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513篇 您的检索式:作者名="Kandil"
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1Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases显示文摘AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary tumors.METHODS This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.CONCLUSION Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%.ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab 2017World Journal of Gastroenterology2017,23,38:15
2Post-endoscopic retrograde cholangiopancreatography pancreatitis: Risk factors and predictors of severity显示文摘AIM To detect risk factors for post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis(PEP) and investigate the predictors of its severity.METHODS This is a prospective cohort study of all patients who underwent ERCP.Pre-ERCP data,intraoperative data,and post-ERCP data were collected.RESULTS The study population consisted of 996 patients.Their mean age at presentation was 58.42(± 14.72) years,and there were 454 male and 442 female patients.Overall,PEP occurred in 102(10.2%) patients of the study population; eighty(78.4%) cases were of mild to moderate degree,while severe pancreatitis occurred in 22(21.6%) patients.No hospital mortality was reported for any of PEP patients during the study duration.Age less than 35 years(P = 0.001,OR = 0.035),narrower common bile duct(CBD) diameter(P = 0.0001) and increased number of pancreatic cannulations(P = 0.0001) were independent risk factors for the occurrence of PEP.CONCLUSION PEP is the most frequent and devastating complication after ERCP.Age less than 35 years,narrower median CBD diameter and increased number of pancreaticcannulations are independent risk factors for the occurrence of PEP.Patients with these risk factors are candidates for prophylactic and preventive measures against PEP.Ayman El Nakeeb Ehab El Hanafy Tarek Salah Ehab Atef Hosam Hamed Ahmad M Sultan Emad Hamdy Mohamed Said Ahmed A El Geidie Tharwat Kandil Mohamed El Shobari Gamal El Ebidy 2016World Journal of Gastrointestinal Endoscopy2016,8,19:10
3Intraoperative endoscopic retrograde cholangiopancreatography: A useful tool in the hands of the hepatobiliary surgeon显示文摘AIM: To evaluate the efficacy of intraoperative endoscopic retrograde cholangio-pancreatography(ERCP) combined with laparoscopic cholecystectomy(LC) forpatients with gall bladder stones(GS) and common bile duct stones(CBDS).METHODS: Patients treated for GS with CBDS were included. LC and intraoperative transcystic cholangiogram(TCC) were performed in most of the cases. Intraoperative ERCP was done for cases with proven CBDS.RESULTS: Eighty patients who had GS with CBDS were included. LC was successful in all cases. Intraoperative TCC revealed passed CBD stones in 4 cases so intraoperative ERCP was performed only in 76 patients. Intraoperative ERCP showed dilated CBD with stones in 64 cases(84.2%) where removal of stones were successful; passed stones in 6 cases(7.9%); short lower end stricture with small stones present in two cases(2.6%) which were treated by removal of stones with stent insertion; long stricture lower 1/3 CBD in one case(1.3%) which was treated by open hepaticojejunostomy; and one case(1.3%) was proved to be ampullary carcinoma and whipple's operation was scheduled. CONCLUSION: The hepatobiliary surgeon should be trained on ERCP as the third hand to expand his field of therapeutic options.Ayman El Nakeeb Ahmad M Sultan Emad Hamdy Ehab El Hanafy Ehab Atef Tarek Salah Ahmed A El Geidie Tharwat Kandil Mohamed El Shobari Gamal El Ebidy 2015World Journal of Gastroenterology2015,21,2:6
4Celecoxib-induced cholestatic liver failure requiring orthotopic liver transplantation显示文摘Selective cyclooxygenase-2 (COX-2) inhibitors are widely used due to their efficacy and good safety profile. However, recent case reports have described varying degrees of liver injuries associated with the use of COX-2 inhibitors. We report the case of a patient who developed acute cholestatic hepatitis progressing to hepatic failure requiring liver transplantation, following a 3-d course of celecoxib for treatment of generalized muscle aches and pains. The clinical presentation, the laboratory data, as well as the liver histopathology were supportive of the putative diagnosis of drug induced liver injury.Ihab I El Hajj Shahid M Malik Hany R Alwakeel Obaid S Shaikh Eizaburo Sasatomi Hossam M Kandil 2009World Journal of Gastroenterology2009,15,31:4
