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| 1 | Emergency cholecystectomy vs percutaneous cholecystostomy plus delayed cholecystectomy for patients with acute cholecystitis显示文摘BACKGROUND: In low-risk patients with acute cholecystitis who did not respond to nonoperative treatment, we prospectively compared treatment with emergency laparoscopic cholecystectomy or percutaneous transhepatic cholecystostomy followed by delayed cholecystectomy.METHODS: In 91 patients(American Society of Anesthesiologists class I or II) who had symptoms of acute cholecystitis ≥72 hours at hospital admission and who did not respond to nonoperative treatment(48 hours), 48 patients were treated with emergency laparoscopic cholecystectomy and 43 patients were treated with delayed cholecystectomy at ≥4 weeks after insertion of a percutaneous transhepatic cholecystostomy catheter. After initial treatment, the patients were followed up for 23 months on average(range 7-29).RESULT: Compared with the patients who had emergency laparoscopic cholecystectomy, the patients who were treated with percutaneous transhepatic cholecystostomy and delayed cholecystectomy had a lower frequency of conversion to open surgery [19(40%) vs 8(19%); P=0.029], a frequency of intraoperative bleeding ≥100 mL [16(33%) vs 4(9%); P=0.006],a mean postoperative hospital stay(5.3±3.3 vs 3.0±2.4 days;P=0.001), and a frequency of complications [17(35%) vs 4(9%);P=0.003].CONCLUSION: In patients with acute cholecystitis who presented to the hospital ≥72 hours after symptom onset and did not respond to nonoperative treatment for 48 hours, percutaneous transhepatic cholecystostomy with delayed laparoscopic cholecystectomy produced better outcomes and fewer complications than emergency laparoscopic cholecystectomy. | Feza Y Karakayali Aydincan Akdur Mahir Kirnap Ali Harman Yahya Ekici G?han Moray | 2014 | Hepatobiliary & Pancreatic Diseases International2014,13,3: | 20 |
| 2 | Surgical and interventional management of complications caused by acute pancreatitis显示文摘Acute pancreatitis is one of the most common gastrointestinal disorders worldwide. It requires acute hospitalization, with a reported annual incidence of 13 to 45 cases per 100000 persons. In severe cases there is persistent organ failure and a mortality rate of 15% to 30%, whereas mortality of mild pancreatitis is only 0% to 1%. Treatment principles of necrotizing pancreatitis and the role of surgery are still controversial. Despite surgery being effective for infected pancreatic necrosis, it carries the risk of long-term endocrine and exocrine deficiency and a morbidity and mortality rate of between 10% to 40%. Considering high morbidity and mortality rates of operative necrosectomy, minimally invasive strategies are being explored by gastrointestinal surgeons, radiologists, and gastroenterologists. Since 1999, several other minimally invasive surgical, endoscopic, and radiologic approaches to drain and debride pancreatic necrosis have been described. In patients who do not improve after technically adequate drainage, necrosectomy should be performed. When minimal invasive management is unsuccessful or necrosis has spread to locations not accessible by endoscopy, open abdominal surgery is recommended. Additionally, surgery is recognized as a major determinant ofoutcomes for acute pancreatitis, and there is general agreement that patients should undergo surgery in the late phase of the disease. It is important to consider multidisciplinary management, considering the clinical situation and the comorbidity of the patient, as well as the surgeons experience. | Feza Y Karakayali | 2014 | World Journal of Gastroenterology2014,20,37: | 16 |
| 3 | Amifostine enhances the antioxidant and hepatoprotective effects of UW and HTK preservation solutions显示文摘AIM:To investigate whether amifostine contributes to the antioxidant and cytoprotective effects of histidinetryptophan-ketoglutarate(HTK)and University of Wisconsin(UW)preservation solutions.METHODS:Forty-eight Sprague Dawley male ratswere equally divided into six groups:(1)ringer Lactate(RL)group;(2)RL+amifostine(RL+A)group;(3)HTK group;(4)HTK+A group;(5)UW group;and(6)UW+A group.Rats in the RL+A,HTK+A and UW+A groups were administered amifostine intraperitoneally at a dose of 200 mg/kg prior to laparotomy.The RL group was perfused with RL into the portal vein.The RL+A group were perfused with RL into the portal vein after amifostine administration.The HTK group received an HTK perfusion while the HTK+A group received an HTK perfusion after administration of amifostine.The UW group received a perfusion of UW,while