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您的检索式：作者名="Kathy H. Li"
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| 1 | Proteomics Analysis Reveals Post-Translational Mechanisms for Cold-Induced Metabolic Changes in Arabidopsis显示文摘基因表示和新陈代谢的导致寒冷的变化是批评的让植物幸存结冰。主要由改变基因表示,到不会结冻的低温度的一个时期的暴露增加植物忍耐到作为冷环境适应知道的 freezinga 现象。在在结冰下面的温度落下指以前,寒冷也导致快速的新陈代谢的变化,它提供立刻的保护。为对寒冷的如此的快速的新陈代谢的回答的分子的机制仍然保持大部分未知。这里,我们使用 Arabidopsis thaliana proteome 的亚 cellular 部分的分析结合了的二维的差别胶化电气泳动(2-D DIGE ) 由双人脚踏车团 spectrometry 看到鉴定在 Arabidopsis 识别早寒冷应答的蛋白质。这些蛋白质包括涉及淀粉降级,三 HSP100 蛋白质,在 tricarboxylic 酸周期的几蛋白质,和蔗糖新陈代谢的四酶。在冷处理之上, Disproportionating 酶 2 (DPE2 ) ,使麦芽糖产生代射变化到葡萄糖的 cytosolic transglucosidase,在 centrifugation 小团部分很快增加了并且在可溶的部分减少了。与 DPE2 酶的活动的导致寒冷的 inactivation 一致,没有影响 C 重复有约束力的抄写因素(CBF ) , dpe2 异种显示出增加的结冰忍耐 transcriptional 小径。这些结果支持一个模型那导致寒冷的 inactivation DPE2 导致麦芽糖的快速的累积,它是保护房间免受结冰的伤害的导致寒冷的兼容溶质损坏。这研究为在对突然的温度的植物保护的新陈代谢的酶掉的糖类的快速的 translational 以后规定的一个关键角色提供证据。 | Tian Li Shou-Ling XU Juan A. Oses-Prieto Sunita Putil Peng Xu Rui-Ju Wang Kathy H. Li David A. Maltby Liz-He An Alma L. Burlingame Zhi-Ping Deng Zhi-Yong Wang | 2011 | Molecular Plant2011，4，2： | 6 |
| 2 | The Arabidopsis B-box protein BZS1/BBX20 interacts with HY5 and mediates strigolactone regulation of photomorphogenesis显示文摘Plant growth is controlled by integration of hormonal and light-signaling pathways. BZS1 is a B-box zinc finger protein previously characterized as a negative regulator in the brassinosteroid(BR)-signaling pathway and a positive regulator in the light-signaling pathway. However, the mechanisms by which BZS1/BBX20 integrates light and hormonal pathways are not fully understood. Here, using a quantitative proteomic workflow, we identified several BZS1-associated proteins, including light-signaling components COP1 and HY5. Direct interactions of BZS1 with COP1 and HY5 were verified by yeast two-hybrid and co-immunoprecipitation assays. Overexpression of BZS1 causes a dwarf phenotype that is suppressed by the hy5 mutation, while overexpression of BZS1 fused with the SRDX transcription repressor domain(BZS1-SRDX) causes a long-hypocotyl phenotype similar to hy5, indicating that BZS1's function requires HY5. BZS1 positively regulates HY5 expression, whereas HY5 negatively regulates BZS1 protein level, forming a feedback loop that potentially contributes to signaling dynamics. In contrast to BR,strigolactone(SL) increases BZS1 level, whereas the SL responses of hypocotyl elongation, chlorophyll and HY5 accumulation are diminished in the BZS1-SRDX seedlings, indicating that BZS1 is involved in these SL responses. These results demonstrate that BZS1 interacts with HY5 and plays a central role in integrating light and multiple hormone signals for photomorphogenesis in Arabidopsis. | Chuang-Qi Wei Chih-Wei Chien Lian-Feng Ai Jun Zhao Zhenzhen Zhang Kathy H. Li Alma L. Burlingame Yu Sun Zhi-Yong Wang | 2016 | Journal of Genetics and Genomics2016，43，9： | 5 |
| 3 | Alcohol intake and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium (PanScan)显示文摘 | Dominique S. Michaud Alina Vrieling Li Jiao Julie B. Mendelsohn Emily Steplowski Shannon M. Lynch Jean Wactawski-Wende Alan A. Arslan H. Bas Bueno-de-Mesquita Charles S. Fuchs Myron Gross Kathy Helzlsouer Eric J. Jacobs Andrea LaCroix Gloria Petersen Wei | 2010 | Cancer Causes & Control2010，，8： | 1 |
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