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6篇 您的检索式:作者名="Katchen"
    题名 作者 年代 出处 被引量
1NPR1 as a transgenic crop protection strategy in horticultural species显示文摘The NPR1(NONEXPRESSOR OF PATHOGENESIS RELATED GENES1)gene has a central role in the long-lasting,broad-spectrum defense response known as systemic acquired resistance(SAR).When overexpressed in a transgenic context in Arabidopsis thaliana,this gene enhances resistance to a number of biotic and abiotic stresses.Its position as a key regulator of defense across diverse plant species makes NPR1 a strong candidate gene for genetic engineering disease and stress tolerance into other crops.High-value horticultural crops face many new challenges from pests and pathogens,and their emergence exceeds the pace of traditional breeding,making the application of NPR1-based strategies potentially useful in fruit and vegetable crops.However,plants overexpressing NPR1 occasionally present detrimental morphological traits that make its application less attractive.The practical utility of NPR-based approaches will be a balance of resistance gains versus other losses.In this review,we summarize the progress on the understanding of NPR1-centered applications in horticultural and other crop plants.We also discuss the effect of the ectopic expression of the A.thaliana NPR1 gene and its orthologs in crop plants and outline the future challenges of using NPR1 in agricultural applications.Katchen Julliany P.Silva Nasser Mahna Zhonglin Mou Kevin M.Folta 2018Horticulture Research2018,5,1:3
2A dual role fortumor-derived chemokine RANTES (CCL5) 显示文摘Adler E P Lemken C A Katchen N S Kurt R A 2003Immunol Lett2003,90,23:1
3A dual role for tumorderived chemokine RANTES (CCL5)显示文摘Adler EP l emken CA Katchen NS 2003Immunol Lett2003,90,23:1
4A dual role for tumor-derived chemokine RANTES (CCL5)显示文摘Evan P. Adler Charles A. Lemken Nicholas S. Katchen Robert A. Kurt 2003Immunology Letters2003,,2:1
5A dual role for tumor-derived chemokine RANTES (CCL5)显示文摘Adler EP Lemken CA Katchen NS 2003Immunology Lett2003,90,23:1
6Differential gene regulatory pathways and co-expression networks associated with fire blight infection in apple(Malus×domestica)显示文摘Apple cultivars with durable resistance are needed for sustainable management of fire blight,the most destructive bacterial disease of apples.Although studies have identified genetic resistance to fire blight in both wild species and cultivated apples,more research is needed to understand the molecular mechanisms underlying host–pathogen interaction and differential genotypic responses to fire blight infection.We have analyzed phenotypic and transcriptional responses of‘Empire’and‘Gala’apple cultivars to fire blight by infecting them with a highly aggressive E.amylovora strain.Disease progress,based on the percentage of visual shoot necrosis,started showing significant(p<0.001)differences between‘Empire’and‘Gala’4 days after infection(dai).‘Empire’seems to slow down bacterial progress more rapidly after this point.We further compared transcriptome profiles of‘Empire’and‘Gala’at three different time points after fire blight infection.More genes showed differential expression in‘Gala’at earlier stages,but the number of differentially expressed genes increased in‘Empire’at 3 dai.Functional classes related to defense,cell cycle,response to stress,and biotic stress were identified and a few co-expression gene networks showed particular enrichment for plant defense and abiotic stress response genes.Several of these genes also co-localized in previously identified quantitative trait locus regions for fire blight resistance on linkage groups 7 and 12,and can serve as functional candidates for future research.These results highlight different molecular mechanisms for pathogen perception and control in two apple cultivars and will contribute toward better understanding of E.amylovora-Malus pathosystem.Katchen Julliany Pereira Silva Jugpreet Singh Ryland Bednarek Zhangjun Fei Awais Khan 2019Horticulture Research2019,6,1:0
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