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| 1 | Lipoma within inverted Meckel’s diverticulum as a cause of recurrent partial intestinal obstruction and hemorrhage: A case report and review of literature显示文摘Lipoma within an inverted Meckel's diverticulum presen- ting with hemorrhage and partial intestinal obstruction is an exceptional clinical entity. We report a case of 47-year-old male with a history of recurrent episodes of partial intestinal obstruction and melena due to a subserosal lipoma located in the base of an inverted Meckel's diverticulum. According to our knowledge, this is the first case of a lipoma within a Meckel's diverticulum giving rise to this clinical scenario without the existence of heterotrophic gastric or pancreatic tissues. | Güldeniz Karadeniz Cakmak Ali Ugur Emre Oge Tascilar Sibel Bekta■ Bulent Hamdi Uan Oktay Irkorucu Kemal Karakaya Yucel Ustundag Mustafa Comert | 2007 | World Journal of Gastroenterology2007，13，7： | 11 |
| 2 | Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer显示文摘AIM: To evaluate how Helicobacter pylori(H. pylori) is able to evade the immune response and whether it enhances systemic immune tolerance against colorectal cancer.METHODS: This prospective randomized study involved 97 consecutive colorectal cancer patients and 108 cancer-free patients with extra-digestive diseases. Colorectal cancer and cancer-free patients were assigned into subgroups according to H. pylori Ig G seropositivity. Exposure to H. pylori was determined by Ig G seropositivity which was detected by enzyme linked immunoassay(ELISA). Serum neopterin levels were measured by ELISA. Serum tryptophan, kynurenine, and urinary biopterin concentrations were measured by high performance liquid chromatography. Serum nitrite levels were detected spectrophotometrically. Serum indoleamine 2,3-dioxygenase activity was estimated by the kynurenine to tryptophan ratio and by assessing the correlation between serum neopterin concentrations and the kynurenine to tryptophan ratio. The frequencies of increased serum kynurenine to tryptophan ratio of H. pylori seronegative and seropositive colorectal cancer subgroups were estimated by comparing them with the average kynurenine to tryptophan ratio of H. pylori seronegative tumor-free patients.RESULTS: Compared with respective controls, in both H. pylori seronegative and seropositive colorectal cancer patients, while serum tryptophan levels were decreased(controls vs patients; seronegative: 20.37 ± 0.89 μmol/L vs 15.71 ± 1.16 μmol/L, P < 0.05; seropositive: 20.71 ± 0.81 μmol/L vs 14.97 ± 0.79 μmol/L, P < 0.01) the kynurenine to tryptophan ratio was significantly increased(controls vs patients; seronegative: 52.85± 11.85 μmol/mmol vs 78.91 ± 8.68 μmol/mmol, P < 0.01, seropositive: 47.31 ± 5.93 μmol/mmol vs 109.65 ± 11.50 μmol/mmol, P < 0.01). Neopterin concentrations in cancer patients were significantly elevated compared with controls(P < 0.05). There was a significant correlation between serum neopterin levels and kynurenine/tryptophan in control and colorectal cancer patients groups(r s = 0.494, P = 0.0001 and r s= 0.293, P = 0.004, respectively). Serum nitrite levels of H. pylori seropositive cancer cases were significantly decreased compared with seropositive controls(controls vs patients; 26.04 ± 2.39 μmol/L vs 20.41 ± 1.48 μmol/L, P < 0.05) The decrease in the nitrite levels of H. pylori seropositive cancer patients may be attributed to excessive formation of peroxynitrite and other reactive nitrogen species.CONCLUSION: A significantly high kynurenine/tryptophan suggested that H. pylori may support the immune tolerance leading to cancer development, even without an apparent upper gastrointestinal tract disease. | Ayse Basak Engin Bensu Karahalil Ali Esat Karakaya Atilla Engin | 2015 | World Journal of Gastroenterology2015，21，12： | 11 |
