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| 1 | High adiponectin levels fail to protect against the risk of hypertension and,in women,against coronary disease:involvement in autoimmunity?显示文摘AIM:To investigate whether serum adiponectin protects against cardiometabolic risk in a population sample with prevailing metabolic syndrome.METHODS:Middle-aged adults representative of a general population with baseline circulating adiponectin measurements(n=1224)were analyzed prospectively at a mean of 3.8 years’follow-up,using continuous values or sex-specific tertiles.Total adiponectin was assayed by an ELISA kit.Type-2 diabetes was identified by criteria of the American Diabetes Association.Hypertension was defined as a blood pressure≥140 mmHg and/or≥90 mmHg and/or use of antihypertensive medication.Outcomes were predicted using Cox proportional hazards regression analysis in models that were controlled for potential confounders.RESULTS:In models of multiple linear regression,sex hormone-binding globulin,fasting insulin(inverse)and,in men,age were significant independent covariates of serum adiponectin which further tended in women to be positively associated with serum creatinine.Cox regression analyses for incident coronary heart disease(CHD),adjusted for sex,age,non-HDL cholesterol,waist circumference and C-reactive protein,revealed significant inverse association with adiponectin tertiles in men but not women(HR=0.66;95%CI:0.32-1.38 for highest tertile).Cox regression for type-2 diabetes in a similar model(wherein glucose replaced non-HDL cholesterol),adiponectin tertiles appeared to protect in each gender.HR for incident hypertension roughly displayed unity in each of the adiponectin tertiles(P-trend=0.67).CONCLUSION:High adiponectin levels failed to protect against the development of hypertension and,in women,against CHD,presumably paralleling impairment in renal function as well.Involvement of adiponectin in autoimmune complex with loss of antioxidative-antiatherogenic properties may be underlying. | Altan Onat Mesut Aydln Günay Can Bayram Kroglu Ahmet Karagz Servet Altay | 2013 | World Journal of Diabetes2013，4，5： | 3 |
| 2 | 采用耐热乳酸脱氢酶制备生物传感器来检测汞和镍(英文)显示文摘分析了采用耐热细菌LDH酶制备的生物传感器对汞和镍的响应性。将酶纯化、固定在一个涂有PGA-吡咯聚合材料的金箔上作为工作电极,在增加溶液中乳酸浓度的情况下测定生物传感器对两种不同浓度的汞和镍溶液的响应性。当溶液中含25×10-7mmol/L汞和17×10-5mmol/L镍时,生物传感器的电流响应分别从0.32μA下降到0.09μA和从4.13μA下降到2.63μA。在含25×10-7mmol/L汞溶液中,生物传感器的敏感性从0.0102μA/(mmol·L-1)下降到0.0043μA/(mmol·L-1)。另一方面,镍的存在并没有导致传感器敏感性的降低。结果表明,制备的生物传感器适合用于含汞和镍溶液中的汞检测。 | brahim TAN Elif ERHAN Pinar KARAGZ Melek ZKAN | 2011 | Transactions of Nonferrous Metals Society of China2011，21，10： | 3 |
| 3 | Attributes of cancer patients admitted to the emergency department in one year显示文摘BACKGROUND: Cancer patients frequently visit the emergency department(ED) with various symptoms of cancer. The purpose of this study was to determine the clinical characteristics and 1-year survival rate of cancer patients in the ED of a university hospital.METHODS: We conducted a retrospective review of 408 cancer patients who visited the ED between January 2011 and December 2011. Patient information on demographics, chief complaints, fi ndings, and survival was gathered from the hospital registry and corresponding health administration.RESULTS: The study included 240(58.8%) males and 168(41.2%) females with a median age of 57.9 years(range 19–87). Regarding cancer staging, 266 patients(65.3%) had metastatic disease and 142(34.7%) had local and loco-regional disease. The hospitalization rate was 59.6%. The most common symptoms were shortness of breath(23.2%), pain(17.8%), fever(14.2%), and nausea/vomiting(14.4%). The most common cancer sites were the lung(32.5%), gastrointestinal system(25.4%), and breast(9.3%). The initial evaluation determined progressive disease(42.4%), chemotherapy effects(20.7%), infections(17.2%), radiotherapy