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| 1 | Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens显示文摘Objective:To evaluate the antibacterial properties ot Allium sativum(garlic) cloves and Zingiber officinale(ginger) rhizomes against multi-drug resistant clinical pathogens causing nosocomial infection.Methods:The cloves of garlic and rhizomes of ginger were extracted with 95%(v/v) ethanol.The ethanolic extracts were subjected to antibacterial sensitivity test against clinical pathogens.Results:Anti-bacterial potentials of the extracts of two crude garlic cloves and ginger rhizomes were tested against five gram negative and two gram positive multi-drug resistant bacteria isolates.All the bacterial isolates were susceptible to crude extracts of both plants extracts.Except Enterobacter sp.and Klebsiella sp.,all other isolates were susceptible when subjected to ethanolic extracts of garlic and ginger.The highest inhibition zone was observed with garlic(19.4S mm) against Pseudomonas aeruginosa(P.aeruginosa).The minimal inhibitory concentration was as low as 67.00 μg/mL against P.aeruginosa.Conclusions:Natural spices of garlic and ginger possess effective anti-bacterial activity against multi-drug clinical pathogens and can be used for prevention of drug resistant microbial diseases and further evaluation is necessary. | Ponmurugan Karuppiah Shyamkumar Rajaram | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，8： | 14 |
| 2 | Bifurcation and spatiotemporal patterns of a density-dependent predator-prey model with Crowley-Martin functional response显示文摘 | M. Sivakumar K. Balachandran K. Karuppiah | 2017 | International Journal of Biomathematics2017，10，6： | 3 |
| 3 | Effect of angiotensin converting enzyme gene I/D polymorphism in South Indian children with nephrotic syndrome显示文摘Nephrotic syndrome is one of the most common childhood kidney diseases. It is mostly found in the age group of 2 to 8 years. Around 10%-15% of nephrotic syndrome cases are non-responders of steroid treatment(SRNS).Angiotensin converting enzyme(ACE)(I/D) gene association studies are important for detecting kidney disease and herein we assessed the association of ACE(I/D) polymorphism with nephrotic syndrome in South Indian children. We recruited 260 nephrotic syndrome(162 boys and 98 girls) and 218(140 boys and 78 girls) control subjects. ACE I/D polymorphism was analyzed by PCR using genotype allele specific primers. In ACE(I/D), we did not find significant association for the ungrouped data of nephrotic syndrome children and the control subjects. Kidney biopsies were done in 86 nephrotic syndrome cases(minimal change disease, n = 51;focal segmental glomerulosclerosis, n = 27;diffuse mesangial proliferation, n = 8). We segregated them into the minimal change disease/focal segmental glomerulosclerosis groups and observed that the ACE’D’ allele was identified with borderline significance in cases of focal segmental glomerulosclerosis and the ’Ⅰ’ allele was assessed as having very weak association in cases of minimal change disease. ’Ⅱ’ genotype was weakly associated with minimal change disease. Gender specific analysis revealed weak association of’ID’ genotype with female nephrotic syndrome in females. Dominant expression of DD genotype was observed in males with nephrotic syndrome. Our finding indicated that ACE(I/D) has moderate association with focal segmental glomerulosclerosis. However, due to the limited number of biopsy proven focal segmental glomerulosclerosis subjects enrolled, further studies are required to confirm these results. | Aravind Selvin Kumar Ramanathan Balakrishnan Karuppiah Murali Vijayan Kamaraj Raju Dhivakar Mani Rathika Chinniah Manikandan Thirunavukkarasu Padma Malini Ravi Jeyaram Illiayaraja Krishnan Prabha Senguttuvan | 2019 | The Journal of Biomedical Research2019，33，3： | 2 |
| 4 | Optimal Feature Extraction Using Greedy Approach for Random Image Components and Subspace Approach in Face Recognition显示文摘An innovative and uniform framework based on a combination of Gabor wavelets with principal component analysis (PCA) and multiple discriminant analysis (MDA) is presented in this paper. In this framework, features are extracted from the optimal random image components using greedy approach. These feature vectors are then projected to subspaces for dimensionality reduction which is used for solving linear problems. The design of Gabor filters, PCA and MDA are crucial processes used for facial feature extraction. The FERET, ORL and YALE face databases are used to generate the results. Experiments show that optimal random image component selection (ORICS) plus MDA outperforms ORICS and subspace projection approach such as ORICS plus PCA. Our method achieves 96.25%, 99.44% and 100% recognition accuracy on the FERET, ORL and YALE databases for 30% training respectively. This is a considerably improved performance compared with other standard methodologies described in the literature. | Mathu Soothana S.Kumar Retna Swami Muneeswaran Karuppiah | 2013 | Journal of Computer Science & Technology2013，28，2： | 2 |