the UW+A group received a UW perfusion after amifostine administration.Liver biopsy was performed to investigate histopathological,immunochemical[transferase mediated dUTP nick end labeling(TUNEL),inducible nitric oxide syntetase(iNOS)]and ultrastructural alterations.Biochemical alterations were determined by examining levels of alanine aminotransferase,alkaline phosphatase and nitric oxide in the perfusion fluid.RESULTS:Pathological sinusoidal dilatation and centrilobular hydropic alteration were significantly lower in the groups that received amifostine prior to preservation solution perfusion.Although the best results were obtained in the UW+A group,we did not observe a statistically significant difference between the UW+A and HTK+A groups.iNOS grades were significantly lower in the amifostine groups 12 h after treatment.When the amifostine groups were compared against each other,the iNOS grades obtained from the UW+A and HTK+A groups were similar while the RL+A group had a much poorer score.TUNEL assays demonstrated a lower apoptosis ratio in the amifostine groups than in the non-amifostine groups 12 h after treatment.No statistically significant difference was observed between the UW+A and HTK+A groups for apoptosis.Cellular ultrastructure was best preserved in the UW+A and HTK+A groups.CONCLUSION:Here,we show that preoperative administration of a single dose of amifostine is sufficientto minimize the preservation damage in hepatic cells. | Sami Akbulut Sinasi Sevmis Hamdi Karakayali Nilüfer Bayraktar Muge Unlukaplan Ergun Oksuz Atilla Dagdeviren | 2014 | World Journal of Gastroenterology2014,20,34: | 3 |
| 4 | Liver Transplantation in Management of Alveolar Echinococcosis: Two Case Reports显示文摘 | G. Moray R. Shahbazov S. Sevmis H. Karakayali A. Torgay G. Arslan N. Savas U. Yilmaz M. Haberal | 2009 | Transplantation Proceedings2009,,7: | 2 |
| 5 | Network coordination for spectrally efficient communication in cellular systems 显示文摘 | Karakayali M K Foschini G J Valenzuela R A | 2006 | IEEE Wireless Communications Magazine2006,13,4: | 1 |
| 6 | An analysis of decentralized collection and processing of end-of-life products 显示文摘 | Karakayali I Emir-Farinas H Akcali E | 2007 | Journal of Operations Management2007,25,6: | 1 |
| 7 | An analysis of decentralized collection and processing of end-of-life products显示文摘 | Ibrahim Karakayali Hülya Emir-Farinas Elif Akcali | 2007 | Journal of Operations Management2007,,6: | 1 |
| 8 | Successful living-related heterotopic auxiliary liver transplantation for chronic Budd-Chiari syndrome显示文摘 | Haberal M Karakayali H Boyacioglu S | 1999 | Transplant Proc1999,31,7: | 1 |
| 9 | An analysis of decentralized collection and processing of end-d-life products显示文摘 | Karakayali I Hulya Emir-Farinas Akcali E | 2007 | Journal of Operations Management2007,25,6: | 1 |
| 10 | Long term follow of 102 living kidney donors显示文摘 | KARAKAYALI H MORLY A DEMIRAG A | 1998 | Transplant Proc1998,30,: | 1 |
| 11 | An analysis of de- centralized collection and processing of end of life prod- ucts显示文摘 | Karakayali I Arinas H Akcali E | 2007 | Journal of Operations Management2007,25,6: | 1 |
| 12 | Long-term follow-up of 102 living kidney donors显示文摘 | Karakayali H Morly G Ddmirag A | 1998 | Transplant Proc1998,30,6: | 1 |
| 13 | Hypophosphatemia in living liver donors显示文摘 | Filik L Karakayali H Dalgi A | 2006 | Transplant Proc2006,38,2: | 1 |
| 14 | Coordinating multiple antenna cellular networks to achieve enormous spectral efficiency 显示文摘 | Foschini G J Karakayali K Valenzuela R A | 2006 | IEE Proceedings-Communications2006,153,4: | 1 |
| 15 | Liver transplantation for Wilsons disease显示文摘 | Sevmis S Karakayali H Aliosmanoglu I | 2008 | Transplant Proc2008,40,1: | 1 |
| 16 | Effect of graft type on postoperative liver function recovery in living liver donors 显示文摘 | Karakayali H Pehlivan S Yagmurdur MC | 2009 | Transplant Proc2009,41,7: | 1 |
| 17 | Conversion to sirolimus for chronic allograft nephropathy and calcineurin inhibitor toxicity and the adverse effects of sirolimus after conversion显示文摘 | Sayin B Karakayali H Colak T | 2009 | Transplant Proc2009,41,7: | 1 |
| 18 | OKT3 treatment for steroid-resistant acute rejection in kidney transplantation 显示文摘 | Sevmis S Emiroglu R Karakayali F | 2005 | Transplant Proc2005,37,7: | 1 |
| 19 | Network coordination for speetrally efficient communications in cellular systems 显示文摘 | Karakayali M K Foschini G J Valenzuela R A | 2006 | IEEE Wireless Communications2006,13,4: | 1 |
| 20 | Hepatic segmental liver transplantation in children显示文摘 | Haberal M Arda IS Karakayali H | 2000 | Transplant Proc2000,32,3: | 1 |