5Electrophysiological neuromonitoring of the laryngeal nerves in thyroid and parathyroid surgery: A review显示文摘Recurrent laryngeal nerve(RLN) injury is one of the most common complications of thyroid surgery. Injury to the external branch of the superior laryngeal nerve is less obvious and affects the voice variably; however, it can be of great significance to professional voice users. Recent literature has led to an increase in the use of neuromonitoring as an adjunct to visual nerve identification during thyroid surgery. In our review of the literature, we discuss the application, efficacy and safety of neuromonitoring in thyroid surgery. Although intraoperative neuromonitoring(IONM) contributes to the prevention of laryngeal nerves injury, there was no significant difference in the incidence of RLN injury in thyroid surgery when IONM was used compared with visual identification alone. IONM use is recommended in high risk patients; however, there are no clear identification criteria for what constitutes 'high risk'. There is no clear evidence that IONM decreases the risk of laryngeal nerve injury in thyroid surgery. However, continuous IONM provides a promising tool that can prevent imminent nerve traction injury by detecting decreased amplitude combined with increased latency.Ahmed Deniwar Parisha Bhatia Emad Kandil 2015World Journal of Experimental Medicine2015,5,2:3
6Dexamethasone mediates protection against acute pancreatitis via upregulation of pancreatitis-associated proteins显示文摘AIM: To examine the influence of dexamethasone on pancreatitis-associated protein (PAP) gene expression using both in vitro and in vivo models of acute pancreati- tis and to study how PAP gene expression correlates with severity of pancreatitis. METHODS: In vitro, IL-6 stimulated pancreas acinar AR42J cells were cultured with increasing concentrations of dexamethasone and assayed for PAP expression (RT-PCR). In vivo , pancreatitis was induced in rats by retrograde injection of 40 g/L taurocholate into the pancreatic duct. Animals were pretreated with dexamethasone (2 mg/kg) daily or saline for 4 d. Pancreata and serum were harvested after 24 h and gene expression levels of PAPⅠ, Ⅱ and Ⅲ were measured by RT-PCR. Severity of pancreatitis was based on serum amylase, pancreatic wet weight, and histopathological score. RESULTS: In vitro, dexamethasone and IL-6 induced a marked transcription of PAPⅠ, Ⅱ and Ⅲ genes in AR42J cells at 24 h (P < 0.05 for all comparisons). In vivo, pancreas mRNA levels of PAPⅠ, Ⅱ or Ⅲ increased by 2.6-fold, 1.9-fold, and 1.3-fold respectively after dexa- methasone treatment, compared with saline treated ani- mals. Serum amylase levels and edema were significantly lower in the dexamethasone group compared with the saline group. Histopathologic evaluation revealed less inflammation and necrosis in pancreata obtained from dexamethasone treated animals (P < 0.05). CONCLUSION: Dexamethasone significantly decreases the severity of pancreatitis. The protective mechanism ofdexamethasone may be via upregulating PAP gene ex- pression during injury.Emad Kandil Yin-Yao Lin Martin H Bluth Hong Zhang Gabriel Levi Michael E Zenilman 2006World Journal of Gastroenterology2006,12,42:3
7The new 6^(th) edition of the WHO Laboratory Manualfor the Examination and Processing of HumanSemen: is it a step toward better standard operatingprocedure?显示文摘Semen analysis(SA)remains the cornerstone of male infertility evaluation and should ideally be performed by an accredited andrology laboratory or in vitro fertilization(IVF)clinics based on the standards defined by the World Health Organization(WHO)for the Examination and Processing of Human Semen and in accordance with the International Organization for Standardization’s Basic Semen Examination on Specification and Test Methods.Eric Chung Mohamed Arafa Florence Boitrelle Hussein Kandil Ralf Henkel Ramadan Saleh Rupin Shah Paraskevi Vogiatzi Armand Zini Ashok Agarwal 2022Asian Journal of Andrology2022,24,2:2
