|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy显示文摘IgG 的 Fc 区域的 Glycosylation 在安全和治疗学的抗体的临床的功效上有深刻影响。当复杂类型的 oligosaccharide 纳入了 Fc 的 Asn297 的 biantennary 为抗体受动器功能是必要的时,海藻糖和外部手臂的糖属于核心 heptasaccharide 产生结构的异质(glycoforms ) 展出唯一的生物活动。因此,有效、量的 glycan 分析技术为治疗学的抗体的发展和质量控制是日益重要的,并且 Fc 的 glycan 侧面作为批评优秀属性被认出。在过去的十年,我们 IgG-Fc 的结构 / 功能上的 glycosylation 的影响的理解通过 X 光检查结晶、原子的磁性的回声研究很快成长了,它为新奇抗体治疗学的设计提供可能性。而且,用基于 endoglycosidase 的 glycosynthases 的 chemoenzymatic glycoengineering 途径可以作为下一代的治疗学的抗体与理想的功能便于同类的 IgG glycoforms 的发展。因此, Fc glycans 是在精确药的时代的治疗学的 IgG 抗体的安全,功能,和功效的改进的肥沃的地面。 | Yusuke Mimura Toshihiko Katoh Radka Saldova Roisin O'Flaherty Tomonori Izumi Yuka Mimura-Kimura Toshiaki Utsunomiya Yoichi Mizukami Kenji Yamamoto Tsuneo Matsumoto Pauline M. Rudd | 2018 | Protein & Cell2018，9，1： | 2 |
| 2 | Accuracy, of in vivo coronary plaque morphology assessment : a validation study of in vivo virtual histology compared with in vitro histopathology显示文摘 | Nasu K Tsuchikane E Katoh O | 2006 | J Am Coll Cardiol2006，47，12： | 1 |
| 3 | Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation显示文摘 | Katoh O Tauchi H Kawaishi K | 1995 | Cancer Res1995，55，23： | 1 |
| 4 | Predictors of angiographic restenosis after drug eluting stents in the coronary arteries: contemporary practice in real world patients显示文摘 | Rathore S Terashima M Katoh O | 2009 | EuroIntervention2009，5，3： | 1 |
| 5 | Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor 显示文摘 | Katoh O Takahashi T Oguri T | 1998 | Cancer Res1998，，23： | 1 |
| 6 | Accuracy of in vivo coronary plaque morphology asscssment:a validation study of in vivo virtual histology compared with in vitro histopathology 显示文摘 | Nasu K Tsuchikane E Katoh O | 2006 | J Am Coil Cardiol2006，47，12： | 1 |
| 7 | Approach for chronic total occlusion with intravascular ultrasound guided reverse controlled antegrade and retrograde tracking technique; single center experience显示文摘 | Dai J Katoh O Kyo E | 2013 | J Interv Cardiol2013，26，5： | 1 |
| 8 | Effect of fluvastatin on progression of coronary atherosclerotic plaque evaluated by virtual histology intravascular ultrasound 显示文摘 | Nasu K Tsuchikane E Katoh O | 2009 | JACC Cardiovasc Interv2009，2，7： | 1 |
| 9 | Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor显示文摘 | Katoh O Takahashi T Oguri T Kuramoto K Mihara K Kobayashi M | 1998 | Cancer Res1998，58，23： | 1 |
| 10 | Effects of phenyl derivatives of dihydropyrazineswith ability to generate radical species on Escherichia coli显示文摘 | Takeda O Takechi S Katoh T | 2005 | Biol Pharm Bull2005，28，7： | 1 |
| 11 | CD44 is critical for airway accumulation of antigen-specific Th2,but not Th1,cells induced by antigen challenge in mice显示文摘 | Katoh S Kaminuma O Hiroi T | | 0，，11： | 1 |
| 12 | Accuracy of in vivo coronary plaque morphology assessment: a validation study of in vivo virtual histology compared with in vitro histopathology 显示文摘 | Nasu K Tsuchikane E Katoh O | 2006 | J Am Coil Cardiol2006，47，12： | 1 |
| 13 | Expression of the VEGF receptor gene KDR in hematopoietic cells and inhibitory effect of VEGF on apop totic cell death caused by ionizing radiation显示文摘 | Tauchi W Kawaishi K | 1995 | Cancer Res1995，55，： | 1 |
| 14 | Coronary Septal Collaterals as an Access for the Retrograde Approach in the Percutaneous Treatment of Coronary Chronic Total Occlusions 显示文摘 | Surmely JF Katoh O Tsuchikame E | 2007 | Catheterization and Cardiovascular Interventions J2007，69，： | 1 |
| 15 | Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor显示文摘 | Katoh O Takahashi T Oguri T | 1998 | Cancer Res1998，58，23： | 1 |
| 16 | Coronary septal collaterals as an access for the retrograde approach in the percutaneous treatment of coronary chronic total occlusions显示文摘 | SURMELY J F KATOH O TSUCHIKANE E | 2007 | Catheter Cardiovasc Interv2007，69，： | 1 |
| 17 | Expression of the vascu- lar endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic ceils and inhibitory effect of vegf on apoptotic cell death caused by ionizing radiation显示文摘 | Katoh O Tauchi H Kawaishi K | 1995 | Cancer Res1995，55，23： | 1 |
| 18 | Effect of fluvastatin on progression of coronary atherosclerotic plaque evaluated by virtual histology intravascular ultrasound显示文摘 | Nasu K Tsuchikane E Katoh O | 2009 | JACC Cardiovasc Interv2009，2，7： | 1 |
| 19 | Retrograde percutaneous recanalization of chronic total occlusion of the coronary arteries:Procedural outcomes and predictors of success in contemporary practice显示文摘 | RATHORE S KATOH O MATSUO H | 2009 | Circ Cardiovasc Interv2009，2，： | 1 |
| 20 | The efficacy of a bilateral approach for treating lesions with chronic total occlusions the CART(controlled antegrade and retrograde subintimal tracking)registry显示文摘 | KIMURA M KATOH O TSUCHIKANE E | 2009 | JACC Cardiovasc Interv2009，2，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员