| 3 | Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats显示文摘AIM: To evaluate the role of reactive oxygen species in the pathogenesis of acute ethanol-induced gastric mucosal lesions and the effect of Nigella sativa L oil (NS) and its constituent thymoquinone (TQ) in an experimental model.METHODS: Male Wistar albino rats were assigned into 4groups. Control group was given physiologic saline orally (10 mL/kg body weight) as the vehicle (gavage); ethanol group was administrated 1 mL (per rat) absolute alcohol by gavage; the third and fourth groups were given NS (10 mL/kg body weight) and TQ (10 mg/kg body weight p.o) respectively 1 h prior to alcohol intake. One hour after ethanol administration, stomach tissues were excised for macroscopic examination and biochemical analysis.RESULTS: NS and TQ could protect gastric mucosa against the injurious effect of absolute alcohol and promote ulcer healing as evidenced from the ulcer index (UI) values. NS prevented alcohol-induced increase in thiobarbituric acid-reactive substances (TBARS), an index of lipid peroxidation. NS also increased gastric glutathione content (GSH), enzymatic activities of gastric superoxide dismutase (SOD) and glutathione-S-transferase (GST). Likewise, TQ protected against the ulcerating effect of alcohol and mitigated most of the biochemical adverse effects induced by alcohol in gastric mucosa, but to a lesser extent than NS. Neither NS nor TQ affected catalase activity in gastric tissue.CONCLUSION: Both NS and TQ, particularly NS can partly protect gastric mucosa from acute alcohol-induced mucosal injury, and these gastroprotective effects might be induced, at least partly by their radical scavenging activity. | Mehmet Kanter Halit Demir Cengiz Karakaya Hanefi Ozbek | 2005 | World Journal of Gastroenterology2005，11，42： | 9 |
| 4 | Electronic Nose and Its Applications: A Survey显示文摘In the last two decades,improvements in materials,sensors and machine learning technologies have led to a rapid extension of electronic nose(EN)related research topics with diverse applications.The food and beverage industry,agriculture and forestry,medicine and health-care,indoor and outdoor monitoring,military and civilian security systems are the leading fields which take great advantage from the rapidity,stability,portability and compactness of ENs.Although the EN technology provides numerous benefits,further enhancements in both hardware and software components are necessary for utilizing ENs in practice.This paper provides an extensive survey of the EN technology and its wide range of application fields,through a comprehensive analysis of algorithms proposed in the literature,while exploiting related domains with possible future suggestions for this research topic. | Diclehan Karakaya Oguzhan Ulucan Mehmet Turkan | 2020 | International Journal of Automation and computing2020，17，2： | 9 |
| 5 | Protective effects of erythropoietin against acute lung injury in a rat model of acute necrotizing pancreatitis显示文摘瞄准:为了调查外长的 erythro-poietin (EPO ) 的效果,在钠 taurodeoxycholate- 的一个试验性的模型的尖锐的肺损害(ALI ) 上的管理导致了尖锐引起坏死胰腺炎(ANP ) 。方法:47 只男 Wistar 白鼠随机被划分成 7 个组:假冒的组(n = 5 ) , 3 个 ANP 组(n = 7 各个) 并且 3 个 EPO 组(n = 7 各个) 。ANP 被导致由后退进胆总管的 5% 钠 taurodeoxycholate 的注入。在 EPO 组的老鼠收到了 1000 U/kg 肌内的 EPO 立即在 ANP 的正式就职以后。在 ANP 组的老鼠相反被给 1 mL 生理盐水。所有动物被牺牲在手术后 24 h, 48 h 和 72 h。浆液 amilase, IL-2, IL-6 和肺织物 malondialdehyde (MDA ) 被测量。胸膜渗漏体积和肺 / 身体重量(LW/BW ) 比率是计算的。TNF-alpha, IL-2 和 IL-6 的织物层次组织化学地是屏蔽免疫。另外, ox-LDL 累积与免疫者荧光灯的染色被估计。在肺的组织病理学说的改变也被获得。结果:吝啬的胸膜渗漏体积,计算 LW/BW 比率,浆液 IL-6 和肺织物 MDA 层次比在 ANP 组在 EPO 组是显著地更低的。不,统计上,有效差量在这些组之中在浆液或 IL-2 的织物价值被观察。