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| 1 | Late-onset acute rejection after living donor liver transplantation显示文摘AIM: To investigate the incidence and risk factors of late-onset acute rejection (LAR) and to clarify the effectiveness of our immunosuppressive regime consisting of life-long administration of tacrolimus and steroids. METHODS: Adult living donor liver transplantation recipients (n = 204) who survived more than 6 mo after living donor liver transplantation were enrolled. Immunosuppression was achieved using tacrolimus and methylprednisolone. When adverse effects of tacrolimus were detected, the patient was switched to cyclosporine. Six months after transplantation, tacrolimus or cyclosporine was carefully maintained at a therapeutic level. The methylprednisolone dosage was maintained at 0.05 mg/kg per day by oral administration. Acute rejections that occurred more than 6 mo after the operation were defined as late-onset. The median follow- up period was 34 mo. RESULTS: LAR was observed in 15 cases (7%) and no chronic rejection was observed. The incidence of hyperlipidemia, chronic renal failure, new-onset post- transplantation diabetes, and deep fungal infection were 13%, 2%, 24%, and 17%, respectively. Conversion from tacrolimus to cyclosporine was required in 38 patients (19%). Multivariate analysis revealed that a cyclosporine- based regimen was significantly associated with LAR. CONCLUSION: Both LAR and drug-induced adverseevents happen at a low incidence, supporting the safety and efficacy of the present immunosuppression regimen for living donor liver transplantation. | Nobuhisa Akamatsu Yasuhiko Sugawara Sumihito Tamura Junichi Keneko Yuichi Matsui Kiyoshi Hasegawa Masatoshi Makuuchi | 2006 | World Journal of Gastroenterology2006，12，41： | 4 |
| 2 | Evaluation of stapler hepatectomy during a laparoscopic liver resection显示文摘 | Joseph F. Buell Brice Gayet Ho‐Seong Han Go Wakabayashi Ki‐Hun Kim Giulio Belli Robert Cannon Bob Saggi Hiro Keneko Alan Koffron Guy Brock Ibrahim Dagher | 2013 | HPB2013，，11： | 3 |
| 3 | Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue显示文摘 | Keneko Y Maruyama T Takegami K | 2005 | Eur Radiol2005，15，7： | 1 |
| 4 | Where do gibberellin biosynthesis and gibberellin signaling occur in rice plants显示文摘 | Keneko M ltoh H Inukai Y | | 0，，： | 1 |
| 5 | High toxicity of hydroxy-aluminum polymer ions to plant roots显示文摘 | WAGATSUMA T KENEKO M | 1987 | Soil Science and Plant Nutrition1987，33，： | 1 |
| 6 | A TNF receptor family member TROY, is a corcceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors 显示文摘 | Park JB Yiu G Keneko S | 2005 | Neuron2005，45，3： | 1 |
| 7 | Indentifieation of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays显示文摘 | Shirota Y Keneko S Honda M | 2001 | Heptology2001，33，： | 1 |
| 8 | High toxicity of hydroxy-aluminum polymer ions to plant roots显示文摘 | Wa G A Tsuma T Keneko M | 1987 | Soil Science Plant Nutrition1987，33，1： | 1 |
| 9 | High toxicity of hydroxy-aluminum polymer ions to plant roots显示文摘 | Wagatsuma T Keneko M | 1987 | Soil Science and Plant Nutrition1987，33，： | 1 |
| 10 | Long-term results of operation for non-small cell lung cancer in the elderly显示文摘 | Ishida T Yokoyama H Keneko S | 1990 | Ann Thorac Surg1990，50，6： | 1 |
| 11 | A new rabbit model for the study on cervical compressive myelopathy显示文摘 | Kanchiku T TaguchiT Keneko K | 2001 | Orthop Res2001，23，4： | 1 |
| 12 | A new rabbit model for the study on cervical compressive myelopathy显示文摘 | KANCHILU T TAGUCHI T KENEKO K | 2001 | Or- thop Res2001，23，4： | 1 |
| 13 | A new rabbit model for the study on cervical compressive myelopathy 显示文摘 | Kanchiku T Taguchi T Keneko K | 2001 | J Orthop Res2001，19，4： | 1 |
| 14 | High toxicity of hydroxy-aluminum polymer ions to plant roots 显示文摘 | Wa G A Tsuma T Keneko M | 1987 | Soil Science Plant Nutrition1987，33，1： | 1 |
| 15 | New approach to graphite synthesis:electrochemical carbonization of hexachlorobuta-1,3-diene 显示文摘 | Nishihara H Harada H Keneko S | 1991 | J Chem Soc Faraday Trans1991，87，8： | 1 |
| 16 | A new rabbit model for the study on cervical compressive myelopathy 显示文摘 | Kanchiku T Taguchi T Keneko K | 2001 | Orthop Res2001，4，： | 1 |
| 17 | High toxicity of hydroxy-aluminum polymer ions to plant roots显示文摘 | WAGATSUMA T KENEKO M | 1987 | Soil Sci Plant Nutr1987，33，1： | 1 |
| 18 | A new rabbit model for the study on cervical compressive myelopathy 显示文摘 | Kanchiku T Taguchi T Keneko K | 2001 | J Orthop Res2001，19，4： | 1 |
| 19 | New Approacn to Graphite Synthesis:Electrochemical Carbonization of Hexachlorobuta-1,3-Diene 显示文摘 | Nishihara H Harada H Keneko S | 1991 | J Chem Soc Faraday Trans1991，87，8： | 1 |
| 20 | Long-term evaluation of ultra-early operation for hypertension intracerebral hemorrhage in 100cases显示文摘 | KENEKO M TANADA K SHIMADA T | 1983 | Neurosurgery1983，58，6： | 1 |
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