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67篇 您的检索式:作者名="Karau"
    题名 作者 年代 出处 被引量
1Lack of correlation between Treg quantification assays in inflammatory bowel disease patients显示文摘AIM:To compare the number of regulatory T-cells( Tregs) measured by flow cytometry with those obtained using a real-time quantitative PCR(q PCR) method in patients suffering from inflammatory bowel disease(IBD).METHODS:Tregs percentages obtained by both flow cytometry and q PCR methods in 35 adult IBD patients,18 out of them with Crohn′s disease(CD)and 17 with ulcerative colitis(UC)were compared to each other as well as to scores on two IBD activity questionnaires using the Harvey Bradshaw Index(HBI)for CD patients and the Simple Colitis Clinical Activity Index(SCCAI)for UC patients.The Treg percentages by flow cytometry were defined as CD4+CD25highCD127lowFOXP3+cells in peripheral blood mononuclear cells,whereas the Treg percentages by q PCR method were determined as FOXP3 promoter demethylation in genomic DNA.RESULTS:We found an average of 1.56%±0.78%Tregs by using flow cytometry,compared to 1.07%±0.53%Tregs by using q PCR in adult IBD patients.There were no significant correlations between either the percentages of Tregs measured by flow cytometry or q PCR and the HBI or SCCAI questionnaire scores in CD or UC patients,respectively.In addition,there was no correlation between Treg percentages measured by q PCR and those measured by flow cytometry(r=-0.06,P=0.73;Spearman Rho).These data suggest that,either Treg-related immune function or the clinical scores in these IBD patients did not accurately reflect actual disease activity.Until the cause(s)for these differences are more clearly defined,the resultssuggest caution in interpreting studies of Tregs in various inflammatory disorders.CONCLUSION:The two methods did not produce equivalent measures of the percentage of total Tregs in the IBD patients studied which is consistent with the conclusion that Tregs subtypes are not equally detected by these two assays.Gunnar Brandhorst Darinka Todorova Petrova Sebastian Weigand Christoph Eberle Nicolas von Ahsen Jessica Schmitz Frank Christian Schultze Dirk Raddatz Michael Karaus Michael Oellerich Philip D Walson 2015World Journal of Gastroenterology2015,21,11:2
2Cholecystokinin's role in regulation of colonic motility in health and in irritable bowell sydrome显示文摘Niedexau C Faber S Karaus M 1992Gastroenterology1992,102,:1
3The effects of performance and team cohesion on attribution:a longitudinal simulation显示文摘Michalisin M.D Karau S.J Tangpong C 0,,57:1
4Social loafing: A meta-analytic review and theoretieal integration显示文摘Karau S J Williams K D 1993Journal of personality and social psychology1993,65,4:1
5Top management team cohesion and superior industry returns 显示文摘Michalisin M D Karau S J Tangpong C 2004Group and Organization Management2004,29,1:1
6Reinforcing the glass ceiling via stereotype threst:Gender-stereotypic television commercials persuade women to avoid leadership positions显示文摘 Karau 2002Journal of Applied Psychology2002,,5:1
7Determining landscape extent for succession and disturbance simulation modeling显示文摘Karau E C Keane R E 2007Landscape Ecology2007,22,7:1
8Role congruity theory ofprejudice toward female leaders显示文摘EAGLY A H KARAU S J 2002Psychological Review2002,109,3:1
9Social loafing:A meta-analysis review and theoretical integration显示文摘Karau S J & Williams K D 1993Journal of Personality and Social Psychology1993,65,:1
10Use of cervical cerclage as a treatment option for cervical in- competence: patient characteristics, presentation and management over a 9 year period in a Kenyan centre 显示文摘Karau PB Mutwiri MG Ogeng'o JA 2013Afr J Reprod Health2013,17,1:1
11Dawson Pulmonary arterial morphometry from microfocal X-ray computed tomography Am 显示文摘Kelly L Karau Robert C 2001Physiol Heart Circ Physiol2001,281,6:1
12Gender and the Effectiveness of Leaders:A Meta-analysis显示文摘EAGLY A H KARAU S J MAKHIJANI M G 1995Psychological Bulletin1995,117,12:1
13The enfluence of particle size distribution and operating condition on the adsorption performance in Fluidized Bed显示文摘 Benken C Thommes J 1997Biotech&Bioeng1997,55,1:1
14Structure-function relationships in the pulmonary arterial tree显示文摘Dawson CA Krenz GS Karau KL 1999J Appl Physiol1999,86,:1
15Hydrodynamics and performance in fluidized bed adsorption显示文摘THOMMES J WEIHER M KARAU A 1995Biotechnol Bioeng1995,48,:1
16Working Environment and the Research Productivity of Doctoral Students in Management显示文摘Kim K Karau S J 2010Journal of Education for Business2010,,85:1
17Occurrence of obstructive sleep related respiratory dis-order in conjunction with gastroesophageal reflux显示文摘HEINEMANN S GRAF KI KARAUS M 1995Pneumologie1995,491,:1
18Preparation and stability of interferon-α-containing liposomes 显示文摘Karau C Petszulat M Schmidt P C 1996Int J Pharm1996,128,1:1
19Responsiveness toHIV education and VCT services among Kenyan rural women:A community-based survey显示文摘Karau PB Winnie MS Geoffrey M 2010Afr J Reprod Health2010,14,3:1
20Social loaring: A meta-analytic review and theoretical integration 显示文摘Karau S J & Williams K D 1993Journal of Personality and Social Psychology1993,,65:1
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