pir?on Cinzia Marano | 2014 | Journal of Epidemiology and Global Health2014,,3: | 1 |
| 5 | Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutral- isation assays reveal a high prevalence of antibody in drome- dary camels in Egypt, June 2013 显示文摘 | Perera RA Wang P Gomaa MR E1-Shesheny R Kandeil A Bagato O Siu LY Shehata MM Kayed AS Moatasim Y Li M Pooh LL Guan Y Webby RJ All MA Peiris JS Kayali G | 2013 | Euro Surveill2013,18,20: | 1 |
| 6 | A review of design parameters and machine performance for improved die casting quality 显示文摘 | SHAWKI G S A KANDEIL A Y | 1988 | Journal of Mechanical Working Technology1988,16,3: | 1 |
| 7 | Characterization of the recent outbreak of foot-and-mouth disease virus serotype SAT2 in Egypt 显示文摘 | Kandeil A E1-Shesheny R Kayali G | 2013 | Arch Virol2013,158,3: | 1 |
| 8 | Antibody and T cell responses against wild-type and Omicron SARS-CoV-2 after third-dose BNT162b2 in adolescents显示文摘The high effectiveness of the third dose of BNT162b2 in healthy adolescents against Omicron BA.1 has been reported in some studies,but immune responses conferring this protection are not yet elucidated.In this analysis,our study(NCT04800133)aims to evaluate the humoral and cellular responses against wild-type and Omicron(BA.1,BA.2 and/or BA.5)SARS-CoV-2 before and after a third dose of BNT162b2 in healthy adolescents.At 5 months after 2 doses,S IgG,S IgG Fc receptor-binding,and neutralising antibody responses waned significantly,yet neutralising antibodies remained detectable in all tested adolescents and S IgG avidity increased from 1 month after 2 doses.The antibody responses and S-specific IFN-γ^(+)and IL-2^(+)CD8^(+)T cell responses were significantly boosted in healthy adolescents after a homologous third dose of BNT162b2.Compared to adults,humoral responses for the third dose were non-inferior or superior in adolescents.The S-specific IFN-γ^(+)and IL-2^(+)CD4^(+)and CD8^(+)T cell responses in adolescents and adults were comparable or non-inferior.Interestingly,after 3 doses,adolescents had preserved S IgG,S IgG avidity,S IgG FcγRIIIa-binding,against Omicron BA.2,as well as preserved cellular responses against BA.1 S and moderate neutralisation levels against BA.1,BA.2 and BA.5.Sera from 100 and 96%of adolescents tested at 1 and 5 months after two doses could also neutralise BA.1.Our study found high antibody and T cell responses,including potent cross-variant reactivity,after three doses of BNT162b2 vaccine in adolescents in its current formulation,suggesting that current vaccines can be protective against symptomatic Omicron disease. | Xiaofeng Mu Carolyn A.Cohen Daniel Leung Jaime S.Rosa Duque Samuel M.S.Cheng Yuet Chung Howard H.W.Wong Amos M.T.Lee Wing Yan Li Issan Y.S.Tam Jennifer H.Y.Lam Derek H.L.Lee Sau Man Chan Leo C.H.Tsang Karl C.K.Chan John K.C.Li Leo L.H.Luk Sara Chaothai Kelvin K.H.Kwan Nym Coco Chu Masashi Mori Trushar Jeevan Ahmed Kandeil Richard JWebby Wenwei Tu Sophie A.Valkenburg Malik Peiris Yu Lung Lau | 2023 | Signal Transduction and Targeted Therapy2023,8,1: | 0 |
| 9 | Double-antibody-based nano-biosensing systemfor the onsite monitoring of SARS-CoV-2 variants显示文摘The fast and reliable diagnosis of COVID-19 is the foremost priority for promoting public health interventions.Therefore, double-antibody-based immunobiosensor chips were designed, constructed, and exploited for clinicaldiagnosis. Gold nanoparticles/tungsten oxide/carbon nanotubes (AuNPs/WO3/CNTs) were used as the active workingsensor surface to support the chemical immobilization of a mixture of SARS-CoV-2 antibodies (anti-RBD-S and anti-RBD-S-anti-Llama monoclonal antibodies). The morphology and chemical functionalization of the fabricateddisposable immunochips was characterized using scanning electron microscopy (SEM), Fourier transform infrared(FTIR) spectroscopy, cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). After full assayoptimization, the immunobiosensor showed a high sensitivity to detect SARS-CoV-2-S protein with limits of detectionand quantification of 1.8 and 5.6 pg/mL, respectively. On the other hand, for the SARS-CoV-2 whole virus particleanalysis, the detection and quantification limits were determined to be 5.7 and 17 pg/mL, respectively. The biosensorshowed a highly selective response toward SARS-CoV-2, even in the presence of influenza, nontargeting humancoronaviruses, and Middle East respiratory syndrome coronavirus (MERS-CoV). The immunochips exhibited distinctresponses toward the variants of concern: B.1>C.36.3>Omicron> Delta> Alpha coronavirus variants. For biosensorvalidation, twenty-nine clinical specimens were analyzed, and the impedimetric responses were positively detected fortwo Delta samples, eighteen Omicron samples, and six B.1-type samples in addition to three negative samples.Eventually, the immunobiosensor was fabricated in the form of ready-to-use chips capable of sensitive detection ofvirus variants, especially variants of concern (VOC) and interest, in a specimen within 15 min. The chips providedinstantaneous detection with the direct application of clinical samples and are considered a point-of-care device thatcould be used in public places and hot spots. | Heba A.Hussein Ahmed Kandeil Mokhtar Gomaa Rabeay Y.A.Hassan | 2023 | Microsystems & Nanoengineering2023,9,4: | 0 |