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| 1 | 在肝的 G6PT-H6PDH-11HSD1 三个一组和它在新陈代谢的症候群的 pathomechanism 的含意显示文摘 The metabolic syndrome, one of the most common clinical conditions in recent times, represents a combination of cardiometabolic risk determinants, including central obesity, glucose intolerance, insulin resistance, dyslipidemia, non-alcoholic fatty liver disease and hypertension. Prevalence of the metabolic syndrome is rapidly increasing worldwide as a consequence of common overnutrition and consequent obesity. Although a unifying picture of the pathomechanism is still missing, the key role of the pre-receptor glucocorticoid activation has emerged recently. Local glucocorticoid activation is catalyzed by a triad composed of glucose-6-phosphate-transporter, hexose-6-phosphate dehydrogenase and 11β-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum. The elements of this system can be found in various cell types, including adipocytes and hepatocytes. While the contribution of glucocorticoid activation in adipose tissue to the pathomechanism of the metabolic syndrome has been well established, the relative importance of the hepatic process is less understood. This review summarizes the available data on the role of the hepatic triad and its role in the metabolic syndrome, by confronting experimental findings with clinical observations. | Ibolya Czegle Miklós Csala József Mandl Angelo Benedetti István Karádi Gábor Bánhegyi | 2012 | World Journal of Hepatology2012，4，4： | 2 |
| 2 | Two-phase anaerobic digestion of water hyacinth or urban garbage显示文摘 | CHANAKYA H N BORGAON KARS RAJAN M G C | 1992 | Bioresource Technology1992，42，： | 1 |
| 3 | Relativistically correct hole-boring and ion acceleration by circularly polarized laser pulses显示文摘 | A P L Robinson P Gibbon M Zepf S Kar R G Evans C Bellei | 2009 | Plasma Physics and Controlled Fusion2009，，2： | 1 |
| 4 | Combating business crime in Sweden:aperformance audit显示文摘 | RUBER G KAR IN | | 0，，： | 1 |
| 5 | A recombinant en- velope protein vaccine against West Nile virus 显示文摘 | Ledizet M Kar K Foellmer H G | 2005 | Vac- cine2005，23，30： | 1 |
| 6 | Thermoluminescent dosimetry of the select seed 125I interstitial brachytherapy seed显示文摘 | An G Bal D Kar P | | 0，，05： | 1 |
| 7 | The efficacy of nonoperative management in childhood blunt hepatic trauma 显示文摘 | Kar kiner A Temir G Utku M | 2005 | Ulus Travma Derg2005，11，2： | 1 |
| 8 | Neuroendocrine pharmacology of stress显示文摘 | Carrasco G A van de Kar L D | 2003 | European Journal of Pharmacology2003，463，13： | 1 |
| 9 | Grate-firing of bio- mass for heat and power production 显示文摘 | Yin C G Rosendahl L A Kar S K | 2008 | Progress in Ener- gy and Combustion Science2008，34，6： | 1 |
| 10 | A survey of available tools and web servers for analysis of protein-protein inter- actions and interfaces 显示文摘 | Tuncbag N Kar G Keskin O | 2009 | Briefings in bioinformatics2009，10，3： | 1 |
| 11 | GHZ correlation provides secure a- nonymous veto protocol 显示文摘 | RAHAMAN R KAR G | 2015 | Computer Science2015，，10： | 1 |
| 12 | Water use efficiency and crop coefficients of dry season oilseed crops显示文摘 | Kar G Kumar A Martha M | 2007 | Agricultural Water Management2007，87，1： | 1 |
| 13 | Water use efficiency and crop coefficients of dry season oilseed crops 显示文摘 | Kar G Kumar A Martha M | 2007 | Agricultural Water Management2007，87，1： | 1 |
| 14 | Influence of granule size on the flow behaviour of heated rice starch dispersions in excess water显示文摘 | Jacquier J C Kar A Lyng J G | 2006 | Carbohydrate Polymers2006，66，4： | 1 |
| 15 | Effect of method and scheduling of irrigation of water and nitrogen use efficiencies of Okra (Abesculentus)显示文摘 | Home P G Panda R K Kar S | 2002 | Agricultural Water Management2002，55，： | 1 |
| 16 | Intravenous milrinone infusion improves congestive heart failure caused by diastolic dysfunction: a briefcase series显示文摘 | ALBRECHT C A GIESLER G M KAR B | 2005 | Tex Heart Inst J2005，32，2： | 1 |
| 17 | Unique ClinicalCharacteristics of primary hyperparathyroidism in India显示文摘 | Mishra S K Agarwal G Kar D K ei al | 2001 | Br J Surg2001，88，5： | 1 |
| 18 | Neuroendocrine pharmacology of stress 显示文摘 | Carrasco G A Van de Kar L D | 2003 | Eur J Pharmacol2003，463，13： | 1 |
| 19 | Neuroendocrine pharma cology of stress显示文摘 | Carrasco G A Van de Kar L D | 2003 | European Journal of Pharmacology2003，463，13： | 1 |
| 20 | Individualism /collectivism as a moderating factor to the self-image congruity concept 显示文摘 | Litvin S W Kar G H | 2003 | Journal of Vacation Marketing2003，10，1： | 1 |
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