|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Serum cytokine profile in patients with hepatitis B e antigen-negative chronic active hepatitis B and inactive hepatitis B virus carriers显示文摘An insufficient cellular immune response seems to be critical for the immunopathogenesis of chronic hepatitis B virus infection.We have previously demonstrated no differences of T-lymphocyte subsets in blood between inactive hepatitis B s antigen(HBsAg) carriers and patients with HBeAg-negative chronic active hepatitis B.This study investigated the peripheral blood cytokine profile in patients with HBeAg-negative chronic active hepatitis B infection(Group A,n = 21) and inactive HBsAg carriers(Group B,n = 13).Serum cytokines [interferon(IFN)-γ,tumor necrosis factor-α,interleukin(IL)-1b,IL-4,IL-12,IL-10,IL-2,IL-5,IL-8] were analyzed by using flow cytometry.Patients with chronic active disease presented with significantly decreased levels of IFN-γ and IL-10 compared to inac-tive carriers(P = 0.048 and P = 0.008,respectively).In HBeAg-negative chronic active hepatitis B patients,a significant negative correlation of IFN-γ levels with serum hepatitis B viral load was noted(P = 0.021).In conclusion,patients with HBeAg-negative chronic active hepatitis B and HBsAg inactive carriers display a different cytokine profile.Decreased Th1 response observed in patients with chronic active hepatitis B could be implicated in the persistence of virus replication and ongoing progression of liver disease. | Dimitra Dimitropoulou Marina Karakantza Georgios L Theodorou Lydia Leonidou Stelios F Assimakopoulos Athanasia Mouzaki Charalambos A Gogos | 2013 | World Journal of Gastrointestinal Pathophysiology2013，4，1： | 13 |
| 2 | Thl and Th2 cytokines in a patient with Evans' syndrome and profound lymphopenia 显示文摘 | Karakantza M Mouzaki A Theodoropoulou M | 2000 | B r J Haematol2000，110，4： | 1 |
| 3 | In vivo platelet activation in ischemic stroke patients显示文摘 | Karakantza M Maniatis A Metallinos CI | 2003 | Stroke2003，34，10： | 1 |
| 4 | Cytokine production and monocyle HLA-DR expression as predictors of outcome for patients with community-acquired severe infections显示文摘 | Lekkou A Karakantza M Mouzaki A | 2004 | Clin Diagn Lab Imumunol2004，11，1： | 1 |
| 5 | Cytokine production and monocyte HLADR expression as predictors of outcome for patients with communityacquired severe infections 显示文摘 | Lekkou A Karakantza M Mouzaki A | 2004 | Clin Diagn Lab Immunol2004，11，： | 1 |
| 6 | Clini cal relevance of balance between type 1 and type 2 immune re sponses o{ lymphocyte subpopulations in aplastic anaemia pa tients显示文摘 | Giannakoulas NC Karakantza M Theodorou GL | 2004 | Br J Haematol2004，124，： | 1 |
| 7 | Cytokine production and monocyte HLA-DR expression as predictors of outcome for patients with community-acquired severe infections显示文摘 | Lekkou A Karakantza M Mouzaki A | 2004 | Clin Diagn Lab Immunol2004，11，1： | 1 |
| 8 | In vivo platelet activation in ischemic stroke patients 显示文摘 | Karakantza M Maniatis A Metallinos CI | 2003 | Stroke2003，34，10： | 1 |
| 9 | Cytokine production and monocyte HLA-DR expression as predictors of outcome for patients with community-acquired severe infections显示文摘 | Lekkou A Karakantza M Mouzaki A | 2004 | Clin Diagn Lab Immunol2004，11，1： | 1 |
| 10 | Cytokine production and monocyte HLA-DR expression as predictors of outcome for patients with community-acquired severe infections显示文摘 | Lekkou A Karakantza M Mouzaki A | 2004 | Clin Diagn Lab Immunol2004，11，1： | 1 |
| 11 | Cytokine production and monocyte HLA-DR expression as predictors of outcome for patients with community-acquired severe infections显示文摘 | Lekkou A Karakantza M Mouzaki A | | 0，，： | 1 |
| 12 | Type 1 and type 2 cytokine-producing CD4 + and CD8 + T cells in primary antiphospholipid syndrome显示文摘 | Karakantza M Theodorou GL Meimaris N | 2004 | Ann Hematol2004，83，11： | 1 |
| 13 | A case of severe ADAMTS13 deficiency presenting as thrombotic thrombocytopenic purpura in pregnancy 显示文摘 | Nikolaou M Karakantza M Adonakis G | 2012 | Med Pregl2012，，910： | 1 |
| 14 | Cytokine production and monocyte HLA-DR expression as predictors of outcome for patients with community-acquired severe infections 显示文摘 | Lekkou A Karakantza M Mouzaki A | 2004 | Clin Diagn Lab Immunol2004，11，： | 1 |
| 15 | Clinical relevance of balance between type 1 and type 2 immune responses of lymphocyte subpopulations in aplastic anaemia patients 显示文摘 | Giannakoulas NC Karakantza M Theodorou GL | 2004 | Br J Haematol2004，124，1： | 1 |
| 16 | Cytokine production and monocyte HLA-DR expression as predictors of out- come for patients with community-acqui- red severe infections显示文摘 | Lekkou A Karakantza M Mouzaki A | 2004 | Clin Diagn Lab Imumunol2004，11，1： | 1 |
| 17 | In vivo platelet activation in ischemic stroke patients 显示文摘 | Karakantza M Maniatis A Metallinos CI | 2003 | Stroke2003，34，10： | 1 |
| 18 | Influence of blood transfusions and preoperative anemia on long-term survival in patients operated for non-small cell lung cancer显示文摘 | Panagopoulos ND Karakantza M Koletsis E | | 0，，02： | 1 |
| 19 | Clinical relevance of balance between type 1 and type 2 immune responses of lymphocyte subpopulations in aplastic anaemia patients 显示文摘 | Giannakoulas N C Karakantza M Theodorou G L | 2004 | Br J Haematol2004，124，1： | 1 |
| 20 | Th1 and Th2cytokines in patient with Evans'syndrome and pro-found lymphopenia显示文摘 | Karakantza M Mouzaki A Theodoropoulou M | 2000 | Br Haematol2000，110，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员