effects(4.7%), extravasation(1.8%), anemia(1.4%), and unknown(11.3%). During follow up, 191(46.8%) patients died after admission to the ED. The 1-year overall survival of all patients was 7.3 months.CONCLUSIONS: Symptom management in cancer patients is a complex multifaceted concern for the emergency physician. Because of the increasing prevalence of cancer patients, emergency physicians should develop consensus algorithms in collaboration with the relevant disciplines to manage the commonly encountered problems. | Muallaoglu Sadik Karagün Ozlem Mertsoylu Huseyin Besen AliAyberk Sezer Ahmet Ozyilkan Ozgur | 2014 | World Journal of Emergency Medicine2014，5，2： | 3 |
| 4 | Analysis of active vibration control in smart structures by ANSYS显示文摘 | KARAG(U)LLE H MALGACA L (O)KTERN H F | 2004 | Smart Materials and Structure2004，13，： | 1 |
| 5 | Traumaticpneumorrhachis : etiology, pathomechanism, diagnosis, andtreatment显示文摘 | Gelalis ID Karage'orgos A Amaoutoglou C | 2011 | Spine J2011，11，2： | 1 |
| 6 | Antioxidant activity and proline content of leaf extracts from Dorystoechas hastata显示文摘 | Karagzler A A Erda gB Emek Y C Uygun D A | 2008 | Food Chemistry2008，111，2： | 1 |
| 7 | Preparation and characterization of activated carbon from waste biomass 显示文摘 | TURGAY TAY SUAT UCARB SELHAN KARAG | 2009 | Journal of Hazardous Materials2009，165，： | 1 |
| 8 | Prewarmming:Preventing intraoperative hypothemermia显示文摘 | Kiekkas P Karag M | 2005 | British Journal of Perioperative Nursing2005，15，10： | 1 |
| 9 | The efficacy of amiodarone- propranolol combination for the management of childhood ar-rhythmias 显示文摘 | Akin A Karag Z T Aykan HH | 2013 | Pacing and Clinical Electrophysiology2013，36，6： | 1 |
| 10 | Preparation and characterization of activated carbon from waste biomass显示文摘 | Taya T Ucarb S Karagz S | 2009 | Journal of Hazardous Materials2009，165，： | 1 |
| 11 | Antioxidant activity and proline content of leaf extracts from dorystoechas hastate 显示文摘 | Arife Alev Karag?zler | 2008 | Food Chemistry2008，111，： | 1 |
| 12 | Herstellung von schnell-ar beitsstahl durch einbringen von NbC-Puiver in eine matrixsehmelze显示文摘 | L(o)cker K D Karag(o)z S Jeglitsch F | 1988 | Berg-und H(u)ttenm(a)nnische Monatshefte1988，133，： | 1 |
| 13 | Nasolacrimal system:evaluation with gadolinium-enhanced MR dacryocystography with a threedimensional fast spoiled gradient-recalled technique显示文摘 | Karagülle T Erden A Erden I | | 0，，09： | 1 |
| 14 | Simulation and analysis of vibration signals generated by rolling element bearing with defects显示文摘 | Zeki Kiral Hira Karagülle | 2003 | Tribology International2003，，9： | 1 |
| 15 | Effect of electrolyte on surface free energy components of feldspar minerals using thin-layer wicking method显示文摘 | C. Karagüzel M.F. Can E. S?nmez M.S. ?elik | 2004 | Journal of Colloid And Interface Science2004，，1： | 1 |
| 16 | Amulticenter study of the antimicrobial of Macmiror and Macmiror Complex in the treatment of vaginal infections 显示文摘 | | 1999 | Akush Ginekol ( sofiia )1999，，3： | 1 |
| 17 | Rheological properties of reduced-fat and low-fat ice cream containing whey protein isolate and inulin显示文摘 | Ay?e Sibel Akal?n Cem Karag?zlü Gülfem ünal | | European Food Research and Technology0，，： | 1 |
| 18 | Determination of carbide and matrix compositions in high-speed steels by analytical electron microscopy显示文摘 | S. Karag?z I. Liem E. Bischoff H. F. Fischmeister | 1989 | Metallurgical Transactions A1989，，12： | 1 |
| 19 | Activated carbons from waste biomass by sulfuric acid activation and their use on methylene blue adsorption显示文摘 | Karag S Tay T Ucar S | 2008 | Bioresource Technology2008，99，14： | 1 |
| 20 | Evaluation of the effects of radiotherapy to the chiasm and optic nerve by visual psychophysical and electrophysiologic tests in nasopharyngeal carcinoma显示文摘 | EsassolakM Karag(o)z U Yalman D | | 0，，04： | 1 |
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