5篇
您的检索式：作者名="Kaye Marion"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Characteristics of hepatocellular carcinoma in cirrhotic and non-cirrhotic non-alcoholic fatty liver disease显示文摘AIM: To determine characteristics and prognosticpredictors of patients with hepatocellular carcinoma(HCC) in association with non-alcoholic fatty liver disease(NAFLD).METHODS: We reviewed the records of all patients with NAFLD associated HCC between 2000 and 2012. Data collected included demographics; histology; presence or absence of cirrhosis, size and number of HCC, alpha-fetoprotein, body mass index(BMI), and the presence of diabetes, hypertension, or dyslipidaemia.RESULTS: Fifty-four patients with NAFLD associated HCC were identified. Mean age was 64 years with 87% male. Fifteen percent(8/54) were not cirrhotic. 11%, 24% and 50% had a BMI of < 25 kg/m2, 25-29 kg/m2 and ≥ 30 kg/m2 respectively. Fifty-nine percent were diabetic, 44% hypertensive and 26% hyperlipidaemic. Thirty-four percent of the patients had ≤ 1 of these risk factors. Non-cirrhotics had a significantly larger mean tumour diameter at diagnosis than cirrhotics(P = 0.041). Multivariate analysis did not identify any other patient characteristics that predicted the size or number of HCC.CONCLUSION: HCC can develop in NAFLD without cirrhosis. At diagnosis such tumours are larger than those in cirrhotics, conferring a poorer prognosis. | Christopher Leung Sern Wei Yeoh Desmond Patrick Shara Ket Kaye Marion Paul Gow Peter W Angus | 2015 | World Journal of Gastroenterology2015，21，4： | 24 |
| 2 | Overcoming the overlap problem in the assignment of ^1H NMR spectra of larger proteins by use of three-dimensional heteronuclear ^1H-^15S N Hartmann-Hahn-muhiple quantum coherence and nuclear Overhauser-muhiple quantum coherence spectroscopy: Application to interleukin 1β显示文摘 | Marion D Driscoll P C Kay L E etal | 1989 | Biochemistry1989，28，15： | 1 |
| 3 | A prenylation inhibitor prevents production of infectioushepatitis delta virus particles显示文摘 | Bordier BB Marion PL Ohashi K Kay MA Greenberg HB CaseyJL | 2002 | J Virol2002，76，10： | 1 |
| 4 | Sustained survival of human hepatocytes in mice: A model for in vivo infection with human hepatitis B and hepa- titis delta viruses 显示文摘 | Ohashi K Marion PL Nakai H Meuse L Cullen JM Bordier BB Schwall R Greenberg HB Glenn JS Kay MA | 2000 | Nat Med2000，6，3： | 1 |
| 5 | Inhibition of hepatitis B virus in mice by RNA interference显示文摘 | McCaffrey AP Nakai H Pandey K Huang Z Salaza FH Xu H Wieland SF Marion PL Kay MA | 2003 | Nat Biotechnol2003，21，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员