| 6 | Cytoprotective and anti-inflammatory effects of kernel extract from Adenanthera pavonina on lipopolysaccharide-stimulated rat peritoneal macrophages显示文摘Objective:To investigate mechanism of anti-inflammatory activity of Adenanthera pavonina(A.pavonina) extracts.Methods:Rat peritoneal macrophages were treated with different concentrations of lipopolysaccharide and H_2O_2 in the presence and absence of kernel extract from A.pavonina.Nitric oxide,superoxide anion generation,cell viability and nuclear fragmentation were investigated.Results:The pre-treatment of kernel extract from A.pavonina suppressed nitric oxide,superoxide anion,cell death,nuclear fragmentation in lipopolysaccharide and H_2O_2stimulated or induced macrophages,respectively.Conclusions:These results suggest that A.pavonina extract suppresses the intra cellular peroxide production. | Arunagirinathan Koodalingam Ramar Manikandan Munisamy Indhumathi Ethala Subramani Kaviya | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，2： | 0 |
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