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| 1 | Cryptocurrency trading:a comprehensive survey显示文摘In recent years,the tendency of the number of financial institutions to include crypto-currencies in their portfolios has accelerated.Cryptocurrencies are the first pure digital assets to be included by asset managers.Although they have some commonalities with more traditional assets,they have their own separate nature and their behaviour as an asset is still in the process of being understood.It is therefore important to summarise existing research papers and results on cryptocurrency trading,including available trading platforms,trading signals,trading strategy research and risk management.This paper provides a comprehensive survey of cryptocurrency trading research,by covering 146 research papers on various aspects of cryptocurrency trading(e.g.,cryptocurrency trading systems,bubble and extreme condition,prediction of volatility and return,crypto-assets portfolio construction and crypto-assets,technical trading and others).This paper also analyses datasets,research trends and distribution among research objects(contents/properties)and technologies,concluding with some promising opportunities that remain open in cryptocurrency trading. | Fan Fang Carmine Ventre Michail Basios Leslie Kanthan David Martinez-Rego Fan Wu Lingbo Li | 2022 | Financial Innovation2022，8，1： | 21 |
| 2 | Mixed epithelial endocrine neoplasms of the colon and rectum–An evolution over time:A systematic review显示文摘BACKGROUND Mixed tumors of the colon and rectum,composed of a combination of epithelial and endocrine elements of benign and malignant potential are rare neoplasms.These can occur anywhere in the gastrointestinal tract and are often diagnosed incidentally.Though they have been a well-documented entity in the pancreas,where the exocrine-endocrine mixed tumors have been known for a while,recognition and accurate diagnosis of these tumors in the colon and rectum,to date,remains a challenge.This is further compounded by the different terminologies that have been attributed to these lesions over the years adding to increased confusion and misclassification.Therefore,dedicated literature reviews of these lesions in the colon and rectum are inconsistent and are predominantly limited to case reports and case series of limited case numbers.Though,most of these tumors are high grade and of advanced stage,intermediate and low grade lesions of these mixed tumors are also increasingly been reported.There are no established independent consensus based guidelines for the therapeutic patient management of these unique lesions.AIM To provide a comprehensive targeted literature review of these complex mixed tumors in the colon and rectum that chronicles the evolution over time with summarization of historical perspectives of terminology and to further our understanding regarding their pathogenesis including genomic landscape,clinicoradiological features,pathology,treatment,prognosis,the current status of the management of the primary lesions,their recurrences and metastases.METHODS A comprehensive review of the published English literature was conducted using the search engines PubMed,MEDLINE and GOOGLE scholar.The following search terms[“mixed tumors colon”OR mixed endocrine/neuroendocrine tumor/neoplasm/lesion colon OR adenocarcinoma and endocrine/neuroendocrine tumor colon OR mixed adenocarcinoma and endocrine/neuroendocrine carcinoma colon OR Amphicrine tumors OR Collision tumors]were used.Eligibility criteria were defined and all potential relevant items,including full articles and/or abstracts were independently reviewed,assessed and agreed upon items were selected for in-depth analysis.RESULTS In total 237 full articles/abstracts documents were considered for eligibility of which 45 articles were illegible resulting in a total of 192 articles that were assessed for eligibility of which 139 have been selected for reference in this current review.This seminal manuscript is a one stop article that provides a detailed outlook on the evolution over time with summarization of historical perspectives,nomenclature,clinicoradiological features,pathology,treatment,prognosis and the current status of the management of both the primary lesions,their