8Multisystem inflammatory syndrome in pediatric COVID-19 patients:a meta-analysis显示文摘Background We aimed to systematically review the clinical and laboratory features of patients with the multisystem inflam-matory syndrome in pediatrics diagnosed during the COVID-19 pandemic.Data sources A literature search in Web of Science,PubMed,Scopus,and Science Direct was made up to June 29,2020.Results Analysis of 15 articles(318 COVID-19 patients)revealed that although many patients presented with the typical multisystem inflammatory syndrome in pediatrics,Kawasaki-like features as fever(82.4%),polymorphous maculopapular exanthema(63.7%),oral mucosal changes(58.1%),conjunctival injections(56.0%),edematous extremities(40.7%),and cervical lymphadenopathy(28.5%),atypical gastrointestinal(79.4%)and neurocognitive symptoms(31.8%)were also com-mon.They had elevated serum lactic acid dehydrogenase,D-dimer,C-reactive protein,procalcitonin,interleukin-6,troponin I levels,and lymphopenia.Nearly 77.0%developed hypotension,and 68.1%went into shock,while 41.1%had acute kidney injury.Intensive care was needed in 73.7%of cases;13.2%were intubated,and 37.9%required mechanical ventilation.Intravenous immunoglobulins and steroids were given in 87.7%and 56.9%of the patients,respectively,and anticoagulants were utilized in 67.0%.Pediatric patients were discharged after a hospital stay of 6.77 days on average(95%CI 4.93-8.6).Conclusions Recognizing the typical and atypical presentation of the multisystem inflammatory syndrome in pediatric COVID-19 patients has important implications in identifying children at risk.Monitoring cardiac and renal decompensation and early interventions in patients with multisystem inflammatory syndrome is critical to prevent further morbidity.Eman A.Toraih Mohammad H.Hussein Rami M.Elshazli Adam Kline Ruhul Munshi Nasrin Sultana Sharven Taghavi Mary Killackey Juan Duchesne Manal S.Fawzy Emad Kandil 2021World Journal of Pediatrics2021,17,2:2
9Column leaching of lanthanides from Abu Tartur phosphate ore with kinetic study显示文摘The dynamic leaching of lanthanides from a west desert phosphate ore, Egypt (Abu Tartur) by hydrochloric acid, nitric acid and sulfuric acid solutions was investigated in this study as a function of acid concentration, flow rate and the presence of some additives such as boric acid. Also the kinetics of leaching of lanthanides was investigated as a function of temperature. It was found that the leaching process could be described by a shrinking-core model, with activation energy about 5.9, 13.8 and 21.9 kJ/M for leaching by HCl, HNO3 and H2SO4, respectively. Based on the experimental results, an empirical equation related to the rate constant of lanthanides leaching to leaching temperature was established for the purpose of process design.A.T. Kandil M.M. Aly E.M. Moussa A.M. Kamel M.M. Gouda M.N. Kouraim 2010Journal of Rare Earths2010,28,4:2
10Electron beam processed plasticized epoxy coatings for surface protection显示文摘Mervat S. Ibrahim Heba A. Mohamed Nadia G. Kandile Hossam M. Said Issa M. Mohamed 2011Materials Chemistry and Physics2011,,1:2
11Time-cost-quality trade-offanalysis for highway construction显示文摘 Amr Kandil 2005Journal of Construction Engineering and Management2005,131,4:1
12Pseudoatrophoderma colli in a male显示文摘Kanan MW Kandil E 1969Br J Dermatol1969,81,1:1
13Synergistic inhibition of thy- roid cancer by suppressing MAPK/PI3K,/AKT pathways 显示文摘Kandil E Tsumagari K Ma J 2013J Surg Res2013,184,2:1
14Depletion of CD8+cells abolishes the pregnancy protective effect of progesterone substitution with dydrogesterone in mice by altering the Th1/Th2cytokine profile显示文摘Blois SM Joachim R Kandil J 2004J Immunol2004,172,:1
15Diagnosis and management of cellulitis and erysipelas显示文摘Maxwell-Scott H Kandil H 2015Br J Hosp Med(Lond)2015,76,8:1
16Proposed wavelet neuro fuzzy combined system for power quality violations detection and diagnosis 显示文摘EIMITWALLY A FARGHAL S KANDIL M 2001IEE Proc-Gener Transm Distrib2001,48,1:1
17Transoral robotic- assisted thyroideetomy with central neck dissection: preelinical cadaver feasibility study and proposed surgical technique 显示文摘Richmon JD Holsinger FC Kandil E 2011J Robot Surg2011,5,4:1
18Proposed wavelet neuron fuzzycombined system for power quality violation detection and diagnosis显示文摘Elmitwally A Farghal S Kandil M 2001IEEE Proc Gener Transm Distrib2001,148,1:1
19Piezcelctric actuators and sensors location for active control of flexible stnletures显示文摘LELEU S ABOU - KANDIL BONNASSIEUX Y 2001IEEE Transactions on Instrumentation and Measurement2001,50,6:1
20Quantifying Electric Power Quality via Fuzzy Modeling and Analytic Hierarchy Processing显示文摘Farghal S A Kandil M S Elmitwally A 2002IEE Proceedings-Gener Trans and Distrib2002,149,1:1
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