| 5 | L-asparaginase production by mangrove derived Bacillus cereus MAB5:optimization by response surface methodology显示文摘Objective:To isolate marine bacteria,statistically optimize them for maximum asparaginase production.Methods:In the present study,statistically based experimental designs were applied to maximize the production of L-asparaginase from bacterial strain of Bacillus cereus(B.cereus) MAB5(HQ675025) isolated and identified by 16S rDNA sequencing from mangroves rhizosphere sediment.Results:Plackett-Barman design was used to identify the interactive effect of the eight variables viz.yeast extract,soyabean meal,glucose,magnesium sulphate,KH2PO4,wood chips,aspargine and sodium chloride.All the variables are denoted as numerical factors and investigated at two widely spaced intervals designated as -1(low level) and +1(high level). The effect of individual parameters on L-asparaginase production was calculated.Soyabean meal,aspargine,wood chips and sodium chloride were found to be the significant among eight variables.The maximum amount of L-asparaginase produced(51.54 IU/mL) from the optimized medium containing soyabean meal(6.282 8 g/L),aspargine(5.5 g/L),wood chips(1.383 8 g/L) and NaCl(4.535 4 g/L).Conclusions:The study revealed that,it is useful to produce the maximum amount of L-asparaginase from B.cereus MAB5 for the treatment of various infections and diseases. | Thenmozhi C Sankar R Karuppiah V Sampathkumar P | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，6： | 2 |
| 6 | Cycloartane Type Triterpenoids from the Rhizomes of Polygonum Bistorta显示文摘 | Karuppiah Pillai Manoharan Tan Kwong Huat Benny Daiwen Yang | 2005 | Phytochemistry2005，66，19： | 1 |
| 7 | Anodic degradation of CI reactive blue 221 using graphite and IrO2/TaO2/RuO2 coated titanium electrodes显示文摘 | Karuppiah M Thalamadai Raju G Bhaskar | | 0，，： | 1 |
| 8 | Atmospheric wet deposition of PAHs to the sea-surface microlayer 显示文摘 | LER LIM OLIVER WURL SUBRAMANIAN KARUPPIAH | 2007 | Marine Pollution Bulletin2007，54，： | 1 |
| 9 | Elevated BNP with normal systolic function in asymptomatic individuals at-risk for heart failure: a marker of diastolic dysfunction and clinical risk 显示文摘 | Karuppiah S Graham F Ledwidge M | 2006 | Ir J Med Sci2006，175，4： | 1 |
| 10 | Heavy metals in sediments of two Chesapeake Bay tributaries-Wicomico and Pocomoke Rivers显示文摘 | GUPTA G KARUPPIAH M | 1996 | Journal of Hazardous Materials1996，50，： | 1 |
| 11 | Contamination by Persistent Organic Pollutants in Dumping Sites of Asian Developing Countries: Implication of Emerging Pollution Sources显示文摘 | N. H. Minh T. B. Minh N. Kajiwara T. Kunisue A. Subramanian H. Iwata T. S. Tana R. Baburajendran S. Karuppiah P. H. Viet B. C. Tuyen S. Tanabe | 2006 | Archives of Environmental Contamination and Toxicology2006，，4： | 1 |
| 12 | Persistent organic pollutants in mangrove food webs in Singapore显示文摘 | BAYEN S WURL O KARUPPIAH S | 2005 | Chemosphere2005，61，： | 1 |
| 13 | Heavy metals in sediments of twoChesapeake Bay tributaries-Wicomico and PocomokeRivers显示文摘 | Gupta G Karuppiah M | 1996 | Journal of Hazardous Materials1996，50，： | 1 |
| 14 | Role of the PRMT1- DDAH-ADMA axis in the regulation of endothelial nitric oxideproduc- tion显示文摘 | POPE A J KARUPPIAH K CARDOUNEL A J | 2009 | Pharmacol Research2009，60，6： | 1 |
| 15 | Persistent organic pollutants in mangrove food webs in Singapore 显示文摘 | BAYEN S WURL O KARUPPIAH S | 2005 | Chemosphere2005，61，3： | 1 |
| 16 | Cyclodextrins as protein folding aids 显示文摘 | Karuppiah N Sharma A | 1995 | Biochem Biophys Res Commun1995，211，： | 1 |
| 17 | Multinuclear magneticresonance spectrosopic and semiempirical molecular orbital(ami) studies of substituted anisoles显示文摘 | Karuppiah P Senthamaraikannan K | 1994 | The Chemical So-ciety of Japan1994，67，： | 1 |
| 18 | Neurosurgieal endoscopic training via a realistic 3-dimensional model with pathology 显示文摘 | Waran V Narayanan V Karuppiah R | 2015 | Simul Heahhc2015，10，1： | 1 |
| 19 | A simple heuristic for reducing the number o{ scenarios in two-stage stochastic programming 显示文摘 | KARUPPIAH R MARTIN M GROSSMANN I E | 2010 | Computers Chemical Engineering2010，34，8： | 1 |
| 20 | A Novel and sensitive Amperometric Hydrazine Sensor Based on Gold Nanoparticles Decorated Graphite Nanosheets Modi- fied Screen Printed Carbon Electrode显示文摘 | Karuppiah C Palanisamy S Chen S M | 2014 | Electrochimica Acta2014，139，： | 1 |
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