recurrences and metastases.Gaps in knowledge have also been identified and discussed.An important outcome of this manuscript is the justified proposal for a new,simple,clinically relevant,non-ambiguous terminology for these lesions to be referred to as mixed epithelial endocrine neoplasms(MEENs).CONCLUSION MEEN of the colon and rectum are poorly understood rare entities that encompass an extensive range of heterogeneous tumors with a wide variety of combinations leading to tumors of high,intermediate or low grade malignant potential.This proposed new revised terminology of MEEN will solve the biggest hurdle of confusion and misclassification that plagues these rare unique colorectal neoplasms thus facilitating the future design of multi institutional prospective randomized controlled clinical trials to develop and evaluate newer therapeutic strategies that are recommended for continued improved understanding and personal optimization of clinical management of these unique colorectal neoplasms. | Rani Kanthan Suresh Tharmaradinam Tehmina Asif Shahid Ahmed Selliah C Kanthan | 2020 | World Journal of Gastroenterology2020，26，34： | 5 |
| 3 | Fecal Molecular Markers for Colorectal Cancer Screening显示文摘 | Rani Kanthan Jenna-Lynn Senger Selliah Chandra Kanthan Cesare Hassan | 2011 | Gastroenterology Research and Practice2011，，： | 2 |
| 4 | Chlomethiazole protects the brain in transient for brain ischemia when used up to 4h afterthe insult显示文摘 | Ijaz S Kanthan R | 1995 | Neurosci Lett1995，197，： | 1 |
| 5 | Intracerebral human microdialysis:in vivo study of an acute focal ischemic model of the human brain显示文摘 | Kanthan R Shuaib A Griebel R | 1995 | Stroke1995，26，5： | 1 |
| 6 | Platelet rich plasma(PRP)enhances bone healing in non united critical sized defects:a pre-liminary study involving rabbit models显示文摘 | Kanthan SR Kavitha G Addi S | 2011 | Injury2011，42，8： | 1 |
| 7 | Male versus female breast cancers: A population-based comparative immunohistochemical analysis显示文摘 | MUIR D KANTHAN R KANTHAN S C | 2003 | Arch Pathol Lab Med2003，127，1： | 1 |
| 8 | Recurrent solitary fibrous tumor of the pleura with malignant transformation显示文摘 | KANTHAN R TORKIAN B | 2004 | Arch Pathol Lab Med2004，128，4： | 1 |
| 9 | Increased expression of calcineurin in hmnan colorectal adenocarcinomas显示文摘 | Lakshmikuttyamma A Selvakumar P Kanthan R | 2005 | J Cell Biochem2005，95，4： | 1 |
| 10 | Goblet cell carcinoids of the appendix: immunophenotype and ultrastructural study 显示文摘 | Kanthan R Saxena A Kanthan SC | 2001 | Arch Pathol Lab Med2001，125，3： | 1 |
| 11 | Goblet cell carcinoid of the appendix显示文摘 | Pathhavan P S Kanthan R G | 2005 | World Surg Oncol2005，3，1： | 1 |
| 12 | Novel insights in the natural history of Short QT Syndrome 显示文摘 | Mazzanti A Kanthan A Monteforte N | 2014 | J Am Coll Cardiol2014，63，13： | 1 |
| 13 | Algorithmic aspects for functional partitioning and scheduling in hardware/software co-design显示文摘 | WU Ji-gang SR/KANTHAN T JIAO Tao | 2008 | Design Automation on Embedded Systems2008，12，4： | 1 |
| 14 | Goblet cell careinoids of the appendix: immunophenotype and ultrastruetural study 显示文摘 | Kanthan R Saxena A Kanthan S C | 2001 | Arch Pathol Lab Med2001，125，： | 1 |
| 15 | Increased expression of calcineruin in human colorectal adenocarcinomas显示文摘 | Lakshmikuttyamma A Selvakumar P Kanthan R | 2005 | J Cell Biohem2005，95，4： | 1 |
| 16 | Expr-ession of cell cycle proteins in male breast carcinoma显示文摘 | Rani Kanthan Isabella Fried Theresa Rueckl | 2010 | World J Surg Oncol2010，8，： | 1 |
| 17 | Surgical treatment of complex distal humeral fractures: Functional outcome after internal fixation using precontoured anatomic plates显示文摘 | Kanthan Theivendran Peter J. Duggan Subodh C. Deshmukh | 2010 | Journal of Shoulder and Elbow Surgery2010，，4： | 1 |
| 18 | Pulmonary lymphangiticcarcinomatosis from squamous cell carcinoma of the cervix显示文摘 | Kanthan R Senger JL Diudea D | 2010 | World J Surg Oncol2010，8，： | 1 |
| 19 | Goblet cell carcinoid of the appendix显示文摘 | Pahlavan PS Kanthan R | 2005 | World J Surg Oncol2005，3，： | 1 |
| 20 | Recurrent solitary fibrous tumor of the pleura with malignant transformation显示文摘 | Kanthan R TorkianB | 2004 | Arch Pathol Lab Med2004，128，4： | 1 |
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