当时, ox-LDL 的肿瘤坏死 factor-alpha (TNF-alpha ) 和 IL-6 和累积的水平在 ANP 组的肺纸巾是明显的与 EPO 组相比,特别地在 72 h。组织病理学说的评估在外长的 EPO 管理以后在肺损害参数证实了改进,特别地在 48 h 和 72 h。结论:EPO 管理由禁止 polymorphonuclear (PMNL ) 在 ALI 参数导致重要减少累积,减少专业版的层次在每氧化的循环,保存微脉管的内皮房间正直和减少的氧化联系压力的类脂化合物的煽动性的 cytokines 并且因此,能在导致 ANP 的 ALI 被认为是一个 cytoprotective 代理人。 | Oge Tascilar Güldeniz Karadeniz Cakmak Ishak Ozel Tekin Ali Ugur Emre Bulent Hamdi Ucan Burak Bahadir Serefden Acikgoz Oktay Irkorucu Kemal Karakaya Hakan Balbaloglu Gürkan Kertis Handan Ankarali Mustafa Comert | 2007 | World Journal of Gastroenterology2007，13，46： | 8 |
| 6 | Use of Natural Antioxidants in Meat and Meat Products显示文摘 | M. Karakaya E. Bayrak K. Ulusoy | 2011 | Journal of Food Science and Engineering2011，1，1： | 8 |
| 7 | Appendiceal mucocele: Case reports and review of current literature显示文摘The mucocele of the appendix is an uncommon disorder which is often asymptomatic but sometimes causes acute appendicitis-like symptoms. Sometimes, patients with mucocele can present with confusing symptoms. Preoperative suspicion and diagnosis of appendiceal mucocele are important. Ultrasonography and computed tomography are useful tools for the diagnosis of appendiceal mucocele. It may be also recognised by colonoscopy as a smooth submucosal lesion of the cecum. Optima management of the mucocele could be achieved through accurate preoperative diagnosis. Preoperative diagnosis is a major component for minimizing intra-operative and post-operative complications. We herein report five cases and discuss the diagnostic methods and surgical treatment. | Kemal Karakaya Figen Barut Ali Ugur Emre Hamdi Bulent Ucan Guldeniz Karadeniz Cakmak Oktay Irkorucu Oge Tascilar Yucel Ustundag Mustafa Comert | 2008 | World Journal of Gastroenterology2008，14，14： | 8 |
| 8 | 不同单色光照饲养条件下肉鸡生长性能和肉品质特性的研究显示文摘试验选用480只罗斯母肉仔鸡,研究其在不同单色光照饲养条件下腿肌和胸肌的品质特性。鸡孵化后,随机分为3个光照组,对照组:微型白炽灯光照;G-B光照组:先由绿色单色光照3周,后为蓝色单色光照3周;G-GB混合光照组:先由绿色单色光照3周,后为蓝色单色光+绿色单色光照3周。试验结果表明,G-B光照组和G-GB混合光照组肉鸡的耗料量、体重和总肌重显著高于对照组;与G-B光照组和G-GB混合光照组相比,对照组肉鸡的胸肌和腿肌有较低的pH和持水性能,但是有较高滴水损失;与其他两组相比,G-GB混合光照组肉鸡的肌肉组织更为松软。本试验证明了G-B光照和G-GB混合光照的饲养条件可以改善母肉鸡肌体和肌肉的生长性能及其肉品质特性。 | Karakaya M ParlatS S Yilmaz M T Yildirim I Ozalp B | 2009 | 饲料博览2009，，7： | 3 |
| 9 | Contrast-enhanced coronary artery visualization by dual-source computed tomography—Initial experience显示文摘 | Stephan Achenbach Dieter Ropers Axel Kuettner Thomas Flohr Bernd Ohnesorge Herbert Bruder Heike Theessen Meri Karakaya Werner G. Daniel Werner Bautz Willi A. Kalender Katharina Anders | 2005 | European Journal of Radiology2005，，3： | 3 |
| 10 | Clinical risk factors for the development of consecutive exotropia:a comparative clinical study显示文摘AIM: To compare a group of patients with consecutive exotropia with patients who had ≤10 prism diopters(PD)esotropia or no deviation postoperatively in terms of probable clinical risk factors for the development of consecutive exotropia.METHODS: The study recruited fourteen patients who developed consecutive exodeviation during follow-up period after the correction of esotropia who were categorized as group 1 and thirty-one patients who had still ≤10 PD esotropia or no deviation at the final visit that were considered as group 2. Clinical risk factors leading the development of consecutive deviation were analyzed as the main outcome measures.RESULTS: The mean age of patients was 4.57±3.11 y in group 1 and 5.10±3.52 y in group 2(P =0.634). There was no significant difference of preoperative near and distant deviations among two groups(P =0.835, 0.928respectively). The mean amount of medial rectus recession and lateral rectus resection was similar in both groups(P =0.412, 0.648 respectively). Convergence insufficiency and neurological diseases were more frequent in group 1(P =0.007, 0.045). Accompanying neurological disease was found to be as a significant factor increasing the risk of the development of consecutive exotropia significantly [odds ratios(OR):5.75(1.04-31.93)]. CONCLUSION: Accompanying neurological disease appears to be a significant clinical risk factor for the development of consecutive exodeviation during postoperative follow-up after the correction of esotropia.However, larger studies are needed in order to interpret the results to the clinical practice and to ascertain other concurrent risk factors. | Hande Tayla Sekeroglu Kadriye Erkan Turan Jale Karakaya Emin Cumhur Sener Ali Sefik Sanac | 2016 | International Journal of Ophthalmology(English edition)2016，9，6： | 2 |
| 11 | Spontaneous rupture of a hepatic hydatid cyst into the peritoneum causing only mild abdominal pain:A case report显示文摘Hydatid disease is an endemic disease in certain areas of the world. It is located mostly in the liver. Spontaneous rupture of the hydatid cyst into the peritoneum is a rare condition, which is accompanied by serious morbidity and mortality generally. We present herein a case with a spontaneous rupture of a hepatic hidatid disease into the peritoneum without any serious symptoms. A 15-year-old boy was admitted to the emergency room with a mild abdominal pain lasting for a day. Physical examination revealed only mild abdominal tenderness. There was no history of trauma or complaints related to hydatid diseases. Ultrasonography showed a large amount of free fluid and a cystic lesion with irregular borders in the liver. He was operated on. Postoperative albendazol therapy was given for 2 mo. No recurrence or secondary hydatidosis was seen on CT investigation in the 3rd, 6th and 12th mo following surgery. | Kemal Karakaya | 2007 | World Journal of Gastroenterology2007，13，5： | 2 |
| 12 | Pharmacological Treatment of Mild Cognitive Impairment as a Prodromal Syndrome of Alzheimer’s Disease显示文摘 | Tarik Karakaya Fabian Fu?er Johannes Schroder Johannes Pantel | 2013 | Current Neuropharmacology2013，，1： | 1 |
| 13 | Effects of heat treatment and in vitro digestion on the Angiotensin converting enzyme inhibitory activity of some legume species显示文摘 | H Gül Akllhoglu Sibel Karakaya | | 0，，： | 1 |
| 14 | Is decline in serum albumin an ominous sign for subsequent peritonitis in peritoneal dialysis patients?显示文摘 | Ozturk S Soyluk O Karakaya D | 2009 | Adv Perit Dial2009，25，： | 1 |
| 15 | Analysis of the Istanbul Forensic Medicine Institute expert decisions on recurrent laryngeal nerve injuries due to thyroidectomy between2008-2012显示文摘 | Karakaya MA Koc O Ekiz F | 2016 | Ulusal cerrahi dergisi2016，32，1： | 1 |
| 16 | Anaphylactic Reaction to Drugs Commonly Used for Gastrointestinal System Diseas:3 Case Reports and Review of the Literature 显示文摘 | Demirkan K Bozkurt B Karakaya G | 2006 | J lnvestig AUergol Clin Immunol2006，16，3： | 1 |
| 17 | Serum paraoxonese activity and phenotype distribution in Turkish subjects with coronary heart disease and its relationship to serum lipids and lipoproteins显示文摘 | Karakaya A Ibis S Kural T | 1999 | Chem Biol Interact1999，118，： | 1 |
| 18 | Molybdenum cofactor deficiency: review of 12 cases ( MoCD and review) 显示文摘 | Bayram E Topcu Y Karakaya P | 2013 | Eur J Paediatr Neurol2013，17，1： | 1 |
| 19 | Effects of different doses of remifentanil infusion on hemodynamics and recovery in children undergoing pediatric diagnostic cardiac catheterization显示文摘 | Kaynar A Kelsaka E Karakaya D | | 0，，： | 1 |
| 20 | Behavioural effects of chronic exposure to subanesthetic concentrations of halothane,sevoflurane and desflurane in rats显示文摘 | Ozer M Baris S Karakaya D | 2006 | Can J Anaesth2006，53，7： | 1 |
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